Research Training in Translational Developmental Neuroscience

描述(由申请人提供)：这是一个新的机构国家研究服务奖的修订申请，以支持纽约大学儿童和青少年精神病学系翻译发展神经科学研究的两年、三年博士后和一年博士后培训，也就是儿童研究中心(CSC)和内森·克莱恩精神病学研究所(NKI)，这两个机构已经为这一明确目的而配置。翻译发展神经科学的新领域将促进广泛学科的整合，通过专注于早期发展阶段来减轻精神疾病的终生负担。博士前实习生将是选择将他们的教育延长一年以进行指导的翻译发展神经科学研究的医学生，他们直接与项目主任或联合主任在他们的实验室工作。博士后实习生将来自儿童和青少年精神病学、儿童心理学、儿科神经病学、发展和行为儿科学、认知神经科学、医学物理学、系统神经科学、神经生理学、应用数学和计算机科学。现有资源包括在药理学和心理社会干预和预防试验、功能、结构和化学神经成像、纵向研究、儿童/青少年精神病理学评估方面的专门知识，以及具有从神经生理学、基础发育神经科学到应用数学、生物统计学、生物医学工程学和生物医学物理学的专业知识的附属院系。研究员与两位主要共同导师密切合作，促进独立翻译研究职业生涯的发展，这些职业将从长凳延伸到床边或从床边延伸到社区。受训者受益于贝尔维尤医院中心、CSC和罗克兰儿童精神病学中心高度多样化的患者群体。该计划的总体目标将继续是提供专注于儿童心理健康问题的优秀研究培训，并推动受训人员在翻译发展神经科学这一新学科中从事富有成效的学术研究事业。相关性：医学在许多领域发展迅速，但大脑科学继续落后，特别是在解决儿童和青少年的情感和行为问题时。我们建议培养一种新型的科学家，通过为完成博士和临床研究的初级科学家提供个性化的指导，为这些重要的挑战带来丰富的视角。

DESCRIPTION (provided by applicant): This is a revised application for a renewed Institutional National Research Service Award to support two- and three-year postdoctoral and one-year predoctoral Traineeships in Translational Developmental Neuroscience Research at the New York University Department of Child & Adolescent Psychiatry, aka Child Study Center (CSC) and the Nathan Kline Institute for Psychiatric Research (NKI) which have been configured for this express purpose. The new field of Translational Developmental Neuroscience will facilitate the integration of a wide range of disciplines to alleviate the lifelong burden of mental illness by focusing on the early developmental stages. Predoctoral trainees will be medical students who choose to extend their education by one year to conduct mentored Translational Developmental Neuroscience research working directly with the Program Director or the Co-Director in their labs. Post-doctoral trainees will be drawn from Child and Adolescent Psychiatry, Child Psychology, Pediatric Neurology, Developmental and Behavioral Pediatrics, Cognitive Neuroscience, Medical Physics, Systems Neuroscience, Neurophysiology, Applied Mathematics, and Computer Science. Available resources include expertise in pharmacological and psychosocial intervention and prevention trials, functional, structural and chemical neuroimaging, longitudinal studies, assessment of child/adolescent psychopathology, and affiliated faculties with expertise that extends from neurophysiology, basic developmental neuroscience to applied mathematics, biostatistics, biomedical engineering and biomedical physics. Research fellows work closely with two primary co-mentors to facilitate the development of independent translational research careers that will extend from the bench-to-bedside or from bedside-to-community. Trainees benefit from highly diverse patient populations at Bellevue Hospital Center, CSC, and the Rockland Children's Psychiatric Center. The overall goals of the program will continue to be to provide excellent research training focused on child mental health problems, and to advance trainees to productive academic research careers in the new discipline of Translational Developmental Neuroscience. RELEVANCE: Medicine is advancing rapidly in many areas, but the science of the brain continues to lag behind, especially when addressing the emotional and behavioral problems of children and adolescents. We propose to train a new type of scientist who will bring a wealth of perspectives to these important challenges by providing individualized mentoring to junior scientists who have completed their doctoral and clinical studies.