Mays Cancer Center at UT Health SA

项目摘要-质谱学共享资源 质谱学共享资源(MSSR)的目的是提供梅斯癌症中心(MCC) 成员和德克萨斯大学圣安东尼奥分校(UT Health SA)的调查人员拥有全面的、州- 对蛋白质、代谢物和其他生物医学重要物质的表征和量化提供最先进的支持 分子使用质谱学。MSSR自1998年以来一直是癌症中心的共享资源， 占地1,034平方米。英国《金融时报》UT Health SA漫长(主)校区的两个实验室的空间。这个 MSSR由UT Health SA和MCC联合管理。蛋白质组学是MSSR的主要焦点， 提供广泛的服务，包括分子质量测定、蛋白质鉴定和相关 蛋白质修饰部位的量化和鉴定/定位。它的服务范围有 多年来，随着大量NIH支持的新设备的采购，业务大幅扩张 仪器设备赠款和来自UT系统的资金。共享资源还提供咨询服务 调查的各个阶段以及对MCC调查人员的培训。MSSR由Susan T. 温特劳布，博士，自1998年以来。温特劳布博士在利用质谱学方面拥有丰富的经验 创新研究并担任过多个国家领导职务，包括美国学会主席 用于质谱学。MSSR团队在使用质谱学解决问题方面拥有非凡的专业知识 与癌症相关的重要问题。在上一个供资期间，管理和社会责任委员会为31项同行审查提供了资金 MCC成员。由同行审查资助的MCC成员每年平均使用27%。

Project Summary—Mass Spectrometry Shared Resource The purpose of the Mass Spectrometry Shared Resource (MSSR) is to provide the Mays Cancer Center (MCC) members and University of Texas Health San Antonio (UT Health SA) investigators with comprehensive, state- of-the-art support for characterization and quantification of proteins, metabolites and other biomedically important molecules using mass spectrometry. The MSSR has been a Cancer Center Shared Resource since 1998 and is housed in 1,034 sq. ft. of space in two laboratories on the Long (main) campus of the UT Health SA. The MSSR is jointly managed by the UT Health SA and the MCC. Proteomics is the main focus of the MSSR, providing a wide range of services that include molecular mass determination, protein identification and relative quantification, and identification/localization of sites of protein modification. The scope of its service has expanded significantly over the years with the acquisition of new equipment supported by numerous NIH Instrumentation grants and by funds from the UT System. The Shared Resource also offers consultation at all stages of an investigation as well as training to MCC investigators. The MSSR has been directed by Susan T. Weintraub, Ph.D., since 1998. Dr. Weintraub has extensive experience in utilizing mass spectrometry for innovative research and served in several national leadership roles including President of the American Society for Mass Spectrometry. The MSSR team has exceptional expertise in the use of mass spectrometry to solve important cancer-related questions. During the last funding period, the MSSR serviced 31 peer-review funded MCC members. Its annual usage by peer-review funded MCC members averaged 27%.