Pilot Research Project Core E

项目摘要-试点研究项目核心E CWRU物质使用对艾滋病毒先导研究的影响卓越中心 Project Core刺激由研究人员发起的与药物使用相关的临床创新， 翻译和基础科学研究活动。试点研究项目的核心将是 专注于卓越中心的所有指导和培训活动。关键计划 核心基金资助的是三笔每年65,000美元的试点补助金，发放给职业生涯初期和以下人员-- 代表医学(URIM)调查人员或更高级的调查人员 鼓励从事物质使用方面的研究。这些试点奖项将与一对一相关联 One指导计划旨在提高我们初级教师和URIM教师的竞争力 联邦拨款。凯斯西部储备大学和该中心的项目主任 在支持初级和URIM调查人员职业发展方面有丰富的经验。 自2008年以来，CWRU医学院在美国国立卫生研究院的支持下，已投资1,183,068美元 在其指导的科学家飞行员补助金中。这些获奖者获得了19,423,434美元的研究 由于他们的奖励或16.4倍的投资回报而获得资金。CWRU中心 卓越先导项目芯将努力追平并超越这一纪录，发展新的 物质使用研究领域的调查人员。这些试点的申请者和获奖者都是 项目奖和URIM调查人员将被要求参加一对一的指导 计划，由核心组织。我们的机构通过战略投资基金，还将 通过提供匹配的65,000美元种子资金，为CWRU卓越中心提供支持 第四个年度飞行员奖，初级和URIM教职员工在其中发挥主导作用并投资 35,000美元，用于促进中心增长和核心利用率，并为以下项目提供差旅和其他支持 初级调查人员和代表性不足的调查人员。虽然试点奖项花费了NIH的资金来支持 单人调查员项目由新调查员，我们的战略投资基金，它独家 利用机构资源，支持包括优秀年轻人和乌里姆在内的团队 调查人员发挥主导作用，还包括老牌调查人员。来自中国的全部承诺 已为该计划设立了50万美元的战略投资基金。的具体目标 核心内容如下： ·实施响应性试点研究资助计划，加速初级和URIM 教师发展和鼓励老牌研究人员深入研究实质性问题 利用研究。 ·确定、指导和支持下一代药物使用调查人员。 ·培训和支持物质使用研究人员规划和实施 道德健全，严谨，负责任地进行研究。

Project Summary - Pilot Research Project Core E The CWRU Center for Excellence on the Impact of Substance Use on HIV Pilot Research Project Core stimulates innovative investigator-initiated Substance use-related clinical, translational, and basic science research activities. The Pilot Research Project Core will be the focus for all of the mentoring and training activities of the Center for Excellence. The key program funded by the Core is the award of three annual pilot grants of $65,000 to early-career and Under- Represented in Medicine (URiM) investigators or more senior investigators who will be encouraged to pursue research in Substance Use. These pilot awards will be linked to one-on- one mentoring programs designed to enhance our junior and URiM faculty’s competitiveness for federal grants. Case Western Reserve University and the Program Director of this Center have significant experience in supporting junior and URiM investigators in advancing their careers. Since 2008, the CWRU School of Medicine, with support from the NIH, has invested $1,183,068 in its Mentored Scientist Pilot Grants. These awardees have received $19,423,434 in research funding as a result of their awards or a 16.4-fold return on investment. The CWRU Center for Excellence Pilot Project Core will strive to match and exceed this record and develop new investigators in the field of Substance Use research. Both applicants and awardees of these Pilot Project Awards and URiM investigators will be asked to participate in a one-on-one mentoring program, organized by the Core. Our institution, through the Strategic Investment Fund, will also provide support for this CWRU Center for Excellence by providing matching $65,000 seed funding for a fourth annual Pilot Award in which junior and URiM faculty take a leading role and invest $35,000 to promote Center growth and Core utilization and provide travel and other support for junior and underrepresented investigators. While the pilot awards expend NIH funds to support single investigator projects by new investigators, our Strategic Investment Fund, which exclusively uses institutional resources, supports teams that include outstanding young and URiM investigators in a leading role and also include established investigators. A total commitment from the Strategic Investment Fund for $500,000 has been made to this program. The specific aims of the Core are as follows: • Conduct responsive Pilot Research Grant programs that accelerate junior and URiM faculty development and encourage established investigators to expand into Substance use research. • Identify, mentor, and support the next generation of Substance Use investigators. • Train and provide support to Substance Use researchers in the planning and conduct of ethically sound, rigorous, and responsibly conducted research.