COBRE: WVU: SIGNAL TRANSDUCTION & CANCER: FLOW CYTOMETRY CORE FACILITY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 西弗吉尼亚大学(WVU)流式细胞术核心设施成立于2002年，是信号转导和癌症生物医学研究卓越中心(Cobre)赠款的一部分。流式细胞仪核心设备为西弗吉尼亚大学和邻近机构提供流式细胞仪分析和细胞分类，并支持Cobre研究人员以及其他由NIH资助的项目。在过去3年中，该设施支持了23份同行评议的出版物和20多份摘要的研究。本申请书描述了1)研究所的历史、当前的仪器和人员，2)核心设施的运作计划，3)核心设施在实现科布雷资助的研究目标和西弗吉尼亚大学其他项目方面的贡献，4)研究所在当前和未来癌症相关项目中的作用，包括科布雷拨款续期申请中所述的研究项目，以及5)关于为最先进的细胞FACSAria细胞分类器获得资金的成功努力的报告。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The West Virginia University (WVU) Flow Cytometry Core Facility was established in 2002 as part of the Center for Biomedical Research Excellence (COBRE) grant in Signal Transduction and Cancer. The Flow Cytometry Core Facility offers analytic flow cytometry and cell sorting to WVU and neighboring institutions, and supports COBRE investigators as well as other NIH-funded projects. In the past 3 years the facility has supported research leading to 23 peer-reviewed publications and over 20 abstracts. This application describes 1) the Facilitys history, current instrumentation, and personnel, 2) the Core Facility Operational Plan, 3) the contribution of the Core Facility in fulfilling research objectives of COBRE-funded and other projects at WVU, 4) the Facilitys role in current and future cancer-related projects including research projects described in the COBRE grant renewal application, and 5) a report on successful efforts at obtaining funding for a state of the art cell FACSAria cell sorter.