Predoctoral Training in Pharmacological Sciences

项目摘要 这是一个新的T32拨款申请，寻求对药理学(TIPS)培训的支持，地址为 威尔康奈尔研究生院(WCGS)。如果获奖，该赠款将扩大对非常成功的活跃分子的支持 T32博士前培训计划，目前的资金定于2021年6月30日结束。我们的TIPS计划是感兴趣的 部门和机构间，由33名优秀的教师导师组成，来自威尔康奈尔大学 医学和纪念斯隆-凯特琳癌症中心。我们提供了非常丰富的研究 训练环境，包括最先进的仪器和核心设施，宽敞的空间 分配给TIPS计划，并继续致力于招聘最聪明和最好的新教师。 我们的机构做出了前所未有的承诺，以发展他们的生物医学研究项目， 在过去15年里，该公司通过慈善事业筹集了30亿美元，用于新建筑和教师发展。 参与的教职员工是一群具有凝聚力的世界级调查人员，他们拥有充满活力的持续研究和 培养早期科学带头人和学者的坚实记录。我们是敬业的导师和生物医学 拥有实验室的研究人员每年平均获得140万美元的研究支持。正式的导师培训是 对我们所有的教职员工负有义务，以及对教职员工和招生委员会进行隐性偏见培训。 现有教职员工22人，协会会员4人。教授和5名助理教授，并制定了协议 用于添加和删除培训教员。该计划的一个主要重点是分享 与学员一起发现发现的兴奋，培养学生的批判性推理能力，并向学生灌输 所有必要的技能，以满足他们对培训提供的多样化职业机会的抱负 我们提供。值得注意的是，97%的博士毕业生在过去10年里继续从事研究或 与研究相关的职业。我们的教师导师高度合作，但具有不同的研究兴趣- 为学员提供广泛的培训机会，包括转化型生物医学、 神经药理学、癌症生物学、细胞信号、新陈代谢、化学生物学、合成化学、 计算生物学和结构生物学。药理学计划采用了全面审查程序 面向博士前申请者，每年招收12-16名优秀实习生。在总共88人的注册小组中 在新来的受训人员中，90.1%符合培训条件，其中24.3%来自乌里姆团体。在过去5年内 几年来，新生的平均大学GPA为3.58，先前的研究经验为26.2个月。这个 GRE考试不再用作招生指标，我们已迁移到全面审查流程 候选人的选择要考虑全面的准备、动机和感知的毅力。我们2020年即将到来的 药理学项目班由15名学员组成，其中14名符合培训条件，2名来自 少数群体/多样性群体。我们为我们毕业生所担任的重要职位感到自豪，包括过去/现在 政府、学术界、制药和生物技术领域的科学领袖证明了我们培训计划的益处。

Project Summary This is a “new” T32 grant application seeking support for Training in the Pharmacological Sciences (TIPS) at the Weill Cornell Graduate School (WCGS). If awarded, that grant will extend support for a highly successful active T32 predoctoral training program with current funding slated to end on June 30, 2021. Our TIPS Program is inter- departmental and inter-institutional, comprising 33 outstanding faculty mentors, assembled from the Weill Cornell Medicine and the Memorial Sloan-Kettering Cancer Center. We provide an exceedingly rich research environment for training, including state-of-the-art instrumentation and core facilities, a generous space allocation to the TIPS Program and a continuing commitment to recruitment of the brightest and best new faculty. Our institutions have made an unprecedented commitment to growing their biomedical research programs, with >$3 billion raised from philanthropy spent on new construction and faculty development during the past 15 years. The participating faculty are a cohesive group of world-class investigators with vibrant ongoing research and solid records of training early-stage scientific leaders and scholars. We are dedicated mentors and biomedical researchers with labs that receive an annual average research support >$1.4M. Formal mentorship training is obligate for all of our faculty members, along with implicit bias training for the faculty and admissions committee. The current faculty comprise 22 Professors, 4 Assoc. Professors and 5 Asst. Professors with protocols in place for both adding and removing training faculty members. A major emphasis of the Program is to share the excitement of discovery with trainees, cultivate the student’s capacity for critical reasoning, and instill in students all necessary skills to fulfill aspirations they possess for the diverse career opportunities afforded by the training we offer. Notably, 97% of PhD graduates during the past 10 years have continued in either research or a research-related career. Our faculty mentors are highly-collaborative, yet with diverse research interests – providing trainees broad training opportunities in areas that include translational biomedicine, neuropharmacology, cancer biology, cell signaling, metabolism, chemical biology, synthetic chemistry, computational biology and structural biology. The Pharmacology Program has adopted a holistic review process for predoctoral applicants and enrolls 12-16 outstanding trainees annually. Among the total group of 88 enrolled or incoming trainees, 90.1% are training-eligible and 24.3% of these are from URiM groups. During the past 5 years, incoming students had a mean college GPA of 3.58 and 26.2 months of prior research experience. The GRE exam is no longer used as an admissions metric and we have migrated to a holistic review process for selection of candidates that considers overall preparation, motivation and perceived grit. Our 2020 incoming Pharmacology Program class is a group of 15 trainees, with 14 that are training-eligible and 2 from minority/diversity groups. We are proud of the prominent positions held by our graduates, including past/present scientific leaders in government, academia, pharma and biotech - attesting to the benefit of our training Program.