Research Training in Pediatric Cardiology

描述(由申请人提供)： 该奖项的前十年用于在基础心血管科学研究领域培训S博士和儿科心脏病学研究员，特别是与儿科心脏病学相关的研究领域。从出版记录和受训者获奖后的成就来看，他们的培训经验是优秀的。在这项申请中，我们将扩展我们的项目的成功之处，以提供培训和指导基础科学家以外的临床科学家的途径。NHLBI-32奖项的具体指导方针强烈主张通过基础科学家和临床研究人员之间的协作互动丰富培训环境。最近的儿科心脏病临床网络RFA和儿科心脏发育临床导向研究专门中心也为儿科心脏病学的临床研究提供了大力支持。幸运的是，我们有许多重要的资源来支持MUSC儿科心脏病研究员的临床和基础科学研究培训。我们的培训地点是南卡罗来纳州儿科心脏病学三级临床护理的唯一提供者，也是全州儿科心脏病专家网络的中心，为从重症监护相关假说到流行病学的临床研究提供必要的患者护理活动。重要的机构资源极大地支持了南加州大学儿科心脏病学的临床和基础科学研究的整合。这些特别包括MUSC作为儿童心脏病临床网络资助中心的参与，一个非常成功的临床研究计划理学硕士的存在，一个充满活力的NIH/NHLBI 少数民族机构研究培训计划奖、心血管发育生物学中心和心血管研究方面的生物医学研究卓越中心奖。所有这些项目的主任都是该奖项的副主任或咨询委员会成员。机构资源的整合、受指导的研究兴趣和资源的广度、在研究活动中对指导的承诺以及非常成功的申请者招募环境为南加州大学儿科心脏病学的多学科研究培训创造了优越的环境。该项目中描述的基础科学、临床和转化性博士后研究培训机会加强了目前在MUSC儿科心脏病学之间活跃的协同互动，并展示了MUSC学术环境中丰富的研究活动范围。(摘要结束)

DESCRIPTION (provided by applicant): The first ten years of this award have been directed to training Ph.D.'s and pediatric cardiology fellows in fields of basic cardiovascular science research especially relevant to pediatric cardiology. Their training experiences have been superior as measured by publication records and the post-award achievements of trainees. In this application we will expand on the success of our program to provide pathways for training and mentoring clinical scientists in addition to basic scientists. NHLBI-specific guidelines for T-32 awards strongly advocate training environments enriched by collaborative interactions between basic scientists and clinical investigators. Emphatic support for clinical research in pediatric cardiology has also been provided by recent RFA's for a Pediatric Heart Disease Clinical Network and Specialized Centers of Clinically Oriented Research in Pediatric Heart Development. We are fortunate to have many critical resources to support clinical and basic science research training for pediatric cardiology fellows at MUSC. Our training site is the sole provider of pediatric cardiology tertiary clinical care for the state of South Carolina, and the center of a state-wide network of pediatric cardiologists, resulting in the necessary patient care activities for clinical research ranging from intensive care related hypotheses to epidemiology. Key institutional resources greatly support integration of clinical and basic science research in pediatric cardiology at MUSC. These especially include participation of MUSC as a funded center in the Pediatric Heart Disease Clinical Network, the presence of a highly successful Master of Science in Clinical Research Program, a vigorous NIH/NHLBI Minority Institutional Research Training Program Award, the Cardiovascular Developmental Biology Center, and the Center of Biomedical Research Excellence in Cardiovascular Research Award. The directors of all of these programs are Associate Directors or Advisory Committee members of this award. The integration of institutional resources, the breadth of mentored research interests and resources, the commitment to mentorship in research activities, and a highly successful applicant recruitment environment creates a superior environment for multidisciplinary research training in pediatric cardiology at MUSC. The basic science, clinical, and translational postdoctoral research training opportunities described in this program augment synergistic interactions currently active between pediatric cardiology at MUSC and demonstrate the rich scope of research activities in the MUSC academic environment. (End of Abstract)