INBRE UNDERGRADUATE RESEARCH EXPERIENCE CORE

INBRE 本科研究经验核心

• 批准号: 7610186
• 负责人: JEFFREY O MILLER
• 金额: $ 20.58万
• 依托单位: UNIVERSITY OF DELAWARE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7610186
• 关键词: Adipocytes; Affect; African American; Aluminum Oxide; Area; Behavior; Biology; Biomedical Research; Biotechnology; Birds; Bismuth; Blood capillaries; Bone Development; Bone Marrow; Bronchoscopy; Cancer Center; Capsid Proteins; Carbon; Career Choice; Caring; Cell surface; Chemistry; Cholesterol; Clinical; Communities; Complement component C1s; Computer Retrieval of Information on Scientific Projects Database; Computers; Couples; Crystallization; DNA; Data; Delaware; Depth; Detection; Discipline of Nursing; Domestic Fowls; Dose; Embryo; Endothelial Cells; Engineering; Enterococcus faecalis; Evaluation; Event; Excision; Faculty; Funding; GYPA gene; Gene Expression Profile; Genomics; Glycine max; Glycophorin A; Grant; Growth; Health Sciences; Healthcare Systems; Helix (Snails); Hispanics; Home environment; Hour; Housing; Institutes; Institution; Internships; Kinetics; Knowledge; Lavandula; Length of Stay; Life; Lipoproteins; Lung; Malignant neoplasm of esophagus; Medicago truncatula; Medical; Mentors; Messenger RNA; Methyl-CpG-Binding Protein 2; Microbial Biofilms; Microsporidia; Mining; Minority; National Institute of General Medical Sciences; Neurons; Niobium; Numbers; Nursing Faculty; Nursing Schools; Oligonucleotides; Oligopeptides; Participant; Phase; Physical activity; Placement; Plant Roots; Population; Postoperative Period; Process; Production; Program Evaluation; Progress Reports; Proteins; Pseudomonas aeruginosa; Pulmonary Function Test/Forced Expiratory Volume 1; Pulmonary Surfactant-Associated Protein B; Regulation; Reporting; Research; Research Ethics; Research Personnel; Research Project Grants; Resources; Role; Saccharomyces cerevisiae; School Nursing; Scientist; Series; Site; Small Nucleolar RNA; Snow; Sodium Chloride; Source; Soybeans; Stress; Students; Surveys; System; Testing; Translational Research; Transportation; Trypsin Inhibitors; Tumor Necrosis Factor-alpha; United States National Institutes of Health; Universities; Veronica; Virus; Week; Woman; Work; cancer cell; capillary; career; college; ear helix; experience; gene repair; grandparent; inhibitor/antagonist; interest; laser tweezer; lung cancer screening; malignant breast neoplasm; member; molybdate; mutant; nanofiber; posters; programs; response; reticulocalbin; simulation; skills; symposium; university student; virtual reality

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Delaware INBRE Annual Progress Report (APR) 2007 Grant No. 5P20RR016472-2007 Undergraduate Research Experience Core Core Directors: Ms. Jeanette Miller, DBI Assistant Director Dr. Veronica Rempusheski, UD School of Nursing Core Objective: To strengthen the biomedical research skills of undergraduates by involving them in faculty research. Summer Undergraduate Research Internships Overview: The Delaware INBRE grant supported twenty-seven undergraduate research interns in a ten-week program conducted June - August 2006. The