Predoctoral Training in Pharmacological Sciences

药理学博士前培训

• 批准号: 7892142
• 负责人: Steven S Gross
• 金额: $ 7.88万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7892142
• 关键词: Science; Training; pre-doctoral

DESCRIPTION (provided by applicant): This proposal requests support for predoctoral training in Pharmacological Sciences at the Weill Graduate School of Medical Sciences (WGSMC). The Training Program in Pharmacological Sciences at WGSMS is inter-departmental and inter-institutional, comprising a faculty of distinguished investigators assembled from the Weill Medical College of Cornell University and the Sloan-Kettering Institute. These institutions provide an exceedingly rich research environment, including state-of-the-art instrumentation and core facilities, generous space allocation to the Pharmacology Program and a continuing commitment to recruiting the brightest and best new faculty. The twenty-four participating faculty mentors are a cohesive group of world-class investigators with a strong record for training productive young scientists. The faculty have diverse research interests, providing broad opportunities for training in areas spanning molecular, cellular and systems pharmacology. Primary research areas include computational biology, chemical and structural biology, cell signaling, cardiovascular, antimicrobial, cancer and neuropharmacology. The Program enrolls 10-12 of the most outstanding students annually, with 8-10 typically eligible for NIH support. The incoming Class of 2005 will contain 8 students (of 10 entering; selected from a pool of 114 applicants) that are training-eligible. These recruited students received undergraduate degrees from top universities in the USA, had prior research experiences, mean undergraduate GPAs of 3.75 and mean GRE scores in the 75th percentile. Acceptance of such outstanding students is currently limited by financial resources, not the quality of the applicant pool. Moreover, in accord with NIH guidelines, other institutional training grants have, in recent years, diminished their support for predoctoral trainees, favoring instead the support of postdoctoral trainees. During the first year of predoctoral training, students will complete three laboratory rotations and an intensive curriculum of coursework designed to provide a solid foundation in the areas of science that are fundamental to the discipline of Pharmacology; these include chemical biology, molecular signal transduction, systems pharmacology/physiology, neuropharmacology and cancer pharmacology. The program additionally provides training in logic and experimental design as well as ethics in scientific research. Programs are in place to identify under-represented minority trainees and the Program has been highly successful in recruiting minority trainees. Indeed 3 of the 10 students committed to enter the Program in 2005 are minority candidates (2 are training-eligible). An emphasis of the Program is to cultivate the students' capacity for critical interpretation of scientific literature. This is achieved largely in an intensive small group setting wherein students are rigorously trained in the scientific method and to freely challenge established dogma.

描述(由申请人提供)：该提案请求支持威尔医学研究生院(WGSMC)的药理学博士前培训。WGSMS的药理学培训计划是跨部门和跨机构的，由来自康奈尔大学威尔医学院和斯隆-凯特琳研究所的杰出研究人员组成。这些机构提供了极其丰富的研究环境，包括最先进的仪器和核心设施，为药理学项目分配了慷慨的空间，并继续致力于招聘最聪明和最好的新教师。24名参与的教师导师是一个具有凝聚力的世界级研究人员小组，他们在培养多产的年轻科学家方面有着良好的记录。这些教师有不同的研究兴趣，为跨分子、细胞和系统药理学领域的培训提供了广泛的机会。主要研究领域包括计算生物学、化学和结构生物学、细胞信号、心血管、抗菌药物、癌症和神经药理学。该计划注册 每年有10-12名最优秀的学生，其中8-10名通常有资格获得NIH的资助。2005届新生将包括8名符合培训条件的学生(10名入学；从114名申请者中挑选出来)。这些被招募的学生获得了美国顶尖大学的本科学位，有过研究经验，本科平均GPA为3.75，GRE平均成绩在第75个百分位数。目前，这些优秀学生的录取受到财政资源的限制，而不是申请者的质量。此外，根据美国国立卫生研究院的指导方针，近年来，其他机构的培训赠款减少了对博士后学员的支持，转而支持博士后学员。在第一年的博士前培训中，学生将完成三次实验室轮换和密集的课程课程，旨在为药理学学科的基础科学领域提供坚实的基础；这些领域包括化学生物学、分子信号转导、系统药理学/生理学、神经药理学和癌症药理学。该计划还提供逻辑和实验设计方面的培训，以及科学研究中的伦理培训。已经制定了一些方案，以确定代表人数不足的少数族裔受训人员，该方案在招募少数族裔受训人员方面非常成功。事实上，2005年承诺参加该方案的10名学生中有3名是少数族裔候选人(2名符合培训资格)。该计划的一个重点是培养学生对科学文献进行批判性解释的能力。这在很大程度上是在密集的小组环境中实现的，在这种环境中，学生接受了严格的科学方法培训，并自由挑战既定的教条。