NICHD Cooperative Multicenter Neonatal Research Network
NICHD 多中心新生儿合作研究网络
基本信息
- 批准号:8451526
- 负责人:
- 金额:$ 28.11万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2006
- 资助国家:美国
- 起止时间:2006-04-05 至 2016-03-31
- 项目状态:已结题
- 来源:
- 关键词:Academic Medical CentersAddressAgricultureApplied GeneticsAreaCessation of lifeClinicalClinical ResearchClinical TrialsClinical Trials DesignCollaborationsCommitCountryDNA LibraryDNA RepositoryDatabasesDiscipline of obstetricsDiseaseEnrollmentEnsureEvaluationFacultyFosteringFundingGeneric DrugsGeneticGenomicsHealthInfantInstitutionMedicineMissionMorbidity - disease rateMulticenter Neonatal Research NetworkMulticenter TrialsNational Institute of Child Health and Human DevelopmentNeonatalNeonatal Intensive CareNeonatologyNeurodevelopmental ImpairmentNewborn InfantOutcomePatientsPediatricsPerinatalPopulationProductivityResearchResearch DesignResearch InfrastructureResearch PersonnelResourcesRoleRuralRural PopulationSafetySamplingSiteTherapeuticTimeUniversitiesVisionWorkbasecareer developmentcritically ill newbornfollow-upmembermortalityneonatepopulation basedpressureprogramsprospectivepublic health relevancesuccesstool
项目摘要
DESCRIPTION (provided by applicant): The University of lowa submits this renewal application for continued participation in the NICHD Cooperative Multicenter Neonatal Research Network (RFA-HD-10-003). We offer five special strengths to the Network. 1. Our NICU's clinical outcomes are superb - among the best in the world. Our VLBW mortality is perennially the lowest in the Neonatal Research Network. With our low mortality and high follow-up rate, we see as many as VLBW infants in follow-up as some much larger Network centers. 2. We have a strong tradition and track record of important contributions in clinical research in neonates and infants. In the obstetrics units and the NICU, we have a robust infrastructure for the conduct and support of clinical research that has contributed to our productivity. 3. We have considerable expertise and resources in the area of genetics, including our Perinatal Research DNA Bank, which was created in 1999. Samples from our DNA Bank and others are being used for research on the genetic influences of neonatal disease. During our first 5 years in the Network, one of our investigators, Dr. Jeff Murray, has worked with others in the Network to apply genetics and genomics approaches on a Network-wide scale, including the application to develop a prospective DNA repository. 4. As the only academic medical center in a largely rural state with an economy based in agriculture, we represent a population that is not otherwise well represented in the NICHD Network. If the results of Network studies are to be generalized to patients throughout the country, this large area of the country should be represented. The University of lowa Network center represents this region and population. 5. We have performed extremely well as a Network center during the past 5 years. We have contributed approximately 1/6 of the new projects submitted in the current funding cycle. Our ELBW mortality rates are the lowest in the Network, and we have the lowest rate of the composite outcome of death or neurodevelopmental impairment. Our follow-up rate is among the highest in the Network. Our patient enrollment in the Generic Database has more than doubled since we added a second site early this year.
