Clinical and Translational Science Award

临床和转化科学奖

• 批准号: 10707567
• 负责人: REZA NONE SHAKER
• 金额: $ 14.66万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-18 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10707567
• 关键词: Acceleration; Address; Affect; Age; Childhood; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Communities; Community Health; Development; Diagnostic; Ecosystem; Education; Effectiveness; Elderly; Engineering; Enrollment; Ensure; Environment; Evaluation; Evolution; Faculty; Fostering; Friends; Goals; Health; Health system; Healthcare; Industrialization; Informatics; Infrastructure; Institution; Knowledge; Lateral; Lead; Learning; Longevity; Measures; Methods; Mission; Modeling; National Center for Advancing Translational Sciences; Outcome; Patient Care; Patients; Performance; Population; Preventive measure; Process; Program Development; Research; Research Infrastructure; Research Personnel; Research Training; Science; Scientific Inquiry; Scientist; Services; Shapes; Site; Special Population; System; Textiles; Therapeutic; Training; Translation Process; Translational Research; Translations; Underrepresented Populations; United States National Institutes of Health; Vision; Wisconsin; Work; Workforce Development; accurate diagnostics; experience; improved; infrastructure development; innovation; member; mutual learning; next generation; novel; outreach; programs; success; translational scientist; translational study; underserved community

Contact PD/PI: SHAKER, REZA NONE Overall: Summary Lead: Reza Shaker MD 5 year direct: NIH/NCATS: $16,140,360 Institution: $34,670,756 Total: $50,811,116 In CTSA 3.0, we will continue our relentless pursuit to transform clinical and translational research in southeastern Wisconsin and the science of clinical and translational (CT) research. We remain focused on and committed to expansion of an engaged, knowledgeable, and high performing CT workforce, refinement of proficient and innovative infrastructure to support CT research and science and removing all impediments to the performance of research. Our long-standing mission to foster a borderless, collaborative, and synergistic research and research training environment for our multi-institutional translational workforce, our community stakeholders and health system members to advance the clinical/translational science research and improve the health of our community, our nation, and beyond continues to drive our direction. We remain committed to working within the CTSA consortium to learn from our colleagues across the nation and to contribute to the growing body of knowledge in the CT field. The tri-lateral mutually learning ecosystem formed by our workforce, the community, and the health system shapes the framework for strategically moving forward and has led to the concept developed in this application of integrated clinical and research ensembles (ICREs) in which patients, clinical investigators, translational researchers, health system representatives, community members, population ambassadors, basic scientists, clinicians and others are brought together. We will further expand our outreach into the communities we serve, reaching deeper into underserved communities, and will incorporate CT research across the life span to pediatric, geriatric and underrepresented populations. In the end, our goal is to use our hard-earned experience and extended capabilities to address the unmet health needs of our patients and our community while persevering to advance our infrastructure and workforce development programs to meet the standards of the developing field of translational science and research.

联系PD/PI：振荡器，REZA NONE 总体：总结负责人：Reza Shaker MD 5年直接：NIH/NCATS：16，140，360美元机构：34，670，756美元总计：50，811，116美元 在CTSA 3.0中，我们将继续不懈地追求改变临床和转化研究， 东南部威斯康星州和临床和转化（CT）研究的科学。我们仍然专注于和 致力于扩大敬业、知识渊博和高绩效的CT员工队伍，完善 熟练和创新的基础设施，以支持CT研究和科学，并消除所有障碍， 研究的表现。我们的长期使命是促进无国界、协作和协同的 研究和研究培训环境，为我们的多机构翻译工作人员，我们的社区 利益相关者和卫生系统成员，以推进临床/转化科学研究，并提高 我们的社区、我们的国家和更远的地方的健康继续推动我们的方向。我们仍然致力于 在CTSA联盟内工作，向全国各地的同事学习，并为 不断增长的CT领域知识。我们形成的三边互学生态系统， 劳动力、社区和卫生系统塑造了战略性前进的框架， 导致了在这种应用中开发的综合临床和研究集成（ICRE）的概念， 患者、临床研究者、转化研究人员、卫生系统代表、社区 成员、人口大使、基础科学家、临床医生和其他人聚集在一起。我们将进一步 将我们的服务范围扩大到我们所服务的社区，深入到服务不足的社区，并将 将整个生命周期的CT研究纳入儿科，老年人和代表性不足的人群。最后， 我们的目标是利用我们来之不易的经验和扩展的能力来解决未满足的卫生需求， 我们的病人和我们的社区，同时坚持不懈地推进我们的基础设施和劳动力发展 计划，以满足转化科学和研究的发展领域的标准。

项目成果

An EMR-Based Approach to Determine Frequency, Prescribing Pattern, and Characteristics of Patients Receiving Drugs with Pharmacogenomic Guidelines.

• DOI: 10.3390/pharmacy11060178
• 发表时间: 2023-11-17
• 期刊: Pharmacy (Basel, Switzerland)
• 作者: MacKinnon GE 3rd;Mills M;Stoddard A;Urrutia RA;Broeckel U
• 通讯作者: Broeckel U

A flow cytometric assay to detect platelet-activating antibodies in VITT after ChAdOx1 nCov-19 vaccination.

• DOI: 10.1182/blood.2021012064
• 发表时间: 2021-07-01
• 期刊: Blood
• 影响因子: 20.3
• 作者: Handtke S;Wolff M;Zaninetti C;Wesche J;Schönborn L;Aurich K;Ulm L;Hübner NO;Becker K;Thiele T;Greinacher A
• 通讯作者: Greinacher A

Extracellular vesicle-associated cytokines in sport-related concussion.

• DOI: 10.1016/j.bbi.2021.11.015
• 发表时间: 2022-03
• 期刊: Brain, behavior, and immunity
• 作者: Meier TB;Guedes VA;Smith EG;Sass D;Mithani S;Vorn R;Savitz J;Teague TK;McCrea MA;Gill JM
• 通讯作者: Gill JM

Age-Group Differences and Annual Variation in Return-To-Play Practices After Sport-Related Concussion.

• DOI: 10.1097/jsm.0000000000000871
• 发表时间: 2022-01-01
• 期刊: Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
• 作者: Kerschner AE;Huber DL;Brett BL;Meier TB;Nelson LD;McCrea MA
• 通讯作者: McCrea MA

Sex-related disparities in vehicle crash injury and hemodynamics.

车辆碰撞伤害和血流动力学方面与性别相关的差异。

• DOI: 10.3389/fpubh.2024.1331313
• 发表时间: 2024
• 期刊: Frontiers in public health
• 影响因子: 5.2
• 作者: Cronn,Susan;Somasundaram,Karthik;Driesslein,Klaus;Tomas,CarissaW;Pintar,Frank
• 通讯作者: Pintar,Frank