CORE D CELL CULTURE AND VIRAL VECTOR CORE

核心 D 细胞培养物和病毒载体核心

• 批准号: 7720100
• 负责人: JEONG YOON
• 金额: $ 15.02万
• 依托单位: MAINEHEALTH
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-03-01 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7720100
• 关键词: Biology; Blood Vessels; Cells; Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; Cultured Cells; Fee-for-Service Plans; Funding; Gene Transfer; Grant; Human; Institution; Laboratories; Mouse Strains; Mus; Preparation; Reagent; Research; Research Personnel; Resources; Signaling Molecule; Smooth Muscle Myocytes; Source; United States National Institutes of Health; Viral; Viral Vector; cell immortalization; cost; interest; novel; recombinant virus; research study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This Core was established in 2004 to meet the increasing demand for high quality cells and recombinant viruses in support of COBRE in Vascular Biology projects. The Core is responsible for: (i) the procurement, preparation, and storage of human and murine endothelial and vascular smooth muscle cells; (ii) immortalization of cells derived from novel strains of mice, and (iii) preparation of high titer adenoviral, retroviral, and lentiviral stocks encoding the signaling molecules of interest for gene transfer experiments. The use of high quality cells and viral reagents from a common source will result in more efficient, cost-effective, and more reproducible experiments between collaborating laboratories. Fees-for-service have been implemented so that the Core may become self-sufficient when COBRE funds are no longer available.

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