MEASUREMENT OF T1-T2 RELAXIVITIES OF LIPOSOMAL GD-DTPA

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 本工作的目的是测定包裹不同浓度的造影剂的Gd-DTPA脂质体的T1和T2弛豫度。这些研究将确定在使用T1加权技术进行磁共振成像时可以在体内使用的最佳配方。这将导致获得具有更高信噪比(SNR)和对比度噪声比(CNR)的图像。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goals of this work are to determine T1 and T2 relaxivities of Liposomal Gd-DTPA encapsulating different concentration of gadolinium contrast agents. The studies will identify the optimal formulation that can be used in vivo when performing MR imaging using T1-weighted techniques. This will result in obtaining images with higher signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR).