National Alcohol Surveys: Advancing Epidemiologic Analyses of 21st Century Drinking

全国酒精调查：推进 21 世纪饮酒的流行病学分析

• 批准号: 10359039
• 负责人: Priscilla Martinez
• 金额: $ 34.99万
• 依托单位: PUBLIC HEALTH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1981
• 资助国家: 美国
• 起止时间: 1981-07-01 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10359039
• 关键词: Address; Adult; Age; Alcohol abuse; Alcohol consumption; Alcoholic beverage heavy drinker; Alcohols; Anxiety; Archives; Area; Back; Beverages; Biological; Black Populations; Blood; Blood Tests; Cannabis; Censuses; Cessation of life; Characteristics; Collection; Communities; Consumption; Data; Data Analyses; Data Collection; Educational Background; Elderly; Epidemiology; Ethnic Origin; Ethnic group; Future; Gender; Health; Heavy Drinking; Individual; Inflammation; Interdisciplinary Study; Internet; Knowledge; Latino Population; Learning; Legal; Link; Longitudinal trends; Marijuana; Measures; Mediator of activation protein; Mental Depression; Mental Health; Methodology; Methods; Modeling; Modernization; Monitor; Morbidity - disease rate; NR4A1 gene; Neighborhoods; Online Systems; Opioid; Outcome; Pattern; Pharmaceutical Preparations; Policies; Population; Positioning Attribute; Probability; Race; Research; Research Personnel; Respondent; Risk; Risk Factors; Sales; Sampling; Series; Source; Spottings; Standardization; Subgroup; Survey Methodology; Surveys; Symptoms; Taxes; Techniques; Testing; Time; Weight; Woman; alcohol effect; alcohol epidemiology; alcohol measurement; alcohol related problem; alcohol research; alcohol risk; alcohol use disorder; base; burden of illness; cohort; design; drinking; falls; gender difference; group intervention; hazardous drinking; improved; inflammatory marker; innovation; low socioeconomic status; marijuana legalization; marijuana use; middle age; mortality; neighborhood disadvantage; opioid epidemic; perceived stress; pilot test; population survey; preventive intervention; psychological distress; public health relevance; public policy on alcohol; racial and ethnic; racial and ethnic disparities; recruit; sociodemographics; socioeconomic disparity; socioeconomics; trend; trend analysis

ABSTRACT: National Alcohol Surveys: Advancing Epidemiologic Analyses of 21st Century Drinking Hazardous alcohol use remains one of the most common preventable causes of morbidity and mortality in the US and it manifests major racial/ethnic and other disparities. Nationally representative surveys repeated over time provide a means to advance survey methods, monitor trends in alcohol use overall and in sub-groups, and investigate timely health topics related to alcohol use. The Alcohol Research Group and its Center have conducted a series of National Alcohol Surveys (NAS) for forty years, and are proposing in this Project to conduct the 15th edition of the NAS in 2023-2024 (termed N15). Through the implementation of the N15 we will respond to challenges to modern-day survey research by employing a multi-mode, adaptive survey design. This will include a fully web-based survey using address-based sampling, and probability and non-probability web panels. Further, this will be the first NAS to include biosample collection using dried blood spots (DBS). Including an additional NAS in the series will expand the trend data available for framing recent changes in alcohol consumption patterns, which is also essential for age-period-cohort models for understanding components of these trends. With NAS series data from 2000-2020 we propose to evaluate racial/ethnic and socioeconomic disparities in alcohol use and alcohol problems, and risk relationships between alcohol use patterns and problems using causal inference methods including instrumental variables based on alcohol tax estimates and other policy measures. Such methods have yet to be applied to the study of disparities in alcohol-related problems. Capitalizing on the expanded trends data, we propose to examine trends for total and beverage- specific alcohol volume, alcohol use disorder, and co-use of alcohol with marijuana and other drugs from 1979 or 1984, dependent on the availability of measures, to 2024 with age-period-cohort decompositions. Alcohol and drug co-use, particularly cannabis, is especially timely given the legalization of recreational marijuana use in many states and the ongoing opioid crisis. Psychological distress (PD) is a likely driver of the opioid crisis and “deaths of despair”. Recent NAS editions have included measures of PD, a common problem for which alcohol use is a known risk factor. However, less well understood are the individual- and environmental-level moderators and biological mediators of this relationship. Collecting DBS samples will enable the study of inflammation as a biological mediator of the relationship between alcohol use and PD, which could inform future research and prevention interventions. Further, a better understanding of the moderators of the relationship between alcohol use and PD, from individual- to community-level characteristics, could help to prioritize groups to receive prevention interventions. In summary, this project proposes data collection and analyses that can advance both methodological issues and substantive research questions with the aim of better understanding and addressing 21st century drinking and its trends, correlates and consequences.

摘要：国家酒精调查：21世纪饮酒的流行病学分析 危险饮酒仍然是最常见的可预防原因之一 我们和它表现出主要的种族/种族和其他差异。全国代表性的调查重复 时间提供了一种方法来推进调查方法，监测整体和子组中酒精饮酒的趋势以及 调查与饮酒有关的及时健康主题。酒精研究小组及其中心有 进行了一系列国家酒精调查（NAS）已有40年了，并提议该项目进行 NAS在2023 - 2024年的第15版（称为N15）。通过实施N15，我们将回应 通过采用多模式的自适应调查设计来挑战现代调查研究。这会 使用基于地址的采样以及概率和非概率网络面板包括一个完全基于网络的调查。 此外，这将是第一个使用干血点（DBS）收集生物样品的NA。包括一个 该系列中的其他NA将扩大可用于构架酒精最新变化的趋势数据 消费模式，这对于了解年龄 - 周期性的模型也至关重要 这些趋势。通过2000 - 2020年的NAS系列数据，我们建议评估种族/种族和社会经济 酒精使用和酒精问题的差异，以及酒精使用模式之间的风险关系和 使用因果推理方法的问题，包括基于酒精税估计的工具变量和 其他政策措施。此类方法尚未应用于与酒精相关的差异的研究 问题。利用扩展的趋势数据，我们建议检查总和卧室的趋势 - 从1979年起，特定的酒精量，酒精使用障碍以及与大麻和其他药物共同使用 或1984年，取决于度量的可用性，到2024年，随着年龄的周期性分解。酒精和 鉴于在休闲大麻合法化中，毒品共同使用，尤其是大麻，特别及时 许多州和正在进行的阿片类药物危机。心理困扰（PD）可能是阿片类药物危机和 “绝望的死亡”。 NAS最近的版本包括PD的措施，这是一个常见的问题 使用是已知的危险因素。但是，个人和环境级别的主持人不太了解 和这种关系的生物介体。收集DBS样品将使炎症作为一种 酒精使用与PD之间关系的生物学调解人，这可能为未来的研究和 预防干预措施。此外，对酒精之间关系的主持人有更好的理解 使用和PD，从个人到社区级的特征，可以帮助团体优先级 预防干预措施。总而言之，该项目提出数据收集和分析可以推进两者 方法论问题和实质性研究问题，目的是更好地理解和解决 21世纪的饮酒及其趋势，相关和后果。