Postdoctoral Training in Cardiometabolic Science

项目摘要/摘要 这一创新的T32建议满足了培养新的博士后科学家成为 心脏代谢科学领域的领军人物。在心血管疾病和新陈代谢的交叉点 疾病是过度的发病率和死亡率，最好的解决办法是成功的科学家和综合研究 在这些地区。我们的建议解决了3个方面的培训需求：第一，这些科学家需要培训 来自心血管和新陈代谢研究人员。第二，培训必须在以下环境中进行 成功导师之间的相关跨学科合作已经在进行中。第三， 男性和女性都必须积极追求女科学家的进步，以最大限度地发挥才华 游泳池。薛博士和拉曼博士是国际公认的糖尿病/新陈代谢和 心血管医学，汇聚了一个由NIH资助的心血管和新陈代谢团队 俄亥俄州立大学(OSU)的研究人员，采用双重导师制培训设计，为学员提供 必要的跨学科科学和专业指导。俄亥俄州立大学心脏代谢环境 培训是无与伦比的，戴维斯心肺研究所和糖尿病研究所的教员 新陈代谢研究中心(薛主任)从事NHLBI资助的基础、翻译、 和临床学科。为了推动女性在心脏代谢科学方面的进步，这款T32利用了许多 俄亥俄州立大学的项目包括一项针对心血管科学多样性的博士前T32项目，该项目由 调查员拉斐尔-福特尼博士。教师导师的选择是专门针对他们富有成效的职业生涯 记录和研究出版物生产力和NIH奖励他们的受训者的成功。我们将注册2个新的 每年博士后实习生，为期两年，第三名由俄亥俄州立大学医学院支持 (COM，PhD)和内科(DOIM，MD或MD-PhD)资助。认出那个医生 由于研究时间不足，科学家获得第一个K奖的竞争力可能会降低。 由DOIM资助的博士后培训是为医生实习生提供的。俄亥俄州立大学成功地吸引了 医生愿意在研究培训上投入必要的时间，这一点从像The 医师科学家培训计划(PSTP)。这款T32的亮点包括明确的里程碑、开发 心脏代谢科学的正式课程，使该项目成为一门独立的学科， 监管会议，以及跨多个机构层面的有效努力，以改变文化 妇女在心脏代谢科学方面的进步。个性化的发展计划通过指标进行评估 例如出版物、职业发展奖、完成课程和研讨会以及过渡到 研究和学术生涯。我们的师资、基础设施、领导力、实习生队伍和独特的科学关注点 将培养男性和女性心脏代谢科学家，并填补关键的博士后培训缺口。

PROJECT SUMMARY/ABSTRACT This innovative T32 proposal addresses a critical need to train emerging postdoctoral scientists to become leaders in cardiometabolic science. At the intersection between cardiovascular disease and metabolic disorders lies excess morbidity and mortality, best addressed by successful scientists and research integrated in these areas. Our proposal addresses 3 aspects of the training need: First, these scientists require training from both cardiovascular and metabolic researchers. Second, training must occur in an environment where relevant interdisciplinary collaborations among successful mentors are already underway. Third, the advancement of women scientists must be actively pursued by both men and women to maximize the talent pool. Drs. Hsueh and Raman, internationally-recognized, established investigators in diabetes/metabolism and cardiovascular medicine, have brought together a team of NIH-funded cardiovascular and metabolic researchers at the Ohio State University (OSU), with a dual mentorship training design that gives trainees essential cross-disciplinary scientific and professional guidance. OSU’s environment for cardiometabolic training is unparalleled, with faculty in the Davis Heart and Lung Research Institute and the Diabetes and Metabolism Research Center (Hsueh, Director) engaged in NHLBI-funded research across basic, translational, and clinical disciplines. To advance women in cardiometabolic science, this T32 leverages a number of programs across OSU including a predoctoral T32 program for diversity in cardiovascular science led by co- investigator Dr. Rafael-Fortney. Faculty mentors have been chosen specifically both for their productive track records and for research publication productivity and NIH award success of their trainees. We will enroll 2 new postdoctoral trainees per year for 2 years’ training, with a 3rd slot supported by OSU College of Medicine (COM, PhD) and Department of Internal Medicine (DOIM, MD or MD-PhD) funding. Recognizing that physician scientists may be less competitive for a first K award due to inadequate research time, a third year of postdoctoral training, covered by DOIM funds, is provided for physician trainees. OSU’s success in attracting physicians willing to invest the needed time in research training is evident by such successful entities as the Physician Scientist Training Program (PSTP). Highlights of this T32 include clear milestones, development of a formal course in Cardiometabolic Science that distinguishes this program as an independent discipline, regulatory sessions, and effective efforts across many institutional layers to change culture towards advancement of women in cardiometabolic science. Individualized development plans are assessed by metrics such as publications, career development awards, completion of coursework and workshop, and transition to research and academic careers. Our faculty, infrastructure, leadership, trainee pool, and unique scientific focus will deliver male and female cardiometabolic scientists and fill a critical postdoctoral training gap.