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PHASE I PS-341 IN ADVANCED MALIGNANCIES AND VARYING DEGREES OF LIVER DYSFUNCTION

PHASE I PS-341 IN ADVANCED MALIGNANCIES AND VARYING DEGREES OF LIVER DYSFUNCTION
PS-341 在晚期恶性肿瘤和不同程度肝功能障碍中的 I 期
批准号：
7607528
负责人：
GEORGE WILDING
金额：
$0.04万
依托单位：
UNIVERSITY OF WISCONSIN-MADISON
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
项目状态：
已结题
起止时间：
2006-12-01 至 2007-09-16
来源：
https://reporter.nih.gov/project-details/7607528
关键词：
Computer Retrieval of Information on Scientific Projects DatabaseDrug KineticsFundingGrantInstitutionLiver DysfunctionMalignant NeoplasmsMaximum Tolerated DosePS341 cpdPatientsPharmacodynamicsPhasePurposeResearchResearch PersonnelResourcesSafetySourceUnited States National Institutes of Health

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research is to identify the pharmacokinetic and pharmacodynamic profile of PS341 in patients with advanced malignancy and varying degrees of liver dysfunction. The research will also evaluate the safety, tolerability, and the maximum tolerated dose of PS341 for patients with varying degrees of liver dysfunction.
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CRCHD
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海外基金