Relaxin-3/RXFP3 signalling and regulation of affective behaviour _ studies in normal/transgenic mice

Relaxin-3/RXFP3 信号传导和情感行为调节_正常/转基因小鼠研究

• 批准号: nhmrc : 1024885
• 负责人: Prof Andrew Gundlach
• 金额: $ 38.56万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/relaxin-3rxfp3-signalling-normaltransgenic-mice/110384
• 关键词: Relaxin; RXFP3; signalling; regulation; affective

Mental illness is a significant social and economic burden worldwide and knowledge of the underlying causes and more effective therapies are required. Our research aims to use pre-clinical animal models to characterize a little studied brain neuronal network implicated in control of arousal and stress, which could lead to improved treatment of psychiatric disorders such as depression.

精神疾病是全世界的一个重大社会和经济负担，需要了解其根本原因和更有效的治疗方法。我们的研究旨在使用临床前动物模型来表征一个很少研究的涉及控制唤醒和压力的大脑神经元网络，这可能会导致改善对抑郁症等精神疾病的治疗。