Promoting Research Training During Psychiatry Residency

促进精神病学住院医师培训期间的研究培训

• 批准号: 10671534
• 负责人: AUDREY TYRKA
• 金额: $ 21.34万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-06 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10671534
• 关键词: Acceleration; Address; Administrative Supplement; Advisory Committees; Area; Award; Basic Science; Behavior; Benchmarking; Big Data; Biological Psychiatry; Brain; Caliber; Clinical; Collaborations; Computerized Medical Record; Data; Data Set; Dedications; Development; Doctor of Philosophy; Education; Education Projects; Educational Curriculum; Environment; Equilibrium; Feedback; Fellowship; Fostering; Functional disorder; Funding; Genomics; Goals; Grant; Human; International; Journals; Leadership; Manuscripts; Mental disorders; Mentors; Mission; Molecular; Monitor; National Institute of Mental Health; Needs Assessment; Neurons; Neurosciences; Outcome; Physicians; Physiology; Prevention; Prevention strategy; Productivity; Psychiatric therapeutic procedure; Psychiatrist; Psychiatry; Publishing; Qualifying; Readiness; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Residencies; Science; Scientific Advances and Accomplishments; Scientific Inquiry; Scientist; Source; Talents; Time; Training; Training Programs; Training and Education; Translating; Travel; Underrepresented Minority; Universities; Work; Writing; career; career development; clinical training; complex data; curriculum development; design; didactic education; education planning; education research; experience; hands on research; improved; innovation; mobile computing; mobile sensor; multidisciplinary; neuroimaging; neurophysiology; next generation; posters; programs; recruit; research and development; response; skills; social media; success; symposium; tool; treatment strategy

Abstract This is a competitive continuation application of our Brown University R25 program “Promoting Research Training During Psychiatry Residency.” Exciting advances in basic and clinical psychiatry/neuroscience and genomics hold the promise of revealing the causes and potential new treatments for mental illnesses. However, a critical shortage of physician-scientists poses a threat to our ability to advance and translate discoveries from basic science into effective prevention and treatment approaches. The overarching goal of our Research Training Program (RTP) is to train the next generation of psychiatry residents to design and conduct rigorous, innovative and impactful research and develop successful careers as independently funded research-oriented physician-scientists in psychiatry/neuroscience. In the first five years of this program we have achieved our recruitment and training goals, and our residents have been remarkably successful with their research and early career development. Conducting innovative and rigorous research, our RTP residents have presented and published their findings widely and in top-tier journals. RTP residents have successfully competed for travel and poster awards, and their research projects have been funded by numerous national and local research funding awards. Our program combines an intensive longitudinal mentored research experience with an individualized research didactic curriculum and career development activities in a rich, multidisciplinary environment at Brown University. The cohesive program leadership team and Advisory Committee balance research and clinical training, monitor research and career development progress, and solicit feedback for program improvement. This application seeks to carry out the following aims: 1) Continue to recruit and train highly-qualified psychiatry residents to develop independent research careers, and 2) Build upon our existing successful program to further support resident research and career development with new and innovative components. Continuation of funding for this program would enable us to train 10 research- focused residents (two per year) over the next 5 years, thereby expanding the number of highly trained physician scientists in research domains central to the NIMH mission. The outstanding research training environment in psychiatry and brain science at Brown, characterized by internationally recognized, externally funded, innovative research programs and investigators, cross-disciplinary collaborations, and exceptionally well-qualified and dedicated mentors, makes our psychiatry residency an ideal environment in which to train the next generation of physician-scientists in psychiatry and neuroscience.

抽象的 这是我们布朗大学R25计划的竞争延续应用程序“促进研究 精神病学期间的培训。”基础和临床精神病学/神经科学和 基因组学有望揭示精神疾病的原因和潜在的新疗法。 但是，对身体科学家的严重短缺对我们提前和翻译的能力构成了威胁 从基础科学发现有效的预防和治疗方法。总体目标 我们的研究培训计划（RTP）是培训下一代精神病学居民设计和 进行严格，创新和有影响力的研究，并在独立资助时发展成功的职业 精神病学/神经科学方面的面向研究的身体科学家。在该计划的头五年中，我们 已经实现了我们的招聘和培训目标，我们的居民非常成功 他们的研究和早期职业发展。进行创新和严格的研究，我们的RTP居民 已经广泛提出并在顶级期刊上发表了他们的发现。 RTP居民已成功 竞争旅行和海报奖，他们的研究项目由许多国家资助 以及当地的研究资助奖。我们的计划结合了一项密集的纵向指导研究 具有个性化研究教学课程和职业发展活动的经验 布朗大学的多学科环境。凝聚力计划领导团队和咨询 委员会平衡研究和临床培训，监测研究和职业发展进步以及 征求计划改进的反馈。本申请旨在执行以下目的：1）继续 招募和培训高度合格的精神病学居民，以发展独立的研究职业，2）建造 我们现有的成功计划，以进一步支持居民的研究和职业发展 和创新组件。继续为该计划提供资金将使我们能够培训10项研究 - 在未来5年内，重点居民（每年两个），从而扩大了训练有素的数量 NIMH任务中心的研究领域的物理科学家。杰出的研究培训 布朗的精神病学和脑科学环境，以国际公认的外部为特征 资助，创新的研究计划和研究人员，跨学科合作以及异常 合格和敬业的导师，使我们的精神病学住所成为训练的理想环境 下一代精神病学和神经科学领域的身体科学家。

项目成果

A resource of induced pluripotent stem cell (iPSC) lines including clinical, genomic, and cellular data from genetically isolated families with mood and psychotic disorders.

