Neural plasticity following lesions of the central nervous system in Multiple Sclerosis

多发性硬化症中枢神经系统损伤后的神经可塑性

• 批准号: nhmrc : 512316
• 负责人: Dr Karl Ng
• 金额: $ 34.91万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/neural-plasticity-following-multiple-sclerosis/101000
• 关键词: Neural; plasticity; following; lesions; central

The brain and nervous system can adapt to injury and disease. The compensatory changes underlying this plasticity can ameliorate disability. This project will investigate the underlying mechanisms in patients with multiple sclerosis, by examining changes in the properties of nerve fibres in the peripheral nerve. The rationale for the project is that the properties of peripheral nerve fibres can reflect, at least in part, the properties of their cell bodies within the spinal cord.

大脑和神经系统可以适应损伤和疾病。这种可塑性背后的代偿性变化可以改善残疾。该项目将通过检查周围神经中神经纤维特性的变化来研究多发性硬化症患者的潜在机制。该项目的基本原理是，周围神经纤维的特性可以反映，至少部分地，脊髓内细胞体的特性。