COBRE: WVU: SIGNAL TRANSDUCTION & CANCER: FLOW CYTOMETRY CORE FACILITY

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 研究中心，而研究中心不一定是研究者所在的机构。 西弗吉尼亚大学（WVU）流式细胞术核心设施成立于2002年，是信号转导和癌症生物医学研究卓越中心（COBRE）资助的一部分。 流式细胞仪核心设施为西弗吉尼亚大学和邻近机构提供分析流式细胞仪和细胞分选，并支持COBRE研究人员以及其他NIH资助的项目。 在过去的3年里，该设施支持的研究导致了23篇同行评审的出版物和20多篇摘要。 本申请描述了1）设施的历史，目前的仪器，和人员，2）核心设施的运作计划，3）核心设施在实现COBREF资助的研究目标和其他项目在西弗吉尼亚大学的贡献，4）该设施的作用，在当前和未来的癌症相关的项目，包括研究项目中描述的COBRE资助更新申请，和5）在获得资金的最先进的细胞FACSAria细胞分选的国家成功的努力的报告。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The West Virginia University (WVU) Flow Cytometry Core Facility was established in 2002 as part of the Center for Biomedical Research Excellence (COBRE) grant in Signal Transduction and Cancer. The Flow Cytometry Core Facility offers analytic flow cytometry and cell sorting to WVU and neighboring institutions, and supports COBRE investigators as well as other NIH-funded projects. In the past 3 years the facility has supported research leading to 23 peer-reviewed publications and over 20 abstracts. This application describes 1) the Facilitys history, current instrumentation, and personnel, 2) the Core Facility Operational Plan, 3) the contribution of the Core Facility in fulfilling research objectives of COBRE-funded and other projects at WVU, 4) the Facilitys role in current and future cancer-related projects including research projects described in the COBRE grant renewal application, and 5) a report on successful efforts at obtaining funding for a state of the art cell FACSAria cell sorter.