program required students to work forty hours per week at their research assignments, and to prepare a poster or talk for an end of summer research symposium, hosted by the University of Delaware through a grant from the Howard Hughes Medical Institute. All INBRE students participated in a four-session seminar series on clinical and translational research and research ethics, hosted by INBRE partner Christiana Care Health System. Each student was also provided a stipend, housing allowance, and when needed, transportation to required events. A number of students continue their research projects during the academic year, and present at poster sessions at national meetings. Institutions Involved: All six Delaware INBRE partner institutions participated in the program, as host research sites or as a source of students. This year featured an increased number of cross-institutional assignments, with 40% of students conducting research at an institution other than their home institutions. During the placement process, students were asked to describe their areas of scientific interest, to review faculty research descriptions and to suggest up to four labs of interest throughout the INBRE network. Whenever possible, students were placed in one of their labs of choice. Some thirty network faculty were involved, either as research mentors or in selecting student participants from their respective institutions. For the second year, the group included nursing faculty and students from the University of Delaware and Wesley College. Jeanette Miller, Assistant Director, Delaware Biotechnology Institute provided student placement and program oversight. Student Data: The diverse student group included 60% women and 30% underrepresented students (five African-American and two Hispanic students). Interns were sophomores, juniors and seniors in life and health science majors, including biology, biotechnology, chemistry, electrical and computer engineering, and nursing. Research interns also included four students involved in the two-year histotechnician program at Delaware Technical & Community College. To be candidates for an internship, students were required to have a minimum GPA of 3.00. Program Evaluation: Interns completed evaluations at the conclusion of the internship. Students reported that the internship was a very positive experience, which in many instances confirmed or catalyzed a students interest in a biomedical research career. Students often reported that the internship developed or gave them confidence in some of their own skills: that they could function as a member of a lab team; that they could develop a deep understanding of a scientific project and talk about it to other scientists, which they had the opportunity to do at the end-of-summer research symposium. All INBRE students prepared scientific posters, and two INBRE students were invited to give symposium talks during the August 2006 capstone event. A long-term survey of Delaware BRIN/INBRE students is planned for spring 2007, to gather data on students continued educational and career choices, and the effect of the internship experience