Comprehensive Anesthesia Research Training

描述（由申请人提供）：该培训补助金的目标是确保我们的学员学习最先进的研究技术，以及提出研究问题的基本原理，以及分析数据和总结结果所涉及的批判性思维。培训计划必须培训研究人员制定和编写赠款。培训计划必须教授临床医生统计技能和对临床研究所涉及的法规的理解。为了成为多才多艺的临床研究人员，我们将让我们的临床实习生获得基础科学研究和基础科学研究中涉及的实验室技能的理解。我们为我们的教师招募了有才华的基础科学家和医学科学家。我们的目标是增加这些研究人员之间的对话，以培养能够与临床研究人员和基础科学研究人员合作的翻译研究人员。我们将我们的教师组织成四个综合科学轨道：神经科学和麻醉，重症监护，疼痛和成瘾，血管生物学和生物工程。我们现在提出了第五个轨道，临床研究培训，直接与所有四个科学轨道合作。麻醉系的一名高级研究员领导每一个轨道，每个轨道包括医生科学家和基础科学家。该结构旨在促进富有成效的互动，并在具有共同兴趣的研究人员之间开发项目赠款，同时允许在对麻醉实践重要的不同领域进行培训。与基础科学研究培训计划相比，临床研究培训一直是非正式的，组织较少。因此，该培训计划的任务之一是提供一种结构化，有组织的方法来教授临床研究方法，适用于动态的临床环境。最终目标是培养受训者成为独立的临床研究者，他们将在临床研究设计方法和分析技术方面受到良好的培训，并在学术研究环境中变得富有成效，有助于改善患者结局的发现。我们要求每年4个职位，主要是两年的博士后研究员。我们主要有MD/PhD和PhD，但我们正试图招募更多的临床科学家，他们将成为MD。我们将为他们提供两年的培训。 相关性：医生越来越需要将基本的科学发现带给患者，并证明这些发现实际上改善了患者的预后。在患者身上测试药物和器械需要法规知识、临床试验设计知识以及发现所涉及的科学知识。这项培训补助金将培训医生，使他们能够为患者带来更多的科学发现，并仔细记录这些发现的安全性，有效性和重要性。

DESCRIPTION (provided by applicant): The objectives of this training grant are to ensure that our trainees learn state-of-the-art research techniques, as well as the fundamentals of posing a research question, and the critical thinking involved with analyzing data and summarizing results. A training program must train the researchers to formulate and write grants. A training program must teach clinicians the statistical skills and an understanding of the regulations that are involved in clinical research. To become versatile clinical researchers, we will have our clinical trainees acquire an understanding of basic science research and the laboratory skills involved in basic science research. We have recruited talented basic scientists and physician-scientists for our faculty. Our goal is to increase the dialogue between these groups of researchers to produce translational researchers who are capable of working with both clinical researchers and with basic science researchers. We have organized our faculty into four integrated scientific tracks: Neuroscience and Anesthesia, Critical Care, Pain and Addiction, and Vascular Biology and Bioengineering. We are now proposing a fifth track, Clinical Research Training, that directly collaborates with all the four scientific tracks. A senior researcher in the Department of Anesthesia leads each of these tracks and each track includes physician-scientists and basic scientists. This structure is proposed to foster productive interactions and develop program project grants amongst the researchers with common interests, while allowing training in the diverse areas important to the practice of anesthesia. In contrast to basic science research training programs, clinical research training has been informal and less organized. As a result, one of the missions of this training program is to provide a structured, organized approach to teaching clinical research methods, applicable to the dynamic clinical environment. The ultimate goal is to prepare the trainee to become an independent clinical investigator, who will be well trained in clinical research study design methods and analytical techniques and become productive in an academic research environment, contributing to discoveries that will improve patient outcomes. We request 4 slots per year that will primarily be filled with postdoctoral fellows for two years. We have had mostly MD/PhDs and PhDs but we are attempting to recruit more clinician scientists who will be MDs. We will offer them 2 years of training. Relevance: There is an increased need for physicians to bring basic scientific discoveries to patients, and to prove that these discoveries actually improve patient outcomes. Testing medications and devices in patients requires regulatory knowledge, knowledge regarding clinical trial design, and knowledge about the science involved in the discovery. This training grant will train physicians so that they can bring more scientific discoveries to patients and carefully document the safety, efficacy, and importance of the discoveries.