Molecular studies of the astrocyte reservoir of HIV-1 in the central nervous system
Molecular studies of the astrocyte reservoir of HIV-1 in the central nervous system
批准号:
nhmrc : 603708
负责人:
A/Pr Stuart Turville
金额:
$39.52万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31
中文摘要
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英文摘要
HIV infects the brain causing dementia in 10-20% patients. Strategies aimed at eradicating HIV infection fail to take into account CNS infection. Understanding the way in which HIV enters, infects and replicates in the brain is pivotal in development of drugs to prevent brain infection and dementia. Our studies have shown that HIV infection of the brain involves mechanisms distinct to those observed for blood and other organs. This study seeks to clarify such mechanisms.
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会议论文
Solving delivery of gene therapy for control of Human Immunodeficiency Virus infection
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批准号:nhmrc : GNT1128012
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项目类别:Project Grants
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资助金额:$76.54万
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财政年份:2017
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负责人:A/Pr Stuart Turville
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依托单位:
Solving delivery of gene therapy for control of Human Immunodeficiency Virus infection
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批准号:nhmrc : 1128012
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项目类别:Project Grants
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资助金额:$52.23万
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负责人:A/Pr Stuart Turville
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依托单位:
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批准号:nhmrc : GNT1100771
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项目类别:Project Grants
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资助金额:$63.51万
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财政年份:2016
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负责人:A/Pr Stuart Turville
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依托单位:
Discovery and mechanisms of host cell factors in HIV uncoating
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批准号:nhmrc : 1100771
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项目类别:Project Grants
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资助金额:$43.55万
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财政年份:2016
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负责人:A/Pr Stuart Turville
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依托单位:
HIV-1 transcriptional gene silencing by promoter targeted si/shRNAs: uncovering mechanisms, optimising delivery systems, assessing in vivo efficacy.
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批准号:nhmrc : 1049473
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项目类别:Project Grants
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资助金额:$42.79万
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财政年份:2013
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负责人:A/Pr Stuart Turville
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依托单位:
Regulation of F-actin during HIV spread
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批准号:nhmrc : 1046703
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项目类别:Project Grants
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资助金额:$37.3万
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财政年份:2013
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负责人:A/Pr Stuart Turville
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依托单位:
Dissemmnation of HIV and establishment of cellular reservoirs during transmission
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批准号:nhmrc : 632932
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项目类别:Career Development Fellowships
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资助金额:$26.3万
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财政年份:2010
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负责人:A/Pr Stuart Turville
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依托单位:
HIV assembly, transport, egress and transfer from infected dendritic cells
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批准号:nhmrc : 570917
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项目类别:NHMRC Project Grants
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资助金额:$34.12万
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财政年份:2009
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负责人:A/Pr Stuart Turville
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依托单位:
Kinetics and inhibition of viral transfer from ex vivo derived dendritic cells to CD4 lymphocyte subsets
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批准号:nhmrc : 306708
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项目类别:Early Career Fellowships
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资助金额:$29.74万
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财政年份:2005
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负责人:A/Pr Stuart Turville
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依托单位:
国内基金
海外基金
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批准号:82371528
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项目类别:面上项目
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资助金额:49.00万元
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批准年份:2023
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负责人:李媛
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依托单位:
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批准号:82371307
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项目类别:面上项目
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资助金额:49.00万元
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批准年份:2023
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负责人:汤耀辉
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依托单位: