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COHORT

COHORT
队列
批准号:
7718361
负责人:
RICHARD M. DUBINSKY
金额:
$4.69万
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-04-01 至 2009-03-31

项目摘要

项目成果

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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金, 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 Cohort是亨廷顿研究集团全球研究中心的一项协调研究工作,旨在前瞻性地从亨廷顿病(HD)患者和HD家庭成员中自愿收集数据。来自年度评估的数据将与具有遗传和环境因素的家庭之间的临床特征(表型)联系起来。来自这些关系的知识将更好地告知我们HD的发病和进展,帮助确定HD的潜在干预措施,并有助于规划旨在减缓HD发病的实验性治疗的研究。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. COHORT is a coordinated research effort by Huntington Study Group research centers worldwide to prospectively collect data from consenting individuals who are affected by Huntington's disease (HD) and who are part of an HD family. The data from annual assessments will relate clinical characteristics (phenotypes) between families with genetic and environmental factors. The knowledge from these relationships will better inform us about the onset and progression of HD, help identify potential interventions for HD, and aid in planning research studies of experimental treatments aimed at slowing the onset of HD.
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CLINICAL TRIAL: 2-CARE
COHORT
CLINICAL TRIAL: MEMANTINE IN HUNTINGTON'S DISEASE
PHAROS
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