Developmental Projects

新英格兰地区卓越中心将利用发展项目计划来促进 在可能产生发现的领域进行创新的尖端研究，这些发现将转化为 新的疫苗、疗法和/或诊断方法，以对抗新出现的NIAID优先病原体和病原体 传染病。发展项目资源将投资于与 最有潜力发展为完整的NERCE研究计划或具有竞争力的项目 传统的美国国立卫生研究院资助。考虑到支持期限相对较短(一到两年)和相对 小投资，开发性项目的风险将更大，需要的初步数据比 传统的“RO1”式赠款。开发项目资金也将用于帮助建立新的 英格兰调查人员将项目开发到可以利用NERCE核心的阶段 设施。这笔资金将用于吸引非生物防御领域的调查人员 启动重点病原体研究项目，吸引来自机构和公司的研究人员 没有参加NERCE的人。最后，发展项目计划将用于鼓励 研究人员之间的合作，特别是基础和临床研究实验室之间的合作 传统微生物学实验室和其他基础科学学科的研究人员之间的合作(例如 免疫学家、细胞生物学家、化学生物学家、生物信息学家)。为了创造出最肥沃的 发展基金将用于对以下项目进行战略投资 高风险但潜在的高回报优先于更有可能吸引到的传统小额赠款 传统的美国国立卫生研究院资助。

The New England Regional Center of Excellence will use the Developmental Projects program to promote innovative, cutting edge research in areas that may yield discoveries that would translate into the creation of new vaccines, therapeutics and/or diagnostics to combat NIAID priority pathogens and agents of emerging infectious disease. The Developmental Projects resources will be invested in research projects with the greatest potential to grow to full NERCE research programs or to projects that would be competitive for traditional NIH funding. Given the relatively short duration of support (one or two years) and the relatively small investment, the Developmental Projects will be more risky and require less preliminary data than conventional "RO1"-like grants. Developmental Project funds will also be used to help established New England investigators develop projects to the stage where they can take advantage of the NERCE core facilities. The fund will be used to attract investigators who are not working in the area of biodefense to begin research programs on priority pathogens and to attract investigators from institutions and companies that are not participating in NERCE. Finally, the Developmental Projects program will be used to encourage collaborations among investigators, particularly between basic and clinical research laboratories and between traditional microbiology laboratories and investigators in other basic science disciplines (e.g. immunologists, cell biologists, chemical biologists, bioinformaticists). In order to create the most fertile environment for discovery, developmental funds will be used to make strategic investments in projects of high risk but potentially high return preferentially over conventional small grants that are more likely to attract traditional NIH funding.