A FESIBILITY STUDY OF A BESREST ANALOG FOR LUNAR EXPLORATION (JSC/UTMB)

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的目的是进行一项研究，表明使用月球/月球床休息模拟来模拟月球/月球任务是可能的。这项研究试图建立一个真实的情景，以了解宇航员在月球上时月球重力对生理变化的影响。 这项研究可能持续6-8周，包括三个阶段--床前休息阶段、床上休息阶段(包括6天的9.5度仰卧床休息)和床后休息阶段(包括重新调整)。在UTMB前时间(BR-30到BR-4)，Bruce跑步机测试将评估受试者床前休息的有氧健康水平。记录活动和持续时间的每日活动日志将在此期间完成7天。MRI测试将用于测定腿部肌肉容量，一次是在入院UTMB后的睡前休息开始时，一次是在卧床休息结束时。UTMB入院后，在睡前开始时和卧床结束时各进行一次血浆容量检测。舒适性评估日志将记录测试对象在卧床休息阶段每天三次的舒适度。NASA科学家希望获得的信息将决定这项研究能否建立一个真实的情况，以了解宇航员在月球上时月球重力对生理变化的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research is to perform a study that shows it is possible to simulate a lunar/moon mission by using a lunar/moon bed rest analog. This study is trying to establish a real-life situation for understanding the effects of lunar gravity on physiological changes while astronauts are on the moon. Participation in this study may last 6-8 weeks and involves three phases - a before-bed rest phase, a bed rest phase (includes 6 days of bed rest at 9.5-degree of head-up tilt), and an after-bed rest phase (includes reconditioning).During the pre- UTMB time (BR-30 to BR-4) the Bruce Treadmill Test will assess the pre-bed rest level of aerobic fitness of subjects. The Daily Activity Log which records activities and duration will be completed for 7 days during this period. The MRI test will be used to determine leg muscle volumes once at the start of pre Bed-Rest after admission to UTMB and once at the end of Bed Rest. The Plasma Volume test will be performed once at the start of pre Bed-Rest after admission to UTMB and once at the end of Bed Rest. The Comfort Assessment Log will record comfort level of test subjects three times a day during the Bed Rest Phase. NASA scientists hope to get information that will determine if this study can establish a real-life situation for understanding the effects of lunar gravity on physiological changes while astronauts are on the moon.