2014 Bacterial Cell Surfaces Gordon Research Conference

描述（由申请人提供）：本提案旨在为第21届戈登细菌细胞表面研究会议寻求支持，该会议将于2014年6月22日至27日在佛蒙特州西多佛雪山度假村举行。会议重点关注细菌包膜和表面的生物发生，结构和功能，包括细菌膜，细胞壁，表面附属物和聚合物。本次会议在主题、模型系统和结合生物化学、分子遗传学、结构生物学、生物物理学、成像和建模的方法方面提出了多样化的方案。将有9场会议，主题涉及：1)细胞壁生物发生，2)表面聚合物，外多糖及其分泌，3)细胞区隔化和蛋白质定位，4)运动，表面结构和接触依赖性细胞间活动，5)蛋白质分泌，6)细胞分裂和形态发生，7)包膜应激反应，8)内外膜生物发生，以及9)跨包膜运输。本次会议的目标是：1)通过汇集不同群体的科学家，在方法、专业知识、实验模型和资历方面，展示这些领域最新和最令人兴奋的研究；2)产生新的想法，并促进这一多样化研究群体之间的知识交流；3)为研究生和博士后提供机会，以简短的谈话或演讲形式展示他们的工作

DESCRIPTION (provided by applicant): This proposal seeks support for the 21st Gordon Research Conference on Bacterial Cell Surfaces, which will be held June 22-27, 2014 at Mount Snow Resort, West Dover, VT. The meeting focuses on the biogenesis, structure and function of bacterial envelopes and surfaces, including bacterial membranes, cell walls, and surface appendages and polymers. This conference presents a diverse program in topics, model systems, and approaches combining biochemistry, molecular genetics, structural biology, biophysics, imaging and modeling. There will be 9 sessions on topics related to 1) cell wall biogenesis, 2) surface polymers, exopolysaccharides and their secretion, 3) cell compartmentalization and protein localization, 4) motility, surface structures and contact-dependent intercellular activities, 5) protein secretion, 6) cell division and morphogenesis, 7) envelope stress responses, 8) inner and outer membrane biogenesis, and 9) transport across the cell envelope. The objectives of this conference are to: 1) present the latest and most exciting research in these areas by bringing together a diverse group of scientists with respect to approaches, expertise, experimental model, and seniority; 2) generate new ideas and stimulate intellectual exchange between this diverse group of investigators; and 3) provide opportunities for graduate students and postdoctoral fellows to present their work in short-talk or poster format and to interact with leaders in the field. The traditional format of the Gordon Research Conferences, with programmed discussion sessions and opportunities for informal gatherings in the afternoons and evenings, conveys a collegial atmosphere where interactions between attendees are easily attained. Although the science presented is basic in nature, the topics of this multifaceted conference are of practical interest to the biomedical community in the areas of pathogenesis, antibiotic action and resistance, and host-microbe interactions, as many of these phenomena involve processes at the level of membranes, cell walls and cell surface. This conference will thus provide a platform for future developments of vaccine and antibacterial strategies.