IMAGING METHODS FOR IMAGE GUIDED THERAPY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 该项目的总体目标是利用射频激励和射频灵敏度曲线的灵活性来开发混合成像序列，并使这些方法成为增强核磁共振引导治疗应用的资源，特别是基于核磁共振的热疗监测。 我们实现这一目标的具体目标是： (1)开发用于图像引导治疗的混合成像序列，将非傅立叶编码和RF编码与标准傅立叶编码的MRI方法相结合。 (2)开发用于图像引导治疗的具有运动健壮性、单次激发自旋回波行扫描和多对比度平板扫描序列， (3)根据影像引导治疗的需要，开发多种并行成像工具。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The general goal of this project is to exploit the flexibility of RF excitation and RF sensitivity profiles for the development of hybrid imaging sequences and to make these methods available as a resource for enhancing MRI-guided therapy applications, in particular, MRI-based monitoring of thermal therapies. Our specific aims to achieve this goal are to: (1) Develop hybrid imaging sequences for image-guided therapy combining non-Fourier and RF encoding with standard Fourier-encoded MRI methods. (2) Develop motion-robust, single-shot spin-echo line-scan and slab-scan sequences with multiple contrasts for image-guided therapy, (3) Develop a variety of parallel imaging implementations tailored to the needs of image-guided therapy.