on this choice. INBRE students also present their research at other venues, including at the NIH NISBRE meeting, which took place in July 2006. Students are encouraged to apply to national meetings that host undergraduate researchers, such as the NIGMS Annual Biomedical Research Conference for Minority Students (ABRCMS). INBRE has assisted three students in attending this conference. Delaware INBRE Summer 2006 Undergraduate Research Intern Projects Ansbach, Catrina Faculty Mentor - Brougher Surfactant Protein B Expression in Domestic Fowl Embryos Barninger, Debra Faculty Mentor - Harrington Degraduation of Genomic DNA from Helix apersa Bates, Tessa Faculty Mentors - Prettyman, Wheeler Grandparents Knowledge of Grandchildrens Physical Activity Callahan, Stephanie Faculty Mentor - Kmiec Impact of Msh2 Deficiency on Rad51 Foci Formation in Response to Oligonucleotides Criel, Michelle Faculty Mentors - Cannon, Polek Young Couples Confronting Breast Cancer: Stress Related to Being a Mom Edwards, Jonathan Faculty Mentor - Furst Gelation Kinetics of ¿-Hairpin Oligopeptides Using Laser Tweezer Microrheology Engel, Liora Faculty Mentor - Bais Root Secretion Mining for P. aeruginosa and E. faecalis Biofilm Inhibitors Feld, Samantha Faculty Mentor - Cancer Center @ Christiana Care Correlation of Preoperative FEV1 Values and Postoperative Hospital Stay Following Lung Resection Forstrom, Robert Faculty Mentor - Steiner A Virtual-Reality Approach for the Treatment of Jegede, Yewande Faculty Mentor - DiMaria Identification of a Small Nucleolar RNA in Microsporidia Johnson, Laura Sherrier Identification of Nodulation Mutants in an EMS-mutagenized Population of Medicago truncatula Kell, Copeland Faculty Mentor - Stoleru Alumina Nanofibers Generated Through a Anodization Koyoshi, Fumie Faculty Mentor - Polenova An Evaluation of Solvolytic Mechanisms at a Trigonal Carbon Lavender, Marysol Faculty Mentor - Usher Cholesterol Depletion in Adipocytes and its Affects on Lipoproteins E and C1 Mancini, John Faculty Mentor - Robinson Testing the Effect of DTT on the Unfolded Protein Response Mechanism in Saccharomyces cerevisiae Manrai, Arjun Faculty Mentor - Kmiec Analysis of the Targeted Gene Repair Transcriptome in Mammalian Systems Mills, Timothy Faculty Mentor - Wommack Bacterial Production in the Chesapeake and Delaware Bays Mlynarski, Stacey Faculty Mentor - Fondong, Vincent The Gemini virus Coat Protein: Detection of mRNA and Subcellular Localization Niedermeyer, Monica Faculty Mentor - Bauer Lung Cancer Screening Using Low-Dose CT  The Christiana Care Experience Omondi, Arnold Faculty Mentor - DSouza Use of LFERS to Evaluate the Solvolytic Mechanism of Isopropenyl Chloroformate Oren, Rachel Faculty Mentor - Cooper, Farach-Carson Tumor Necrosis Factor Alpha (TNF-¿) Regulation of Reticulocalbin (RCN-1) cell surface expression and Capillary-like formation in Bone Marrow Endothelial Cells (BMECs) Palladino, Gina Faculty Mentor - Lenhoff Crystallization and Aggregation of Soybean Trypsin Inhibitor at Low Salt Concentration: A Phase Behavior Study of Protein Salting In Pomroy, Donna Faculty Mentors - Schanen, Farach-Carson The Role of MeCP2 in Neuron Development and Bone Homesostasis Scott, Evan Faculty Mentors - Bauer Evaluation of Virtual Reality Bronchoscopy Simulation Shankman, Laura Faculty Mentor - Naik Niobium-Doped Bismuth Molybdates Snow, Samantha Faculty Mentor - Brougher Ontogeny of Surfactant Protein B (SP-B) Expression in Avian Lung Vasta, Casey Faculty Mentor - Kmiec ssDNA Oligonucleotides Arrest Growth of Esophageal Cancer Cells

