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中文摘要
翻译
在此期间,NCGC一直致力于设计和优化一种高通量的检测方法,以实现狂犬病抑制剂的初步筛选。
英文摘要
During this period, the NCGC has worked to design and optimize a high-throughput amenable assay to enable primary screening of Rabies inhibitors. As a center, the NCGC has fostered and maintained over 130 active collaborations with both NIH and extramural investigators, facilitating drug discovery efforts across the entire spectrum of human disease. These efforts have led to dozens of high-throughput screens and a number of medicinal chemistry campaigns to further improve on screening hits, providing our collaborators and the general research community with publications and a variety of promising small molecule probes and leads. In addition, the NCGC has worked to advance a number of informatic initiatives to make better use of existing drug and disease target information and provide the general public with easily accessible resources, further catalyzing the development of new therapies for human disease.
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PRKACA for Fibrolamellar hepatocellular carcinoma
MST/ITC studies on Vimentin DHA interaction
Disrupting Type IV secretion function to prevent virulence in the pathogenic bacterium Legionella pneumophila
High-throughput multiparametric drug screening method for 3D spheroids
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Journal of Integrative Plant Biology
  • 批准号:
    31024801
  • 项目类别:
    专项基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2010
  • 负责人:
    贺萍
  • 依托单位: