Research Training in Childhood Stress, Trauma, and Resilience

项目总结/摘要 越来越多的证据表明，儿童期的压力和创伤对儿童的身心健康有着深远而持久的影响。 行为和身体健康的结果。然而，在阐明 风险机制和新的预防和干预努力，以促进复原力是有限的， 接受过培训的研究人员人数，可进行转化型、了解发展的研究，重点是 童年压力、创伤和恢复力。拟议的儿童压力博士后研究培训， 创伤和复原力（星星T32）采取广泛的方法来应对压力，逆境和创伤， 儿童和家庭及其对整个发展过程中的生物行为机制和健康结果的影响。 该星星T32是一个密集的研究奖学金，旨在准备博士和MD博士后研究员， 对儿童压力，创伤和 这将是布朗医学院唯一由NICHD资助的培训项目。T32将 招收12名博士后研究员（每年2-3名），为期两年，为期五年。研究员将有一个 行为健康相关领域（心理学，公共卫生/流行病学，神经科学）的博士学位或 相关专业（精神病学、儿科学、急诊医学）。该计划包括一个学徒 一个模型，研究员与一个广泛的特殊教师导师进行密切合作， 创新的，NIH资助的，在STAR相关领域的转化研究，往往涉及多样化，服务不足， 弱势群体。导师包括具有广泛研究兴趣的博士和医学博士， 从心理学和精神病学到公共卫生、儿科和急诊的跨学科专业知识 药研究员还将获得涵盖四个关键星星领域的重点教学培训： （B）途径和机制，（c）健康行为和结果，以及（d）干预和 社区伙伴关系，以促进复原力。他们还将获得严格的基础研究培训 设计和统计，赠款写作，负责任的研究行为，专业发展，和切割- 边缘方法论。该计划利用独特的和长期的培训基础设施 米里亚姆医院和布朗精神病学与人类系内部的合作和文化 行为，允许大量的实习同事，教师专家，教学和支持。超过 90%拥有星星导师的往届研究员都从事了成功的研究密集型职业，其中 在博士后研究期间获得了许多出版物。T32还将增强和利用 布朗的记录招聘的高度熟练的实习生候选人，与计划到位，重点 征聘种族/族裔和社会经济多样化的研究员。星星T32符合以下使命： NICHD儿科创伤和危重病分支，包括专注于协作和翻译 研究，以促进发现，预防，治疗和减少各种形式的儿童创伤。

PROJECT SUMMAY / ABSTRACT There is increasing evidence for a profound and persistent impact of childhood stress and trauma on adverse behavioral and physical health outcomes across the lifespan. However, progress toward elucidating mechanisms of risk and novel prevention and intervention efforts to promote resilience is limited by the small number of investigators trained to conduct translational, developmentally-informed research focused on childhood stress, trauma, and resilience. The proposed postdoctoral research training in childhood Stress, Trauma, and Resilience (STAR T32) takes a broad approach to stress, adversity and traumas experienced by children and families and their impact on biobehavioral mechanisms and health outcomes across development. The STAR T32 is an intensive research fellowship designed to prepare PhD and MD postdoctoral fellows to conduct cutting-edge, translational, developmentally-informed research on childhood stress, trauma and resilience, and would be the only NICHD-funded training program within Brown Medical School. The T32 will enroll 12 postdoctoral fellows (2-3 per year) for two-year terms over the five-year award. Fellows will have a PhD in a behavioral health-related field (psychology, public health/epidemiology, neuroscience) or an MD in a related specialty (psychiatry, pediatrics, emergency medicine). The program embraces an apprenticeship model where fellows work closely with one of a broad base of exceptional faculty mentors conducting innovative, NIH-funded, translational research in STAR-related areas often involving diverse, underserved and disadvantaged populations. Mentors include PhDs and MDs with a breadth of research interests and transdisciplinary expertise from psychology and psychiatry to public health, pediatrics and emergency medicine. Fellows will also obtain focused didactic training covering four critical STAR domains: (a) exposures and trauma, (b) pathways and mechanisms, (c) health behaviors and outcomes, and (d) interventions and community partnerships to promote resilience. They will also obtain rigorous foundational training in research design and statistics, grant-writing, responsible conduct of research, professional development, and cutting- edge methodological approaches. The program leverages a unique and long-standing training infrastructure and culture of collaboration within The Miriam Hospital and the Brown Department of Psychiatry and Human Behavior, allowing for a large base of trainee colleagues, faculty experts, didactics and support. More than 90% of past fellows with STAR mentors have gone on to successful, research-intensive careers, with numerous publications obtained during postdoctoral fellowship. The T32 will also enhance and leverage Brown’s track record of recruitment of highly accomplished trainee candidates, with plans in place for focused recruitment of racially/ethnically and socio-economically diverse fellows. The STAR T32 fits with the mission of the NICHD Pediatric Trauma and Critical Illness Branch, including a focus on collaborative and translational research to promote discoveries, and preventing, treating, and reducing all forms of childhood trauma.