该副本是使用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这是调查员的机构。 特拉华州近交年度进度报告（4月）2007年 赠款号5P20RR016472-2007 本科研究经验核心 核心主管： DBI助理董事Jeanette Miller女士 UD护理学院Veronica Rempusheski博士 核心目的：通过使他们参与教师研究来增强本科生的生物医学研究技能。 夏季本科研究实习 概述： 特拉华州的近亲赠款在2006年6月至8月进行的为期十周的计划中支持了27个本科研究实习生。该计划要求学生每周在研究任务中工作40个小时，并为夏季研究研讨会的结束准备海报或谈话，该研讨会由德拉华大学通过霍华德·休斯医疗机构（Howard Hughes Hughes Medical Institute）主持的夏季研究研讨会。所有INBRE学生都参加了由INBRE合作伙伴Christiana Care Health System主持的有关临床和翻译研究和研究伦理的四节开创性系列。还为每个学生提供了压力，住房津贴以及在需要时运输到所需的活动。许多学生在学年中继续他们的研究项目，并在国家会议上参加海报会议。 涉及的机构： 所有六个特拉华州的近亲合作伙伴机构都以主机研究网站或学生的来源参加了该计划。今年的跨机构任务增加了，有40％的学生在其内部机构以外的机构进行研究。在安置过程中，要求学生描述他们的科学兴趣领域，审查教师研究描述，并在整个INBRE网络中建议多达四个感兴趣的实验室。只要有可能，学生就会被安置在他们选择的一个实验室中。作为研究导师，或从各自机构中选择学生参与者时，有30个网络教师参与其中。第二年，该小组包括特拉华大学和卫斯理学院的护士教师和学生。特拉华州生物技术学院助理主任珍妮特·米勒（Jeanette Miller）提供了学生的安排和计划监督。 学生数据： 潜水员的学生团体包括60％的女性和30％的代表性学生（五名非裔美国人和两个西班牙裔学生）。实习生是生命和健康科学专业的大二学生，大三和老年人，包括生物学，生物技术，化学，电气和计算机工程以及护士。研究实习生还包括四名参与特拉华州技术与社区学院的历史技术学计划的学生。要成为实习生的候选人，学生的最低GPA为3.00。 计划评估： 实习生在实习结束时完成了评估。学生报告说，实习是一种非常积极的经历，在许多情况下，这在生物医学研究生涯中证实或催化了学生的有趣。学生经常报告说，实习生发展或使他们对自己的某些技能有信心：他们可以作为实验室团队的成员发挥作用；他们可以对科学项目有深刻的了解，并与其他科学家讨论，他们有机会在夏末研究研讨会上进行。所有近亲学生都准备了科学海报，并邀请两名INBRE学生在2006年8月的Capstone活动期间进行研讨会。 计划在2007年春季对特拉华州Brin/Inbre学生进行长期调查，以收集有关学生继续教育和职业选择的数据，以及实习经验对此选择的影响。 INBRE学生还在其他场所介绍他们的研究，包括在2006年7月举行的NIH NISBRE会议上。鼓励学生申请举办本科研究人员的全国会议，例如NIGMS年度生物医学研究会议（ABRCMS）。 INBRE协助三名学生参加了这次会议。 2006年特拉华州近亲企业本科研究实习生项目 Ansbach，Catrina 教师导师-Brougher 表面活性剂蛋白B在家禽胚胎中的表达 Barninger，Debra 教师导师 - 哈灵顿 螺旋APERSA的基因组DNA降解 贝茨，泰莎 教师导师 - Prettyman，Wheeler 祖父母了解孙子的体育锻炼 卡拉汉，斯蒂芬妮 教师导师-KMIEC MSH2缺乏对寡核苷酸的响应RAD51焦点形成的影响 克里尔，米歇尔 教师导师 - 坎农，POLEK 面对乳腺癌的年轻夫妇：与妈妈有关的压力 爱德华兹，乔纳森 教师导师 - 弗斯特 使用激光Tweezer Microheology的凝胶动力学 - hairpin寡肽 恩格尔，利奥拉 教师导师-Bais 铜绿假单胞菌和粪肠球菌生物膜抑制剂的根分泌挖掘 费尔德，萨曼莎 教师导师 - 癌症中心 @ Christiana Care 术前FEV1值和肺部切除后后期住院的相关性 罗伯特·福斯特罗姆（Forstrom） 教师导师 - 斯坦纳 一种虚拟现实的方法 耶格德，耶鲁德 教师导师-Dimaria 鉴定微孢子虫中的小核仁RNA 约翰逊，劳拉 Sherrier Medicago truncatula的EMS-核烯化群体中的结节突变体的鉴定 凯尔，谷轮 教师导师-Stoleru 氧化铝纳米纤维通过阳极氧化产生 koyoshi，富米 教师导师-Polenova 对三角碳的溶解度机制的评估 薰衣草，马里索尔 教师导师 - 迎来 脂肪细胞中的胆固醇消耗及其对脂蛋白E和C1的影响 曼奇尼，约翰 教师导师 - 鲁滨逊 测试DTT对酿酒酵母中展开的蛋白质反应机制的影响 Manrai，Arjun 教师导师-KMIEC 哺乳动物系统中靶向基因修复转录组的分析 米尔斯，蒂莫西 教师导师-Wommack 切萨皮克和特拉华海湾的细菌生产 Mlynarski，Stacey 教师导师 - Fondong，文森特 双子病毒外套蛋白：mRNA和亚细胞定位的检测 Niedermeyer，莫妮卡 教师导师 - 鲍尔 使用低剂量CT进行肺癌筛查The Christiana护理经验 奥蒙迪，阿诺德 教师导师-D Souza 使用LFER来评估异丙烯基氯仿的溶解度机理 奥伦，瑞秋 教师导师 - 库珀，法拉赫 - 卡森 肿瘤坏死因子α（TNF-）调节网状（RCN-1）细胞表面表达和毛细血管样形成骨髓内皮细胞（BMEC） 帕拉迪诺（Palladino），吉娜（Gina） 教师导师-Lenhoff 低盐浓度下大豆胰蛋白酶抑制剂的结晶和聚集：蛋白质盐的相行为研究 Pomroy，Donna 教师导师-Schanen，Farach -Carson MECP2在神经元发育和骨homesostasis中的作用 斯科特，埃文 教师导师 - 鲍尔 虚拟现实支气管镜检查模拟的评估 劳拉·桑克曼（Shankman） 教师导师-Naik 掺杂尼伯菌的二甲虫 雪，萨曼莎 教师导师-Brougher 表面活性剂蛋白B（SP-B）表达的个体发育 瓦斯，凯西 教师导师-KMIEC ssDNA寡核苷酸的停滞生长食管癌细胞的生长