Clinical and Translational Science Award

临床和转化科学奖

• 批准号: 10707567
• 负责人: REZA NONE SHAKER
• 金额: $ 14.66万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-18 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10707567
• 关键词: Acceleration; Address; Affect; Age; Childhood; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Communities; Community Health; Development; Diagnostic; Ecosystem; Education; Effectiveness; Elderly; Engineering; Enrollment; Ensure; Environment; Evaluation; Evolution; Faculty; Fostering; Friends; Goals; Health; Health system; Healthcare; Industrialization; Informatics; Infrastructure; Institution; Knowledge; Lateral; Lead; Learning; Longevity; Measures; Methods; Mission; Modeling; National Center for Advancing Translational Sciences; Outcome; Patient Care; Patients; Performance; Population; Preventive measure; Process; Program Development; Research; Research Infrastructure; Research Personnel; Research Training; Science; Scientific Inquiry; Scientist; Services; Shapes; Site; Special Population; System; Textiles; Therapeutic; Training; Translation Process; Translational Research; Translations; Underrepresented Populations; United States National Institutes of Health; Vision; Wisconsin; Work; Workforce Development; accurate diagnostics; experience; improved; infrastructure development; innovation; member; mutual learning; next generation; novel; outreach; programs; success; translational scientist; translational study; underserved community

Contact PD/PI: SHAKER, REZA NONE Overall: Summary Lead: Reza Shaker MD 5 year direct: NIH/NCATS: $16,140,360 Institution: $34,670,756 Total: $50,811,116 In CTSA 3.0, we will continue our relentless pursuit to transform clinical and translational research in southeastern Wisconsin and the science of clinical and translational (CT) research. We remain focused on and committed to expansion of an engaged, knowledgeable, and high performing CT workforce, refinement of proficient and innovative infrastructure to support CT research and science and removing all impediments to the performance of research. Our long-standing mission to foster a borderless, collaborative, and synergistic research and research training environment for our multi-institutional translational workforce, our community stakeholders and health system members to advance the clinical/translational science research and improve the health of our community, our nation, and beyond continues to drive our direction. We remain committed to working within the CTSA consortium to learn from our colleagues across the nation and to contribute to the growing body of knowledge in the CT field. The tri-lateral mutually learning ecosystem formed by our workforce, the community, and the health system shapes the framework for strategically moving forward and has led to the concept developed in this application of integrated clinical and research ensembles (ICREs) in which patients, clinical investigators, translational researchers, health system representatives, community members, population ambassadors, basic scientists, clinicians and others are brought together. We will further expand our outreach into the communities we serve, reaching deeper into underserved communities, and will incorporate CT research across the life span to pediatric, geriatric and underrepresented populations. In the end, our goal is to use our hard-earned experience and extended capabilities to address the unmet health needs of our patients and our community while persevering to advance our infrastructure and workforce development programs to meet the standards of the developing field of translational science and research.

联系PD/PI：Shaker，Reza无 总体：摘要主角：Reza Shaker MD 5年直销：NIH/NCAT：$ 16,140,​​360机构：$ 34,670,756总计：$ 50,811,116 在CTSA 3.0中，我们将继续不懈地追求，以改变 威斯康星州东南部和临床和转化科学（CT）研究。我们仍然专注于 致力于扩大敬业，知识渊博且性能高的CT劳动力，改进 熟练和创新的基础设施支持CT研究和科学，并消除所有障碍 研究表现。我们长期以来促进无边界，协作和协同作用的使命 我们的多机构翻译员工队伍的研究和研究培训环境，我们的社区 利益相关者和卫生系统成员推进临床/转化科学研究并改善 我们社区，国家及以后的健康继续推动我们的方向。我们仍然致力于 在CTSA财团内工作，向全国各地的同事学习，并为 CT领域的知识越来越多。我们的三边互学习生态系统由我们 劳动力，社区和卫生系统塑造了战略前进和 在这种综合临床和研究合奏（ICRES）中提出了概念 患者，临床研究人员，转化研究人员，卫生系统代表，社区 成员，人口大使，基础科学家，临床医生和其他人聚集在一起。我们将进一步 将我们的宣传扩展到我们服务的社区，深入到服务不足的社区，并将 将整个寿命的CT研究纳入儿科，老年和代表性不足的人群。到底， 我们的目标是利用我们来之不易的经验和扩展能力来满足未满足的健康需求 我们的患者和社区在坚持不懈地推进基础设施和劳动力发展的同时 符合转化科学和研究发展领域标准的计划。

项目成果

Social disparities negatively impact neonatal follow-up clinic attendance of premature infants discharged from the neonatal intensive care unit.

• DOI: 10.1038/s41372-020-0659-4
• 发表时间: 2020-05
• 期刊: Journal of perinatology : official journal of the California Perinatal Association
• 作者: Swearingen C;Simpson P;Cabacungan E;Cohen S
• 通讯作者: Cohen S

Detection of changes of functioning over time after asthma exacerbation in children with the use of PROMIS domains.

• DOI: 10.1080/02770903.2021.1986839
• 发表时间: 2022-10
• 期刊: The Journal of asthma : official journal of the Association for the Care of Asthma

Hypertension during Weight Lifting Reduces Flow-Mediated Dilation in Nonathletes.

• DOI: 10.1249/mss.0000000000001150
• 发表时间: 2017-04
• 期刊: Medicine and science in sports and exercise
• 影响因子: 4.1
• 作者: Buchanan CE;Kadlec AO;Hoch AZ;Gutterman DD;Durand MJ
• 通讯作者: Durand MJ

Using a process improvement approach to identifying barriers to research in a CTSA hub environment.

• DOI: 10.1017/cts.2020.522
• 发表时间: 2020-08-19
• 期刊: Journal of clinical and translational science
• 影响因子: 2.6
• 作者: Grabenstetter D;Rashid R;Whittle J
• 通讯作者: Whittle J

Automated machine learning (AutoML) can predict 90-day mortality after gastrectomy for cancer.

• DOI: 10.1038/s41598-023-37396-3
• 发表时间: 2023-07-08
• 期刊: SCIENTIFIC REPORTS
• 影响因子: 4.6
• 作者: SenthilKumar, Gopika;Madhusudhana, Sharadhi;Flitcroft, Madelyn;Sheriff, Salma;Thalji, Samih;Merrill, Jennifer;Clarke, Callisia N.;Maduekwe, Ugwuji N.;Tsai, Susan;Christians, Kathleen K.;Gamblin, T. Clark;Kothari, Anai N.
• 通讯作者: Kothari, Anai N.