TOXICOGENOMICS OF ACETAMINOPHEN HEPATOTOXICITY

对乙酰氨基酚肝毒性的毒理学

• 批准号: 7716810
• 负责人: PAUL B WATKINS
• 金额: $ 3.15万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-02 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7716810
• 关键词: Acetaminophen; Blood; Computer Retrieval of Information on Scientific Projects Database; Dose; Funding; Gene Expression; Grant; Hepatotoxicity; Human; Institution; Purpose; Research; Research Personnel; Resources; Source; Toxicogenomics; United States National Institutes of Health; day; research study; treatment duration

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research study is to see if whether 7 days of treatment with the maximun recommended dose of acetaminophen (4g per day) will produce changes in gene expression in human blood.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项研究的目的是观察用最大推荐剂量的对乙酰氨基酚（每天4克）治疗7天是否会改变人类血液中的基因表达。