Diabetes Endocrinology Research Center

糖尿病内分泌研究中心

• 批准号: 7336646
• 负责人: LAWRENCE CHAN
• 金额: $ 113.62万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-03-20 至 2013-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7336646
• 关键词: Diabetes; Endocrinology; Research; Center

DESCRIPTION, OVERALL (provided by applicant): We seek to establish a Diabetes Endocrinology Research Center (DERC) at Baylor College of Medicine. The DERC will promote diabetes research among a diverse biomedical research base that spans clinical metabolism and nutrition, type 1 and type 2 diabetes and their macrovascular and microvascular complications, lipid homeostasis, adipose biology and energy metabolism, basic molecular and cellular biology, molecular endocrinology, islet biology and gene therapy. Baylor College of Medicine has an extremely strong ongoing biomedical research base in diabetes/endocrinology that can be categorized into four major areas: [1] clinical diabetes research, [2] basic and translational research, [3] molecular endocrinology, and [4] adipogenesis, with membership representing 10 departments and multiple disciplines. The DERC will foster interactions and facilitate collaboration among diabetes/endocrinology researchers, and entice nondiabetes researchers to commit to diabetes research. It will interact with and strengthen existing Research Centers and NIH Training Programs at Baylor and set up new enrichment programs. With College support, the PI (Dr. Chan) set up a highly successful pilot DERC Pilot & Feasibility (P/F) Program in 2004 and, in the last two years, has used internal College funds to support 4 P/F projects selected from 78 applications (2 each from 44 applications in 2004 and 34 applications in 2006) from 10 departments. The DERC will support diabetes research through the following Research Core Laboratories: Clinical Translational Investigation, Microarray, Biostatistics and Bioinformatics, Proteomics, Gene Vector, Mouse Phenotyping, and Nonhuman Primate (in collaboration with the Southwest Foundation for Biomedical Research in San Antonio), that will support diabetes research of DERC faculty and of P/F projects. The DERC will further broaden the diabetes research base at Baylor College of Medicine, while generating strong synergism with other programs and institutions in the Texas Medical Center and in the greater Southwest United States.

描述，总体（由申请人提供）： 我们试图在贝勒医学院建立一个糖尿病内分泌研究中心（DERC）。 DERC将在跨越临床代谢和营养的多样化生物医学研究基础中促进糖尿病研究，1型和2型糖尿病及其大血管和微血管并发症，脂质生物学和能量代谢，基本分子和细胞生物学，分子enelectolology，ISET，ISET，基因，脂肪生物学和能量代谢，脂肪生物学和能量代谢。贝勒医学院在糖尿病/内分泌学方面具有非常强大的生物医学研究基础，可以归类为四个主要领域：[1]临床糖尿病研究，[2]基础和转化研究，[3]分子内分泌学和[4]脂肪形成，具有代表10个部门和多个学科的成员资格。 DERC将促进互动并促进糖尿病/内分泌研究人员之间的合作，并诱使非糖研究人员致力于进行糖尿病研究。它将与贝勒（Baylor）的现有研究中心和NIH培训计划进行互动，并建立新的丰富计划。在大学的支持下，PI（Chan博士）于2004年建立了非常成功的飞行员DERC飞行员和可行性（P/F）计划，在过去的两年中，在过去的两年中，使用了内部大学资金来支持从78个申请中选出的4个P/F项目（2004年的44个应用程序和2006年的44个应用程序中的2个项目）。 DERC将通过以下研究核心实验室支持糖尿病研究：临床翻译研究，微阵列，生物统计学和生物信息学，蛋白质组学，基因载体，小鼠 表型和非人类灵长类动物（与圣安东尼奥的西南生物医学研究基金会合作），将支持DERC教师和P/F项目的糖尿病研究。这 DERC将进一步扩大贝勒医学院的糖尿病研究基础，同时与德克萨斯州医疗中心和大西南部的其他计划和机构产生强大的协同作用。