Translational Global Infectious Diseases Research Center

转化全球传染病研究中心

• 批准号: 10706797
• 负责人: Beth Diane Kirkpatrick
• 金额: $ 228.75万
• 依托单位: UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-15 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10706797
• 关键词: Advisory Committees; Applications Grants; Area; Award; COVID-19 pandemic; Centers of Research Excellence; Clinical; Collaborations; Communicable Diseases; Complement; Computer Models; Core Facility; Data Scientist; Dedications; Development; Discipline; Education; Evaluation; Faculty; Faculty Recruitment; Fostering; Funding; Goals; Grant; Growth; Human; Individual; Infectious Diseases Research; Institution; Language; Leadership; Logistics; Mathematics; Mentors; Mission; Modeling; Morbidity - disease rate; Phase; Physicians; Pilot Projects; Population; Population Research; Positioning Attribute; Prevention; Process; Program Development; Reporting; Research; Research Personnel; Research Project Grants; Research Support; Research Training; Resource-limited setting; Role; Scholars Program; Science; Scientist; Services; Structure; Training Programs; Training and Education; Universities; Update; Vermont; academic program; biobank; career; career development; data management; design; experience; faculty support; global health; improved; interest; meetings; member; mortality; multidisciplinary; next generation; novel; predictive modeling; prevent; programs; recruit; research and development; senior faculty; success; training opportunity; visiting scholar

PROJECT SUMMARY: Overall As demonstrated by the COVID-19 pandemic, infectious diseases are dynamic, constantly evolving threats that cause significant morbidity and mortality in all populations worldwide. The University of Vermont’s Translational Global Infectious Diseases Research (TGIR) Center of Biomedical Research Excellence (COBRE) began in 2018 under a Phase 1 award with aims to support and develop the research careers of the next generation of scientists and to build institutional strength in global infectious disease research. The TGIR COBRE’s overarching scientific goal is to perform impactful research to prevent and control infectious diseases of global significance, particularly in low-resource regions of the world. A unique feature of the TGIR COBRE is its commitment to bridging the culture gap between biomedical and quantitative data scientists. Phase 1 funding successfully supported seven research project leaders (RPLs), recruited four new junior faculty, and began a pilot award program that funded nine additional research projects. The Administrative Core offered comprehensive scientific, administrative, and career-development support, and new educational and academic programs, including Mentoring and Visiting Scholar Programs. The two research cores - the Human and Population Research (HPR) Core and the Mathematical and Computational Predictive Modeling (MCP) Core – provided prioritized services directly to RPLs, pilot project awardees, and junior faculty recruits in addition to educational and training opportunities. Phase 2 of the TGIR COBRE will build and consolidate this institutional growth and critical mass of faculty, including retention opportunities for ‘graduated’ RPLs. With a primary focus on developing junior faculty, and with the help of senior mentors and an improved mentoring plan, the TGIR COBRE will initially support the careers and research of four RPLs as well as new pilot award faculty. Three externally recruited faculty will complement existing areas of research strength. In addition, the TGIR COBRE will focus on RPL pipeline faculty and on broadening collaborations across campus and with other IDeA state programs. With institutional support, new initiatives in Phase 2 will position the TGIR COBRE for long term success. These initiatives include plans for multi-disciplinary grant proposals and provision of formal grant writer support. Financial and logistic support will also be provided for national scientific meetings to be held at UVM in order to broaden networking, visibility, and collaborative opportunities. A bioinformatician has been added to the MCP Core, expanded data management and biorepository services have been added to the HPR Core, and the Administrative Core now has enhanced focus on career development for physician-scientists. Evaluation of TGIR COBRE progress will be a continuous process led by the Leadership Team with the support of a dedicated Advisory Committee. We anticipate the TGIR COBRE becoming a sustainable academic research hub in global infectious diseases.

项目总结：总体 正如COVID-19大流行所表明的那样，传染病是动态的，不断演变的威胁， 在全世界所有人群中引起显著的发病率和死亡率。佛蒙特大学的翻译 全球传染病研究中心（TGIR）生物医学研究卓越中心（COBRE）始于2009年。 2018年根据第一阶段的奖励，旨在支持和发展下一代的研究事业。 科学家和建立全球传染病研究的机构力量。TGIR COBRE 总体科学目标是进行有影响力的研究，以预防和控制全球传染病。 特别是在世界低资源地区。TGIR COBRE的一个独特之处在于， 致力于弥合生物医学和定量数据科学家之间的文化差距。第1阶段供资 成功地支持了七个研究项目负责人（RPLs），招募了四名新的初级教师，并开始了一个 试点奖励计划资助了9个额外的研究项目。行政核心提供 全面的科学，行政和职业发展支持，以及新的教育和学术 项目，包括指导和访问学者项目。两个研究核心-人类和 人口研究（HPR）核心和数学和计算预测模型（MCP）核心- 直接向RPL、试点项目获奖者和初级教员提供优先服务， 教育和培训机会。 TGIR COBRE的第二阶段将建立和巩固这一机构的增长和教师的临界质量， 包括“毕业”RPL的保留机会。以发展初级教师为主要重点， 在高级指导员和改进的指导计划的帮助下，TGIR COBRE最初将支持 四个RPL的职业和研究以及新的试点奖教师。三名外部招聘的教师将 补充现有的研究力量。此外，TGIR COBRE将专注于RPL管道 教师和扩大跨校园的合作，并与其他IDEA国家计划。与机构 支持，第2阶段的新举措将使TGIR COBRE取得长期成功。这些举措 包括多学科赠款提案计划和提供正式的赠款撰写人支持。金融和 还将为将在维也纳外交学院举行的国家科学会议提供后勤支持，以扩大 网络、知名度和协作机会。MCP核心增加了一名生物信息学家， 扩展的数据管理和生物库服务已添加到HPR核心， 行政核心现在加强了对医生科学家职业发展的关注。评价 TGIR COBRE的进展将是一个持续的过程，由领导团队领导，并得到 专门的咨询委员会。我们期待TGIR COBRE成为一项可持续的学术研究 全球传染病中心。