Career Enhancement Program

项目摘要 DF/HCC GI孢子职业提升计划(CEP)旨在提供资源、结构和 鼓励和支持初级研究人员从事胃肠道基础研究、翻译研究和临床研究 癌症。首要目标是培养有才华的GI新研究人员的成功和生产力 癌症，促进他们对这一领域的持续兴趣和贡献，并增强GI孢子 通过接触新鲜的想法和人才来建立社区。CEP推进自主研究 通过三种并行办法促进初级教员的职业生涯：(A)提供研究支助和接触 建立了GI孢子调查员；(B)通过一对一和 以委员会为基础的指导；以及(C)获得促进使用临床组织样本的核心资源， 基因组数据、实验模型系统以及精细的统计和计算分析。在这些 在这方面，CEP特别努力吸引少数族裔和女性调查员进入该领域。在过去的时间里 在资金周期内，CEP支持了19名高素质的年轻调查人员，他们在短时间内取得了 在胃肠道癌症方面的卓越研究和事业进步；超过一半的获奖者是有才华的 妇女和代表不足的少数群体。GI孢子的成员和领导层有大量的 在初级教员的指导方面有记录；在过去10年中支持的20多名调查人员现在 在顶尖机构和癌症中心从事胃肠道癌症研究的终身教职或终身教职。 CEP遵循严格、公平和透明的过程来确定、挑选和指导最优秀的人 从基金会/协委会所有成员机构中抽调的年轻人。管治和审查委员会- 由杰出的高级导师领导，他们代表了 转化型GI癌症研究的成功计划-确保最佳候选人选择、支持和 个人和项目监督。CEP的具体目标是 1)培养和维护高效、公平和成功的制度，以发现有前途的年轻调查人员 寻求成为翻译胃肠道癌症研究的独立调查人员；2)提供资金和 其他支持性资源，同时密切监测获奖者的研究进展和方案 成功；3)促进指导环境，使CEP获奖者的职业发展成为 以及其他初级教员；以及4)培养翻译研究的下一代领导者 不同的胃肠道癌症，包括妇女和代表性不足的种族和少数族裔群体的成员。

Project Summary The DF/HCC GI SPORE Career Enhancement Program (CEP) aims to provide resources, structure, and incentives to attract and support junior investigators in basic, translational, and clinical research on GI cancers. The overarching goal is to nurture the success and productivity of talented new researchers in GI cancers, promote their sustained interest and contributions to the field, and to enhance the GI SPORE community through contact with fresh ideas and talent. The CEP advances the independent research careers of junior faculty through three parallel approaches: (a) providing research support and exposure to established GI SPORE investigators; (b) helping refine projects and career goals through one-on-one and committee-based mentoring; and (c) access to Core resources that facilitate use of clinical tissue samples, genomic data, experimental model systems, and refined statistical and computational analyses. In these endeavors, the CEP specifically strives to attract minority and female investigators to the field. Over the past funding cycle, the CEP supported 19 highly qualified young investigators who have in short order made exceptional research and career advances in GI cancers; more than half these awardees are talented women and underrepresented minorities. The members and leadership of the GI SPORE have a substantial record in mentorship of junior faculty; more than 20 investigators supported over the last 10 years are now in tenure-track or tenured faculty positions in GI cancer research at leading institutions and cancer centers. The CEP follows a rigorous, equitable, and transparent process to identify, select, and mentor the finest young individuals drawn from all DF/HCC member institutions. The Governance and Review Committee – led by outstanding senior mentors who represent the diversity of expertise and approaches required for a successful program in translational GI cancer research – ensures optimal candidate selection, support, and both individual and Program oversight. The Specific Aims of the CEP are 1) Cultivate and maintain an efficient, fair, and successful system to identify promising young investigators seeking to become independent investigators in translational GI cancer research; 2) Provide funding and other supportive resources, while closely monitoring awardees' research progress and programmatic success; 3) Promote a mentoring environment that enables the career development of CEP awardees as well as other junior faculty; and 4) Develop the next generation of leaders in translational investigation of diverse GI cancers, including women and members of under-represented racial and ethnic minority groups.