Administrative Core

行政核心：抽象 哥伦比亚大学乔治·M·奥布莱恩泌尿外科合作研究中心的总体目标是研究 尿路发育异常和宿主防御机制改变在慢性前列腺炎发病中的作用 尿路感染(UTI)及其并发症。这项工作建立在前五年资金和 汇聚了一个由临床、翻译和基础科学家组成的多学科协作团队， 在更好地了解泌尿系统功能障碍和疾病方面取得了重大进展。在这次更新中 申请，哥伦比亚大学奥布莱恩中心由三个研究项目组成，一个新的微生物基因组学 生物医学核心(MGBC)和管理(管理)核心。管理核心将成为 该中心通过为奥布莱恩的所有活动提供科学的领导和组织结构，并将 负责所有财务、行政、沟通和数据传播职能。有指导的 从内部和外部咨询委员会，执行委员会将提供多学科 科学领导实施管理计划，确保项目和MGBC 实现他们的目标。执行委员会还将维护各方之间存在的强大协同效应 O‘Brien合作研究中心，继续与多个NIDDK项目互动，并确保有效 在更广泛的泌尿外科社区中进行通信和数据共享。此外，它的一个关键功能 管理核心将是支持和管理奥布莱恩教育丰富和机会池 程序。教育充实计划包括哥伦比亚大学奥布莱恩暑期学生研究 计划，为期10周的密集实验室实习，在那里，医学和研究生，本科生和 高中生可以接触到泌尿外科研究和职业道路培训。教育内容的丰富 该计划与哥伦比亚大学面向多样性的外展和医生-科学家培训计划相结合，以 促进良性泌尿生殖系统疾病领域的研究事业。商机池计划将 通过严格的内部和NIDDK结构的流程继续选择特殊项目 专注于确定并与有前途的年轻或成熟的研究人员合作，他们的研究 适用于但不在泌尿外科领域。通过这些活动，管理核心将促进研究 哥伦比亚奥布莱恩中心和更大的奥布莱恩合作网络的使命。

ADMINISTRATIVE CORE: ABSTRACT The overall goal of the Columbia University George M. O’Brien Urology Cooperative Research Center is to study the role of abnormal urinary tract development and altered host defense mechanisms in the pathogenesis of urinary tract infections (UTIs) and their complications. This work builds on the previous five years of funding and has brought together a collaborative, multidisciplinary team of clinical, translational, and basic scientists that have taken significant strides in better understanding urologic dysfunction and disease. In this renewal application, the Columbia O’Brien Center consists of three Research Projects, a new Microbial Genomics Biomedical Core (MGBC), and an Administrative (Admin) Core. The Admin Core will be a central component of the Center by providing scientific leadership and organizational structure for all O’Brien activities, and will be responsible for all financial, administrative, communication, and data dissemination functions. With guidance from the Internal and External Advisory Committees, the Executive Committee will provide multidisciplinary scientific leadership to implement the management plan and ensure that the projects and the MGBC are achieving their aims. The Executive Committee will also safeguard the strong synergies that exist between all O’Brien Cooperative Research Centers, continue to interact with multiple NIDDK programs, and ensure effective communication and data sharing throughout the broader urology community. Additionally, a key function of the Admin Core will be to support and administer the O’Brien Educational Enrichment and Opportunity Pool Programs. The Educational Enrichment Program includes the Columbia O’Brien Summer Student Research Program, an intensive 10-week laboratory internship where medical and graduate students, undergraduates and high-school students are exposed to urologic research and career path training. The Educational Enrichment Program is coupled to Columbia’s diversity-oriented outreach and physician-scientist training programs to promote research careers in the field of benign genitourinary diseases. The Opportunity Pool Program will continue its selection of exceptional projects through a rigorous internal and NIDDK-structured process that focuses on identifying and collaborating with promising young or established investigators whose research is applicable to but outside the field of Urology. Through these activities, the Admin Core will promote the research mission of the Columbia O’Brien Center and the larger O’Brien Cooperative Network.