Dermatoscopy in the Management of Xeroderma Pigmentosum

在与博士合作。Kenneth Kraemer和John Digiovanna，我们获得了几例色素性干皮病患者的活组织检查色素性皮肤病变的数字皮肤镜图像。这些患者在美国国立卫生研究院临床中心的主持下，Kraemer博士的临床协议集中在色素性干皮病。目前，正在使用标准的皮镜标准，对从这些患者那里获得信息的20多个病变进行分析，以确定它们在临床上是否可以被分类为恶性或良性。此外，对着色性干皮病患者的家庭成员所选择的色素病变的皮镜评估有时也会进行。该技术也被用于评估有限数量的毛硫营养不良患者。

In collaboration with Drs. Kenneth Kraemer and John Digiovanna, we have obtained digital dermatoscopic images of biopsied pigmented skin lesions on several patients with xeroderma pigmentosum. These patients have been seen at the NIH Clinical Center under the auspices of Dr. Kraemer's clinical protocol focused upon xeroderma pigmentosum. Currently the greater than twenty lesions whose information has been obtained from these patients are being analyzed, using standard dermatoscopic criteria, for features that may permit whether they can be classified clinically as malignant or benign. In addition, dermatoscopic evaluation of selected pigmented lesions on family members of those affected with xeroderma pigmentosum is sometimes performed. The technique has also been used to evaluate a limited number of patients with trichothiodystrophy.