Administrative Core

行政核心

• 批准号: 10310698
• 负责人: JEFFREY L WEINER
• 金额: $ 14.65万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-12-10 至 2022-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10310698
• 关键词: Address; Alcohol consumption; Alcohol dependence; Alcohols; Awareness; Behavior; Behavioral; Behavioral Mechanisms; Biometry; Communities; Complement; Education and Outreach; Ensure; Environment; Faculty; Funding; Goals; Grant; Health Personnel; Healthcare Systems; Human; Individual; Infrastructure; Institution; Intervention; Leadership; Learning; Medical center; Modeling; Monkeys; National Institute on Alcohol Abuse and Alcoholism; Neurobiology; Pilot Projects; Population; Postdoctoral Fellow; Public Health; Reproducibility; Research; Research Personnel; Research Project Grants; Research Support; Research Training; Risk; Rodent; Students; Testing; Training Activity; Training Programs; Translational Research; Triad Acrylic Resin; Work; addiction; alcohol abuse therapy; alcohol research; alcohol use disorder; behavioral study; experience; forest; human subject; innovation; insight; interdisciplinary approach; medical schools; neuroadaptation; neurobiological mechanism; nonhuman primate; novel; novel therapeutic intervention; organizational structure; outreach; relating to nervous system; resilience; success; training opportunity; translational study

PROJECT SUMMARY The central goal of the Wake Forest Translational Alcohol Research Center (WF-TARC) is to employ rodent, non-human primate and human subjects to study behavioral and neurobiological substrates associated with vulnerability (and resilience) to alcohol use disorder (AUD). The Administrative Core will provide the organizational infrastructure and support needed to ensure that the WF-TARC functions optimally and accomplishes all its goals and objectives. A strong leadership team will oversee WF-TARC research progress. They will be advised by External and Internal Advisory Boards comprised of outstanding researchers with expertise in translational programmatic alcohol research. The major goals of the Administrative Core will be to promote scientific integration across projects, provide biostatistical support to WF-TARC investigators, enhance scientific rigor and reproducibility, seek out synergistic opportunities with other WFSM addiction- related Centers and promote education and outreach related to the scientific aims of the WF-TARC. These goals will be accomplished through a detailed organizational structure that includes a Steering Committee, a Biostatistical Support Unit, an Education and Outreach Committee, and a highly experienced administrative support team. The Administrative Core will also provide support for a Pilot Project Core that will support new and innovative translational alcohol research initiatives to complement and expand the scope of alcohol research supported by this Center. Collectively, this Core will provide the administrative leadership and infrastructure to best facilitate the integrated translational WF-TARC research projects and pilots, create new translational alcohol research opportunities at WFSM, enhance the translational alcohol research training environment at our institution and support ongoing and new alcohol-related outreach activities throughout the Piedmont Triad region.

项目摘要 维克森林转化酒精研究中心（WF-TARC）的中心目标是利用啮齿动物， 非人灵长类动物和人类受试者研究与以下相关的行为和神经生物学底物： 酒精使用障碍（AUD）的脆弱性（和弹性）。行政核心将提供 确保WF-TARC最佳运作所需的组织基础设施和支持， 实现其所有目标和目的。一个强有力的领导团队将监督WF-TARC的研究进展。 他们将由外部和内部咨询委员会提供咨询，该委员会由杰出的研究人员组成， 在翻译计划酒精研究的专业知识。行政核心的主要目标是 促进跨项目的科学整合，为WF-TARC调查人员提供生物统计支持， 提高科学的严谨性和可重复性，寻求与其他WFSM成瘾的协同机会- 与相关中心合作，促进与世界基金会-TARC科学目标有关的教育和外联。这些 目标将通过一个详细的组织结构来实现，其中包括一个指导委员会，一个 生物统计支助股、一个教育和外联委员会以及一个经验丰富的行政管理人员。 支持团队。行政核心还将为一个试点项目核心提供支持， 和创新的翻译酒精研究倡议，以补充和扩大酒精的范围 本中心支持的研究。总的来说，这一核心将提供行政领导， 基础设施，以最好地促进综合翻译WF-TARC研究项目和试点，创造新的 WFSM的转化酒精研究机会，加强转化酒精研究培训 环境在我们的机构和支持正在进行的和新的酒精相关的推广活动，在整个 皮埃蒙特三合会地区。