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中文摘要
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项目总结 生物统计核心(BC)为所有人提供统计设计、数据管理和计算支持 胰腺癌孢子调查员。委员会将支持就以下各方面进行磋商和合作 研究设计、数据库开发和质量控制,以及数据的分析和解释。这个 参加生物统计核心的统计学家被选中是因为他们拥有广泛的专业知识和 具有临床试验、实验室实验、遗传学和基因组学研究以及流行病学方面的经验 学习。Graham Colditz博士和Esther Lu博士(原名刘静霞)在 综合癌症中心内的调查人员和统计学家。例如,冯高博士有 与Wang-Gillam博士(项目3的临床联合负责人)合作进行她的随机对照 化疗治疗胰腺癌的临床试验。他们得到了以下工作人员的支持 具备以下方面的专业知识:监控少数股东应计费用、ClinPortal、CaTIssue、RedCap和数据管理/分析 临床研究。总体而言,这些人与华盛顿大学学院 医学和西特曼癌症中心。他们的孢子合作将基于专业领域。 生物统计核心成员定期参加孢子项目的规划会议,并将 参与发展项目和职业发展项目的设计。这一核心的具体目标 目标1:为胰腺癌提供随时可用的统计专业知识和计算机咨询 孢子;2:提供生物统计/流行病学方面的专门知识,用于规划、分析和报告 实验室实验、流行病学研究和临床试验以及生物信息学核心资源的链接 根据需要进行微阵列数据和高通量基因组数据处理;3:为孢子提供咨询和支持 调查员及其数据收集员(技术人员、护士、数据管理员等)在数据表单领域 设计、数据收集、记录摘要、计算机化、数据库设计和管理以及数据 质量控制;4:提供所需的科学计算专门知识,以满足数据管理和 胰腺癌孢子调查人员的分析需求,并支持解释和介绍 数据。
英文摘要
PROJECT SUMMARY The Biostatistics Core (BC) provides the statistical design, data management, and computational support for all Pancreatic Cancer SPORE investigators. The BC will support consultation and collaboration on all aspects of study design, database development and quality control, as well as analysis and interpretation of data. The statisticians participating in the Biostatistics Core have been chosen for their broad range of expertise and experience in clinical trials, laboratory experiments, genetics and genomics research, and epidemiology studies. Dr. Graham Colditz and Dr. Esther Lu (formerly named Jingxia Liu) have extensive experience as investigators and statisticians within the comprehensive cancer center setting. For example, Dr. Feng Gao has collaborated with Dr. Wang-Gillam (Clinical Co-Leader on Project 3) on her ongoing randomized controlled clinical trials of chemotherapy for the treatment of pancreatic cancer. They are supported by staff with expertise in monitoring minority accrual, ClinPortal, CaTissue, REDCap and data management/analysis for clinical studies. Collectively, these individuals have affiliations with both the Washington University School of Medicine and the Siteman Cancer Center. Their SPORE collaborations will be based on areas of expertise. The Biostatistics Core members have participated regularly in planning meetings for SPORE projects, and will participate in design of developmental projects and career development projects. The specific aims of this core are to 1: Provide ready access to statistical expertise and computing consultation to the Pancreatic Cancer SPORE; 2: Provide biostatistical/epidemiological expertise for the planning, analysis and reporting of laboratory experiments, epidemiology studies, and clinical trials and links to the bioinformatics core resources for microarray data and high-throughput genomics data processing as needed; 3: Advise and support SPORE investigators and their data collectors (technicians, nurses, data managers, etc.) in the areas of data form design, data collection, record abstraction, computerization, database designing and management, and data quality control; 4: Provide the scientific computing expertise required to meet the data management and analytical needs of Pancreatic Cancer SPORE investigators, and support interpretation and presentation of data.
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Core C: Biostatistical and Bioinformatics Core
  • 批准号:
    10708578
  • 项目类别:
  • 资助金额:
    $22.59万
  • 财政年份:
    2023
  • 负责人:
    GRAHAM A. COLDITZ
  • 依托单位:
Admin-Core-001
  • 批准号:
    10709107
  • 项目类别:
  • 资助金额:
    $2.85万
  • 财政年份:
    2022
  • 负责人:
    GRAHAM A. COLDITZ
  • 依托单位:
Administrative Core
  • 批准号:
    10294013
  • 项目类别:
  • 资助金额:
    $21.71万
  • 财政年份:
    2021
  • 负责人:
    GRAHAM A. COLDITZ
  • 依托单位:
Comparative modeling of multiple myeloma across myeloma control continuuum: prevention, treatment, and disparity reduction
  • 批准号:
    10491296
  • 项目类别:
  • 资助金额:
    $64.38万
  • 财政年份:
    2021
  • 负责人:
    GRAHAM A. COLDITZ
  • 依托单位:
国内基金
海外基金
层出镰刀菌氮代谢调控因子AreA 介导伏马菌素 FB1 生物合成的作用机理
  • 批准号:
    2021JJ40433
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2021
  • 负责人:
    孙磊
  • 依托单位:
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
  • 批准号:
    32001603
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2020
  • 负责人:
    段真珍
  • 依托单位:
AREA国际经济模型的移植.改进和应用
  • 批准号:
    18870435
  • 项目类别:
    面上项目
  • 资助金额:
    2.0万元
  • 批准年份:
    1988
  • 负责人:
    史树中
  • 依托单位: