ENCOURAGING AND STUDYING THE EFFECTS OF EXERCISE ON OVERWEIGHT ADOLESCENTS AT

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 背景：越来越多的超重儿童和青少年对美国的健康构成了重大威胁。虽然疾病控制中心、美国教育部和德克萨斯州卫生部为学校提供了改善体育(PE)的指导方针，但评估这些指导方针的最佳方式尚未确定。因此，他们的实际利益是未知的。 假设：我们的假设是，较新的高中锻炼计划可以帮助逆转超重青少年的心脏异常。 具体目的和程序：在体检和回答问卷后，学生将在参加两门不同的体育课之前和之后进行一些测试。其中一门课程将与目前教授的课程没有什么不同。另一个将是一个新设计的计划，更符合州和国家的指导方针。将进行的测试包括心电图、一种称为心率变异性的心率分析形式，以及心脏超声图(超声心动图)。将抽取一些血液进行血糖、胰岛素、一种名为瘦素的激素和脂肪酸的分析。 实验设计：我们将通过观察在课程开始前获得的测试是否发生有益的变化来确定新的体育课程是否比现在的课程有所改进。 意义：超重的青少年患糖尿病、心脏病和高血压的风险增加。这些问题将显著降低他们的生活质量和预期寿命，并将大大增加医疗保健成本。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Background: The increasing numbers of overweight children and adolescents poses a major threat to America's health. Although the Centers for Disease Control, U.S. Department of Education, and Texas Department of Health provide schools with guidelines to improve their physical education (PE), the best way to evaluate these guidelines is not established. Therefore, their actual benefit is unknown. Hypothesis: Our hypothesis is that newer high school exercise programs can help reverse the heart abnormalities that occur in overweight youngsters. Specific Aims and Procedures: After a physical examination and answering a questionnaire, the students will undergo some testing before and after participate in one of two different physical education courses. One course will be no different from those taught presently. The other will be a newly designed program that is in greater accordance with state and national guidelines. The tests that will be performed include an electrocardiogram (ECG), a form of heart rhythm analysis called heart rate variability, and a heart sonogram (echocardiogram). Some blood will be drawn for analysis of blood sugar, insulin, a hormone called leptin, and fatty acid. Experimental Design: We will determine whether the new PE course is an improvement over the present-day course by seeing if beneficial changes occur in the tests that were obtained before the course began. Significance: Overweight adolescents are at increased risk of developing diabetes, heart disease, and high blood pressure. These problems will significantly decrease their quality of life and life expectancy, and will greatly increase the costs of health care.