诱导多能干细胞 (iPSC) 系的资源，包括来自患有情绪和精神障碍的基因隔离家族的临床、基因组和细胞数据。

• DOI: 10.1038/s41398-023-02641-w
• 发表时间: 2023-12-16
• 期刊: TRANSLATIONAL PSYCHIATRY
• 影响因子: 6.8
• 作者: Detera-Wadleigh, Sevilla D.;Kassem, Layla;Besancon, Emily;Lopes, Fabiana;Akula, Nirmala;Sung, Heejong;Blattner, Meghan;Sheridan, Laura;Lacbawan, Ley Nadine;Garcia, Joshua;Gordovez, Francis;Hosey, Katherine;Donner, Cassandra;Salvini, Claudio;Schulze, Thomas;Chen, David T. W.;England, Bryce;Cross, Joanna;Jiang, Xueying;Corona, Winston;Russ, Jill;Mallon, Barbara;Dutra, Amalia;Pak, Evgenia;Steiner, Joe;Malik, Nasir;de Guzman, Theresa;Horato, Natia;Mallmann, Mariana B.;Mendes, Victoria;Duck, Amanda L.;Nardi, Antonio E.;McMahon, Francis J.
• 通讯作者: McMahon, Francis J.

Corrigendum to "Childhood maltreatment, behavioral adjustment, and molecular markers of cellular aging in preschool-aged children: A cohort study" [Psychoneuroendocrinology 107 (2019) 261-269].

“学龄前儿童的童年虐待、行为调整和细胞衰老的分子标记：队列研究”的勘误表 [Psychoneuroendocrinology 107 (2019) 261-269]。

• DOI: 10.1016/j.psyneuen.2019.104466
• 发表时间: 2019
• 期刊: Psychoneuroendocrinology
• 影响因子: 3.7
• 作者: Ridout,KathrynK;Parade,StephanieH;Kao,Hung-Teh;Magnan,Stevie;Seifer,Ronald;Porton,Barbara;Price,LawrenceH;Tyrka,AudreyR
• 通讯作者: Tyrka,AudreyR

Becoming an Academic Researcher in Psychiatry: A View From the Trenches.

成为精神病学学术研究员：来自战壕的观点。

• DOI: 10.1007/s40596-016-0514-2
• 发表时间: 2017
• 期刊: Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry
• 作者: Ionescu,DawnF;McAdams,CarrieJ;O'Donovan,Aoife;Philip,NoahS
• 通讯作者: Philip,NoahS

Do bipolar disorder soft signs impact outcomes following Transcranial Magnetic Stimulation (TMS) therapy for depression?

双相情感障碍的软体征会影响经颅磁刺激 (TMS) 治疗抑郁症的结果吗？

• DOI: 10.1016/j.jad.2018.10.367
• 发表时间: 2019
• 期刊: Journal of affective disorders
• 影响因子: 6.6
• 作者: Bennett,Emily;Almeida,JorgeRC;Carpenter,LindaL
• 通讯作者: Carpenter,LindaL

Subcortical volumetric abnormalities in bipolar disorder.

• DOI: 10.1038/mp.2015.227
• 发表时间: 2016-12
• 期刊: MOLECULAR PSYCHIATRY
• 影响因子: 11
• 作者: Hibar, D. P.;Westlye, L. T.;van Erp, T. G. M.;Rasmussen, J.;Leonardo, C. D.;Faskowitz, J.;Haukvik, U. K.;Hartberg, C. B.;Doan, N. T.;Agartz, I.;Dale, A. M.;Gruber, O.;Kraemer, B.;Trost, S.;Liberg, B.;Abe, C.;Ekman, C. J.;Ingvar, M.;Landen, M.;Fears, S. C.;Freimer, N. B.;Bearden, C. E.;Sprooten, E.;Glahn, D. C.;Pearlson, G. D.;Emsell, L.;Kenney, J.;Scanlon, C.;McDonald, C.;Cannon, D. M.;Almeida, J.;Versace, A.;Caseras, X.;Lawrence, N. S.;Phillips, M. L.;Dima, D.;Delvecchio, G.;Frangou, S.;Satterthwaite, T. D.;Wolf, D.;Houenou, J.;Henry, C.;Malt, U. F.;Boen, E.;Elvsashagen, T.;Young, A. H.;Lloyd, A. J.;Goodwin, G. M.;Mackay, C. E.;Bourne, C.;Bilderbeck, A.;Abramovic, L.;Boks, M. P.;van Haren, N. E. M.;Ophoff, R. A.;Kahn, R. S.;Bauer, M.;Pfennig, A.;Alda, M.;Hajek, T.;Mwangi, B.;Soares, J. C.;Nickson, T.;Dimitrova, R.;Sussmann, J. E.;Hagenaars, S.;Whalley, H. C.;McIntosh, A. M.;Thompson, P. M.;Andreassen, O. A.
• 通讯作者: Andreassen, O. A.