课题基金 / 基金详情

PHASE II RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED SAFETY AND PHARMACOKINETIC

PHASE II RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED SAFETY AND PHARMACOKINETIC
II 期随机、双盲、安慰剂对照安全性和药代动力学
批准号：
7716605
负责人：
KRISTI L. WATTERBERG
金额：
$0.83万
依托单位：
UNIVERSITY OF NEW MEXICO
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
项目状态：
已结题
起止时间：
2008-05-01 至 2008-11-30
来源：
https://reporter.nih.gov/project-details/7716605
关键词：
BirthComputer Retrieval of Information on Scientific Projects DatabaseDoseDouble-Blind MethodDrug KineticsFundingGrantInfantInositolInstitutionIntravenousPhasePlacebo ControlPregnancyPurposeRandomizedResearchResearch PersonnelResourcesSafetySourceUnited States National Institutes of Healthrenal tubular reabsorption

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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的目的是： A.测定极低妊娠婴儿出生后立即静脉注射肌醇60或120 mg/kg的单剂量药代动力学。 确定肌醇的药代动力学是线性的还是非线性的，并确定非线性是否可能与可饱和的肾小管重吸收有关。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is: a. Determine the single-dose pharmacokinetics of intravenous inositol given at a dose of either 60 or 120 mg/kg soon after birth to extremely low gestation infants. b. Determine whether the pharmacokinetics of inositol are linar or nonlinear and determine whether nonlinearity may be related to saturable renal tubular reabsorption.
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Adrenal function and adverse CV outcomes at age 6 after extremely preterm birth
Adrenal function and adverse CV outcomes at age 6 after extremely preterm birth
Adrenal function and adverse CV outcomes at age 6 after extremely preterm birth
NEUROIMAGING AND NEURODEVELOPMENTAL OUTCOME: A SECONDARY TO SURFACTANT
  • 批准号：
    8166608
  • 项目类别：
  • 资助金额：
    $0.09万
  • 财政年份：
    2009
  • 负责人：
    KRISTI L. WATTERBERG
  • 依托单位：
    UNIVERSITY OF NEW MEXICO