SUBPROJECT: HLA TYPING AND DNA REPOSITORY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 本研究的目的是对最近完成的美国国立卫生研究院支持的硬皮病患者进行人类白细胞抗原(人类白细胞抗原)配型。由于硬皮病是一种不常见的疾病，人们对此知之甚少，其目的是存储这些硬皮病患者的DNA，以便将来对这种疾病潜在的遗传异常进行遗传学研究。标本将被送往田纳西大学健康科学中心保存在标本储存库中。主要站点是德克萨斯大学。MUSC和其他几个地点正在分包。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to perform HLA(human leukocyte antigen)typing on patients with scleroderma who were enrolled in the recently completed NIH sponsored "Multicenter Phase II Trial of Oral Bovine Type I Collagen in Scleroderma". Since scleroderma is as uncommon disease about which little is known, the purpose is to store DNA from these scleroderma patients for future genetic studies of potential genetic abnormalities in the disease. Specimens will be sent to the University of Tennessee Health Science Center to be kept in a specimen repository. Primary site is UT. MUSC plus several other sites are under subcontract.