描述(由申请人提供):洛瓦大学提交续订申请,以继续参与 NICHD 合作多中心新生儿研究网络 (RFA-HD-10-003)。我们为网络提供五项特殊优势。 1. 我们的新生儿重症监护室 (NICU) 的临床效果非常出色,位居世界前茅。我们的极低出生体重儿死亡率在新生儿研究网络中始终是最低的。由于死亡率低、随访率高,我们发现接受随访的 VLBW 婴儿数量与一些规模大得多的网络中心一样多。 2. 我们在新生儿和婴儿临床研究方面拥有悠久的传统和重要贡献的记录。在产科和新生儿重症监护室,我们拥有强大的基础设施来进行和支持临床研究,这有助于提高我们的生产力。 3. 我们在遗传学领域拥有丰富的专业知识和资源,包括 1999 年创建的围产期研究 DNA 库。我们的 DNA 库和其他库中的样本正用于研究新生儿疾病的遗传影响。在我们加入网络的头 5 年里,我们的一位研究人员 Jeff Murray 博士与网络中的其他人合作,在网络范围内应用遗传学和基因组学方法,包括开发前瞻性 DNA 存储库的应用。 4. 作为经济以农业为主的农村州唯一的学术医疗中心,我们代表的人口在 NICHD 网络中没有得到很好的代表。如果要将网络研究的结果推广到全国各地的患者,则应该代表该国的这一大片地区。洛瓦大学网络中心代表了该地区和人口。 5. 在过去的5年中,我们作为网络中心的表现非常出色。我们贡献了当前资助周期内提交的新项目的约 1/6。我们的 ELBW 死亡率是网络中最低的,而且我们的死亡或神经发育障碍综合结果的发生率也是最低的。我们的跟进率是网络中最高的。自今年年初添加第二个站点以来,我们在通用数据库中的患者注册人数增加了一倍多。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
EDWARD F BELL其他文献
EDWARD F BELL的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('EDWARD F BELL', 18)}}的其他基金
Transfusion-Associated Brain Improvement (TABI) trial - CCC
输血相关大脑改善 (TABI) 试验 - CCC
- 批准号:
8269508 - 财政年份:2012
- 资助金额:
$ 28.11万 - 项目类别:
Transfusion-Associated Brain Improvement (TABI) trial - CCC
输血相关大脑改善 (TABI) 试验 - CCC
- 批准号:
8514715 - 财政年份:2012
- 资助金额:
$ 28.11万 - 项目类别:
Transfusion-Associated Brain Improvement (TABI) trial - CCC
输血相关大脑改善 (TABI) 试验 - CCC
- 批准号:
8849489 - 财政年份:2012
- 资助金额:
$ 28.11万 - 项目类别:
PROCALCITONIN, INTERLEUKIN-10, AND CD64 AS MARKERS OF NEONATAL SEPSIS
降钙素原、白细胞介素 10 和 CD64 作为新生儿败血症的标志物
- 批准号:
7604923 - 财政年份:2007
- 资助金额:
$ 28.11万 - 项目类别:
SURVEY OF OUTCOMES OF VERY LOW BIRTH WEIGHT INFANTS (401-1500 GRAMS) (GDB)
极低出生体重婴儿(401-1500 克)的结果调查 (GDB)
- 批准号:
7604913 - 财政年份:2007
- 资助金额:
$ 28.11万 - 项目类别:
SURFACTANT POSITIVE AIRWAY PRESSURE AND PULSE OXIMETRY TRIAL (SUPPORT)
表面活性剂气道正压和脉搏血氧饱和度试验(支持)
- 批准号:
7604915 - 财政年份:2007
- 资助金额:
$ 28.11万 - 项目类别:
NICHD Cooperative Multicenter Neonatal Research Network
NICHD 多中心新生儿合作研究网络
- 批准号:
8081297 - 财政年份:2006
- 资助金额:
$ 28.11万 - 项目类别:
NICHD Cooperative Multicenter Neonatal Research Network
NICHD 多中心新生儿合作研究网络
- 批准号:
8641710 - 财政年份:2006
- 资助金额:
$ 28.11万 - 项目类别:
相似海外基金
Rational design of rapidly translatable, highly antigenic and novel recombinant immunogens to address deficiencies of current snakebite treatments
合理设计可快速翻译、高抗原性和新型重组免疫原,以解决当前蛇咬伤治疗的缺陷
- 批准号:
MR/S03398X/2 - 财政年份:2024
- 资助金额:
$ 28.11万 - 项目类别:
Fellowship
Re-thinking drug nanocrystals as highly loaded vectors to address key unmet therapeutic challenges
重新思考药物纳米晶体作为高负载载体以解决关键的未满足的治疗挑战
- 批准号:
EP/Y001486/1 - 财政年份:2024
- 资助金额:
$ 28.11万 - 项目类别:
Research Grant
CAREER: FEAST (Food Ecosystems And circularity for Sustainable Transformation) framework to address Hidden Hunger
职业:FEAST(食品生态系统和可持续转型循环)框架解决隐性饥饿
- 批准号:
2338423 - 财政年份:2024
- 资助金额:
$ 28.11万 - 项目类别:
Continuing Grant
Metrology to address ion suppression in multimodal mass spectrometry imaging with application in oncology
计量学解决多模态质谱成像中的离子抑制问题及其在肿瘤学中的应用
- 批准号:
MR/X03657X/1 - 财政年份:2024
- 资助金额:
$ 28.11万 - 项目类别:
Fellowship
CRII: SHF: A Novel Address Translation Architecture for Virtualized Clouds
CRII:SHF:一种用于虚拟化云的新型地址转换架构
- 批准号:
2348066 - 财政年份:2024
- 资助金额:
$ 28.11万 - 项目类别:
Standard Grant
BIORETS: Convergence Research Experiences for Teachers in Synthetic and Systems Biology to Address Challenges in Food, Health, Energy, and Environment
BIORETS:合成和系统生物学教师的融合研究经验,以应对食品、健康、能源和环境方面的挑战
- 批准号:
2341402 - 财政年份:2024
- 资助金额:
$ 28.11万 - 项目类别:
Standard Grant
The Abundance Project: Enhancing Cultural & Green Inclusion in Social Prescribing in Southwest London to Address Ethnic Inequalities in Mental Health
丰富项目:增强文化
- 批准号:
AH/Z505481/1 - 财政年份:2024
- 资助金额:
$ 28.11万 - 项目类别:
Research Grant
ERAMET - Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
ERAMET - 快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
- 批准号:
10107647 - 财政年份:2024
- 资助金额:
$ 28.11万 - 项目类别:
EU-Funded
Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
- 批准号:
10106221 - 财政年份:2024
- 资助金额:
$ 28.11万 - 项目类别:
EU-Funded
Recite: Building Research by Communities to Address Inequities through Expression
背诵:社区开展研究,通过表达解决不平等问题
- 批准号:
AH/Z505341/1 - 财政年份:2024
- 资助金额:
$ 28.11万 - 项目类别:
Research Grant