Neural control of behavioural state and cognition - Role of nucleus incertus and relaxin-3

行为状态和认知的神经控制 - 不定核和松弛素 3 的作用

• 批准号: nhmrc : 1067522
• 负责人: Prof Andrew Gundlach
• 金额: $ 40.06万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/neural-control-behavioural-relaxin-3/455312
• 关键词: Neural; control; behavioural; state; cognition

Dementia and mental illness are significant social and economic burdens worldwide and knowledge of underlying causes and more effective therapies are required. Our research is using preclinical models to characterize a little studied neural network in the control of arousal states, rhythmic brain activity, and learning and memory. Our findings could advance the development of improved treatments for cognitive deficits in degenerative, age-related and psychiatric disorders.

痴呆症和精神疾病是世界范围内的重大社会和经济负担，需要了解其根本原因和更有效的治疗方法。我们的研究是使用临床前模型来描述一个很少研究的神经网络在控制唤醒状态，有节奏的大脑活动，学习和记忆。我们的研究结果可以促进退行性、年龄相关和精神疾病中认知缺陷的改进治疗方法的发展。