Analysis Core

摘要 分析核心(ANC)将为SD AD-RCMAR的新成员和校友提供智力和技术支持 科学家。非国大将在技能、知识、测量工具和数据方面提供广泛的培训 促进其研究生产力所需的资源(即科学演示文稿、手稿出版物、 和拨款申请)，这是成为有能力竞争的独立职业科学家的要求 成功获得外部资金以进一步推进阿尔茨海默病和相关痴呆的研究 (ADRD)。除了为收集新的定量和定量数据提供培训和支持之外 定性研究侧重于通过针对多水平因素的新研究来解决ADRD不平等问题 向关注拉美裔/拉丁裔、英语水平有限(LEP)的成年人和难民提供信息 非国大将a)促进对社区的访问，确保了解，并在分析方面提供协助 新的、多样的、二次数据源，可以为学者提供一种高效、快速的手段 提高他们的研究效率和科学影响力，并以低成本测试新的创新假设；b) 为AD-RCMAR科学家提供社会流行病学方法和工具方面的强大背景，并 可以与来自大量队列研究的数据合并的背景和环境指标 监测数据集，以了解ADRD不平等的驱动因素和减少不平等的机会；以及 C)支持实施符合文化需要的健康行为的客观衡量标准 心理测量学有效工具，以及前沿、文化知识和科学有效的方法 不同人群的定性研究。这些资源将用于支持科学家在 进行研究以阐明多水平因素的作用，这些因素可以被修改以预防ADRD和 促进不同人群的健康认知老化。 非国大还将与其他SD AD-RCMAR核心合作，支持AD-RCMAR科学家在 完成他们的研究、教育和职业目标，以确保他们继续朝着 成为独立调查人员，并与协调中心一起创建、识别、编目和 传播有关新的方法学发展、测量方法或 SD AD-RCMAR产生的新数据资源。

ABSTRACT The Analysis Core (AnC) will provide intellectual and technical support for new and alumni SD AD-RCMAR Scientists. The AnC will provide extensive training in the skills, knowledge, measurement tools and data resources needed to facilitate their research productivity (i.e., scientific presentations, manuscript publications, and grant submissions), a requirement for becoming independent career scientists who can compete successfully for external funding to further advance research in Alzheimer’s Disease and Related Dementias (ADRD). In addition to providing training and support for the collection of primary data for new quantitative and qualitative studies focused on addressing ADRD inequities through novel research targeting multilevel factors to inform interventions focused on Hispanics/Latinos, limited English proficient (LEP) adults, and refugee communities, the AnC will a) facilitate access to, ensure understanding of, and provide assistance in analyzing new and diverse, secondary data sources, which can provide an efficient and rapid means for scholars to increase their research productivity and scientific impact, and test new innovative hypotheses at low cost; b) provide the AD-RCMAR Scientists with a strong background in social epidemiology methods and tools and contextual and environmental metrics that can be merged with data from numerous cohort studies and surveillance datasets to understand the drivers of inequalities in ADRD and opportunities to reduce them; and c) provide support in the implementation of objective measures of health behaviors, culturally appropriate and psychometrically valid tools, and cutting-edge, culturally-informed, and scientifically-valid approaches for qualitative studies across diverse populations. These resources will be used to support the Scientists in conducting research to illuminate the role of multi-level factors that may be modified to prevent ADRD and enhance healthy cognitive aging in diverse populations. The AnC will also work together with other SD AD-RCMAR Cores to support the AD-RCMAR Scientists in the completion of their research, education, and career goals to ensure their continued trajectories towards becoming independent investigators, and with the Coordinating Center to create, identify, catalog, and disseminate scientific information regarding novel methodological developments, measurement approaches, or new data resources produced by the SD AD-RCMAR.