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Molecular & Developmental Biology in Pediatric Research

分子

基本信息

批准号：
7534059
负责人：
FREDERICK J SUCHY
金额：
$ 41.04万
依托单位：
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-04-15 至 2010-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7534059
关键词：
Animals Area Arts Award Basic Science Biochemistry Biomedical Research Biophysics Cells Child Child health care Childhood Clinical Credentialing Development Developmental Biology Disease Educational workshop Faculty Fetus Funding Gene Expression Profiling Genes Goals Human Genetics Image Immunobiology Individual Institution Internal Medicine K-Series Research Career Programs Knockout Mice Laboratories Mentors Methodology Molecular NCI Scholars Program Nature Pediatric Research Pediatrics Pharmacology Physiology Production Qualifying Recruitment Activity Research Research Personnel Resources Scientist Screening procedure Site Training Transgenic Organisms Underrepresented Minority base career design experience flexibility interest laboratory facility medical schools mouse model multidisciplinary novel strategies pediatric department pediatrician programs

项目摘要

The Child Health Research Career Development Award (CHRCDA) Program at the Mount Sinai School of Medicine is designed to provide mentored, intensive basic research experience for a period of 2-3 years necessary to prepare pediatricians for productive and independent careers in biomedical research and academic pediatrics. The theme of this proposal, "Molecular and Developmental Biology in Pediatrics," has unique relevance to the most common disorders seen in childhood. It encompasses normal developmental biology as well as adaptation of the fetus and child to insults occurring during ontogenesis. The multidisciplinary nature of the program - drawing from the experience of established scientists inthe Department of Pediatrics, Human Genetics, Internal Medicine, Molecular, Cellular and Developmental Biology, Immunobiology, Pharmacology and Biological Chemistry, and Physiology and Biophysics - has evolved from common interests, frequent interactions, past training of pediatric scientists, and several areas of ongoing collaborative research of the faculty. The program will provide rigorous and flexible basic research experience for young pediatric scientists through collegia! interaction with Center faculty, through startup funding as provided by new project development awards, and through the program's educational core. The selection of new project development scholars by the Program Executive Committee will be highly competitive and only those individuals with exceptional credentials or potential will be accepted by the program's Executive Committee. A novel strategy to recruit under-represented minorities to the program will be implemented. A career plan will be prepared for each scholar that will consider specific long and short- term research career goals and the competencies that will contribute to development as an independent investigator. The laboratories of the program's faculty in the Department of Pediatrics and in basic science departments will serve as sites for pediatric research faculty development. The CHRCDA program will utilize the Shared Core Laboratories at Mount Sinai School of Medicine such as state of the art methodology for cell and whole animal imaging, for production of transgenic and knockout mouse models, and for high- throughput gene screening and gene expression profiling. All CHRCDA scholars will participate in didactic sessions designed to enhance their mentored program. Regular research seminars and periodic laboratory workshops will also promote interactions among young investigators and program faculty. Overall, the program is enhanced by centralization of laboratory facilities and faculty, the existing interactions amongst research programs within the institution, the many core laboratory resources which are readily available to researchers, and the recruitment base of highly qualified applicants already attracted to the excellence of Mount Sinai's clinical departments and basic sciences.

西奈山学校儿童健康研究职业发展奖（CHRCDA）项目