Pilot Project Program

试点项目计划

• 批准号: 10414549
• 负责人: IAN D MENG
• 金额: $ 26.03万
• 依托单位: UNIVERSITY OF NEW ENGLAND
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10414549
• 关键词: Advisory Committees; Applications Grants; Appointment; Award; Behavior; Budgets; Centers of Research Excellence; Collaborations; Core Facility; Data; Development Plans; Direct Costs; Drosophila genus; Eligibility Determination; Ensure; Environment; Extramural Activities; Faculty; Foundations; Funding; Funding Agency; Future; Gene Targeting; Goals; Grant; Guidelines; Histology; Home; Image; Individual; Injury; Institution; Lead; Letters; Maine; Medical center; Mentors; Modeling; National Institute of General Medical Sciences; New England; New Hampshire; Pain; Pain Research; Persons; Phase; Pilot Projects; Policies; Postdoctoral Fellow; Prevention; Procedures; Process; Program Development; Progress Reports; Publications; Recommendation; Research; Research Institute; Research Personnel; Research Proposals; Review Committee; Scientific Advances and Accomplishments; Seeds; Sensory; Services; Strategic Planning; Study Section; Teacher Professional Development; Therapeutic Intervention; Time; TimeLine; Training; Training Support; United States National Institutes of Health; Universities; Update; Vocational Guidance; Wages; Work; base; career; chemotherapy induced neuropathy; data submission; experience; faculty research; graduate student; gut microbiome; industry partner; inflammatory pain; innovation; meetings; novel; programs; recruit; senior faculty; symposium; voucher

The Pilot Project Program will continue to be a critical component of the COBRE, ensuring the long-term sustainability of both the Behavior Core and the Histology and Imaging Core. Sustainability of these Cores will require continued internal use, but also a strong regional user base from academic institutions and industry partners. To accomplish this, the Pilot Project Program will solicit proposals from research faculty at both UNE and its Northern New England partner institutions (Maine Medical Center Research Institute, Maine INBRE institutions, and the University of New Hampshire), increasing the external user base for the Cores. The Pilot Project Program will provide a maximum of 2-years of funding for early-stage projects to generate preliminary data that have the best chance for obtaining extramural research dollars. With the solicitation of proposals from outside of UNE, funding priorities for the Pilot Project Program will no longer be restricted to pain research but will be expanded to include any projects that utilize the COBRE research cores. Awarding of pilot project grants will be a competitive process, with new and early-stage investigators being given priority over more senior faculty, and with project innovation and research core utilization being weighed heavily. The pilot project program from COBRE Phases 1 and 2 was highly successful, funding 14 pilot projects that have so far led to 8 new grant awards (three R15, one R01, two NIH sub-awards, and two foundation grants), with an additional five grant applications still pending or in the process of revision. The Administrative Core will implement the Pilot Project Program through the following Specific Aims. Aim 1 will solicit, review, and select highly meritorious proposals for funding. Proposals will be evaluated for their scientific strength (Significance, Innovation, and Approach), as well as investigator and environment strengths. The scientific review committee will be composed of both experienced and early-stage investigators, chaired by the COBRE Program Coordinator, mirroring NIH study section procedures. A secondary review of this committee’s recommendations will be completed by the External Advisory Committee (EAC) and COBRE Director before funding decisions are made. In Aim 2, the Administrative Core will provide oversight and evaluate the progress of all pilot project awardees. Pilot Project Leaders will receive a post-award orientation from the COBRE Director, as well as budget support from the COBRE Program Manager, with projects needing to be in full compliance with all applicable NIH policies. Scientific progress will be evaluated quarterly by the mentor(s) of the Pilot Project Leader and the Administrative Core, and annually by the EAC. The Administrative Core in Aim 3 will provide Pilot Project Leaders with career and research guidance through a faculty development program that utilizes trained, formal mentor(s) for both research and career guidance, in addition to formal in-person or asynchronous faculty development sessions. As Pilot Project Leaders may be non-UNE faculty, the Administrative Core will work their home institutions to recruit mentors and ensure that our faculty development content is congruent with their home institutions.

试点项目计划将继续成为 COBRE 的重要组成部分，确保项目的长期可持续性 行为核心以及组织学和成像核心。这些核心的可持续性将需要持续的内部 使用，还包括来自学术机构和行业合作伙伴的强大区域用户群。为了实现这一目标，飞行员 项目计划将向新英格兰大学及其北新英格兰合作伙伴的研究人员征求建议 机构（缅因州医学中心研究所、缅因州 INBRE 机构和新罕布什尔大学）， 增加核心的外部用户群。试点项目计划将提供最长2年的资助 用于早期项目生成初步数据，这些数据最有可能获得外部研究资金。 随着UNE外部提案的征集，试点项目计划的资助优先事项将不再是 仅限于疼痛研究，但将扩展到包括利用 COBRE 研究核心的任何项目。颁奖 试点项目拨款将是一个竞争过程，新的和早期的研究人员将优先于更多的研究人员 资深师资，项目创新和研究核心利用受到重视。试点项目计划 COBRE 的第一阶段和第二阶段非常成功，资助了 14 个试点项目，迄今为止已获得 8 项新的资助 （三项 R15、一项 R01、两项 NIH 子奖项和两项基金会拨款），还有另外五项拨款申请 待定或正在修订中。行政核心将通过以下方式实施试点项目计划： 遵循具体目标。目标 1 将征求、审查并选择非常有价值的资助提案。提案将 评估其科学实力（意义、创新和方法）以及研究者和环境 的优势。科学审查委员会将由经验丰富的和早期研究人员组成，主席为 COBRE 项目协调员，反映 NIH 研究部门的程序。对该委员会的二次审查 建议将由外部咨询委员会 (EAC) 和 COBRE 主任在资助前完成 做出决定。在目标 2 中，行政核心将监督并评估所有试点项目的进展情况 获奖者。试点项目负责人将获得 COBRE 总监的获奖后指导以及预算支持 来自 COBRE 项目经理，项目需要完全符合所有适用的 NIH 政策。 试点项目负责人和行政核心的导师将每季度评估科学进展， 每年由 EAC 进行。目标 3 中的行政核心将为试点项目领导者提供职业和研究机会 通过教师发展计划提供指导，该计划利用经过培训的正式导师进行研究和职业生涯 除了正式的面对面或异步教师发展会议之外，还提供指导。作为试点项目的领导者可能是 对于非UNE教职人员，行政核心将与他们所在的机构合作招募导师，并确保我们的教职人员 发展内容与其所在机构一致。