Pilot Research Project Core E

项目概要-先导研究项目核心E CWRU药物使用对艾滋病毒试点研究影响卓越中心 项目核心刺激创新的兴奋剂发起的物质使用相关的临床， 翻译和基础科学研究活动。试点研究项目的核心将是 专注于卓越中心的所有辅导和培训活动。重点项目 由核心资助的是三个年度试点赠款金65,000美元，以早期职业生涯和下， 医学代表（URiM）研究者或更高级的研究者， 鼓励进行物质使用研究。这些试点奖励将与一对一- 一个指导计划，旨在提高我们的初级和URiM教师的竞争力， 联邦赠款。凯斯西储大学和该中心的项目主任 在支持初级和URiM调查员推进其职业生涯方面具有丰富的经验。 自2008年以来，CWRU医学院在NIH的支持下，已投资1，183，068美元 在其指导科学家试点赠款。这些获奖者获得了19，423，434美元的研究经费 由于他们的奖励或16.4倍的投资回报的资金。CWRU中心 卓越试点项目核心将努力匹配和超越这一记录，并开发新的 物质使用研究领域的研究人员。这些试验计划的申请人和获奖者 项目奖励和URiM调查员将被要求参加一对一的指导 计划，由核心组织。我们的机构，通过战略投资基金，还将 通过提供匹配的65，000美元种子资金，为CWRU卓越中心提供支持 第四届年度试点奖，其中初级和URiM教师发挥主导作用，并投资 35，000美元用于促进中心增长和核心利用率，并为以下人员提供差旅和其他支持 初级和任职人数不足的调查员。虽然试点奖励花费NIH资金来支持 我们的战略投资基金是新调查员的单一调查员项目，该基金专门 利用机构资源，支持包括杰出青年和URiM在内的团队 调查员发挥主导作用，还包括常设调查员。一个完整的承诺， 已向该计划提供了50万美元的战略投资基金。的具体目标 核心内容如下： ·开展响应性试点研究资助计划，加速初级和URiM 教师发展，并鼓励建立调查人员扩展到物质 利用研究。 ·识别，指导和支持下一代物质使用调查员。 ·培训和支持物质使用研究人员规划和开展 道德健全，严谨，负责任地进行研究。

Project Summary - Pilot Research Project Core E The CWRU Center for Excellence on the Impact of Substance Use on HIV Pilot Research Project Core stimulates innovative investigator-initiated Substance use-related clinical, translational, and basic science research activities. The Pilot Research Project Core will be the focus for all of the mentoring and training activities of the Center for Excellence. The key program funded by the Core is the award of three annual pilot grants of $65,000 to early-career and Under- Represented in Medicine (URiM) investigators or more senior investigators who will be encouraged to pursue research in Substance Use. These pilot awards will be linked to one-on- one mentoring programs designed to enhance our junior and URiM faculty’s competitiveness for federal grants. Case Western Reserve University and the Program Director of this Center have significant experience in supporting junior and URiM investigators in advancing their careers. Since 2008, the CWRU School of Medicine, with support from the NIH, has invested $1,183,068 in its Mentored Scientist Pilot Grants. These awardees have received $19,423,434 in research funding as a result of their awards or a 16.4-fold return on investment. The CWRU Center for Excellence Pilot Project Core will strive to match and exceed this record and develop new investigators in the field of Substance Use research. Both applicants and awardees of these Pilot Project Awards and URiM investigators will be asked to participate in a one-on-one mentoring program, organized by the Core. Our institution, through the Strategic Investment Fund, will also provide support for this CWRU Center for Excellence by providing matching $65,000 seed funding for a fourth annual Pilot Award in which junior and URiM faculty take a leading role and invest $35,000 to promote Center growth and Core utilization and provide travel and other support for junior and underrepresented investigators. While the pilot awards expend NIH funds to support single investigator projects by new investigators, our Strategic Investment Fund, which exclusively uses institutional resources, supports teams that include outstanding young and URiM investigators in a leading role and also include established investigators. A total commitment from the Strategic Investment Fund for $500,000 has been made to this program. The specific aims of the Core are as follows: • Conduct responsive Pilot Research Grant programs that accelerate junior and URiM faculty development and encourage established investigators to expand into Substance use research. • Identify, mentor, and support the next generation of Substance Use investigators. • Train and provide support to Substance Use researchers in the planning and conduct of ethically sound, rigorous, and responsibly conducted research.