Biology of Infectious Disease and Inflammation

描述（由申请人提供）：本提案是对新墨西哥州大学传染病和炎症（IDIP）扩大培训补助金（TG）的继续支持的请求。自成立以来的10年中，该培训计划为博士前和博士后学员提供了从事尖端，跨学科和以技术为中心的传染病（ID）研究并向各种科学家学习的机会。一个基本主题是促进使用不同实验方法研究传染病、宿主反应和生物威胁的研究人员之间的互动。跨部门和机构线，TG现在利用32个资助调查员的专业知识。培训教师在四个医学院部门，包括内科（8），细胞生物学和生理学（1），病理学（9）和分子遗传学和微生物学（7）任命;药学院（1）;化学和核工程UNM部门（1）;和Lovelace呼吸研究所（5）。教师培训师分为四个感兴趣的领域：1）在ID和免疫转化研究-将基础研究成果纳入临床研究，然后实践; 2）感染细胞生物学在细胞间水平的ID研究; 3）新兴ID的发病机制-疾病病因的致病机制和4）桥接技术-将尖端技术纳入ID研究。除了常规课程外，博士前和博士后学员还将完成IDIP特定课程生物医学科学研究生课程的（博士前）课程工作，包括特定的期刊俱乐部和正在进行的课程。尽管我们的TG的年轻，我们已经在招聘代表性不足的少数民族（URM）的程序的成员取得了实质性的成功，我们的毕业生，包括少数群体的成员，已经开始出现在机构，如肯塔基州或斯克里普斯研究所大学的教师队伍。我们相信我们的TG已经取得了巨大的发展势头，并准备以其更大的培训师队伍和更多的高质量少数民族和非少数民族学生来实现更大的影响。对我们计划的支持将带来丰厚的回报，扩大高度跨学科的年轻研究人员的队伍。

DESCRIPTION (provided by applicant): This proposal is a request for continued support of an expanded training grant (TG) in Infectious Disease and Inflammation (IDIP) at the University of New Mexico. In the 10 years since its inception, this training program provided pre- and postdoctoral trainees opportunities to engage in cutting edge, interdisciplinary and technology-centered infectious disease (ID) research and learn from a wide variety of scientists. An underlying theme has been the promotion of interactions between researchers who are using different experimental approaches to study infectious disease, host responses and biothreats. Crossing departmental and institutional lines, the TG now draws upon the expertise of thirty-two funded investigators. The training faculty have appointments in four School of Medicine departments that include Internal Medicine (8), Cell Biology and Physiology (1), Pathology (9) and Molecular Genetics and Microbiology (7); the College of Pharmacy (1); the UNM department of Chemical and Nuclear Engineering (1); and Lovelace Respiratory Research Institute (5). Faculty trainers fall into four areas of interest: 1) Translational Studies in ID and Immunity -bringing basic findings into clinical research, then to practice; 2) Cell Biology of Infection the study of ID at the intercellular level; 3) Pathogenesis of Emerging ID -pathogenic mechanisms of disease causation and 4) Bridging Technologies - the incorporation of cutting edge technologies to the study of ID. Both predoctoral and postdoctoral trainees are expected to complete IDIP-specific courses in addition to their regular (predoctoral) course work in the Biomedical Sciences Graduate Program including specific journal clubs and works in progress sessions. Despite the youth of our TG, we have enjoyed substantial success at recruiting members of under- represented minorities (URM) to the program, and our graduates, including members of minority groups, have already begun to appear among the ranks of the faculty of institutions such as the University of Kentucky or the Scripps Research Institute. We believe our TG has achieved great momentum and is poised to realize even greater impact with its far larger cadre of trainers and greater access to high-quality minority and non-minority students. Support for our program will yield substantial rewards, expanding the ranks of highly interdisciplinary young investigators.