Diabetes Endocrinology Research Center

耶鲁大学糖尿病内分泌研究中心成立于1993年春天，旨在促进大学糖尿病及相关代谢和内分泌疾病的研究。该中心汇集了来自内科，儿科，免疫生物学，生物学，细胞生物学，分子生物物理学和生物化学，生物工程，遗传学，分子，细胞和发育生物学，生理学，药理学，外科，骨科，神经外科，神经病学，精神病学，妇产科，诊断放射学，心理学，病理学，实验室医学，以及来自公共卫生和护理学院和皮尔斯实验室。成员的研究活动范围非常广泛，从基础分子生物学到全身生理学和糖尿病患者的治疗。然而，成员们， 在与糖尿病、内分泌学和代谢相关的研究中有共同的兴趣，或者 这对于理解其发病机制或开发新的治疗策略至关重要。的 耶鲁DERC的设计旨在开发一个基础设施，可以作为一种催化剂，刺激 创新研究。该中心的基石是其六个研究核心，提供资助的基本和 临床研究者有机会更有效地利用资源，扩大他们的研究范围。 研究项目。临床代谢和新的糖尿病翻译核心促进代谢 研究的病人，而分子，转基因，动物遗传学，动物生理学和细胞 生物学核心，包括动物资源计划提供研究人员的工具，创造和测试 新型动物模型，从分子开始，以生物学结果结束。行政 核心监督中心的运作，其试点/可行性项目和丰富计划，并帮助 以协调糖尿病患者为基础的研究DERC的目标是：1）刺激 多学科互动，特别是基础和临床科学家之间的互动; 2）有效地组织时间 消耗和/或昂贵的技术，通过核心设施，以提高调查人员的生产力 开展糖尿病相关领域的研究; 3）通过试点可行性促进新的研究计划 项目; 4）提高研究培训的质量; 5）创造一个激励性的制度环境， 加强研究工作，制定新的战略，以预防和治疗糖尿病和相关的代谢和 在地方和国家一级开展内分泌失调问题的研究。

The Yale Diabetes Endocrinology Research Center was established in the Spring of 1993 with the goal of promoting research in diabetes and related metabolic and endocrine disorders at the University. The Center brings together a multidisciplinary group of nearly 100 member scientists as well as professional supporting staff, new investigators and research trainees from the Departments of Internal Medicine, Pediatrics, Immunobiology, Biology, Cell Biology, Molecular Biophysics and Biochemistry, Bioengineering, Genetics, Molecular, Cellular and Developmental Biology, Physiology, Pharmacology, Surgery, Orthopedics, Neurosurgery, Neurology, Psychiatry, Obstetrics and Gynecology, Diagnostic Radiology, Psychology, Pathology, Laboratory Medicine, and from the Schools of Public Health and Nursing and the Pierce Laboratory. The scope of the research activities of the membership is very broad, ranging from basic molecular biology to whole body physiology and the treatment of diabetic patients. The members, however, share a common interest in research that is related to diabetes, endocrinology and metabolism or is fundamental to understanding its pathogenesis or for the development of new treatment strategies. The design of the Yale DERC is aimed at developing an infrastructure that could serve as a catalyst to stimulate innovative research. The cornerstone of the Center is its six Research Cores that provide funded basic and clinical investigators with the opportunity to more efficiently utilize resources and expand the scope of their research programs. The Clinical Metabolism and the new Diabetes Translational Cores facilitate metabolic research in patients, whereas the Molecular, Transgenic, Animal Genetics, Animal Physiology and Cell Biology Cores that comprise the Animal Resource Program offer investigators the tools to create and test novel animal models starting from the molecule and ending with biological outcomes. The Administrative Core oversees the operation of the Center, its Pilot/Feasibility Project and Enrichment Programs, and helps to coordinate patient-based research in diabetes. The goals of the DERC are to: 1) stimulate multidisciplinary interactions, particularly between basic and clinical scientists; 2) efficiently organize time consuming and/or costly techniques through Core facilities to enhance the productivity of investigators conducting research in diabetes related areas; 3) promote new research programs through pilot feasibility projects; 4) enhance the quality of research training, and 5) create a stimulating institutional environment that enhances research efforts to develop new strategies to prevent and treat diabetes and related metabolic and endocrine disorders at the local and national level.