Clinical and Translational Science Award

临床和转化科学奖

• 批准号: 10112978
• 负责人: MARLA J KELLER
• 金额: $ 427.42万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-03-22 至 2023-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10112978
• 关键词: Advisory Committees; Aging; Appointment; Biological Assay; Biological Markers; Biomedical Research; Caring; Child Health; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Communities; Community Healthcare; Competence; Drug Design; Ecosystem; Evaluation; Faculty; Fostering; Funding; Gender; Generations; Goals; Health Care Research; Healthcare; Informatics; Infrastructure; Institutes; Integrated Health Care Systems; Investments; Knowledge; Laboratory Research; Leadership; Longevity; Mentors; Methods; Mission; Multi-Institutional Clinical Trial; New York City; Pathway interactions; Phase; Pilot Projects; Play; Positioning Attribute; Process; Research; Research Personnel; Research Support; Resource Development; Resources; Role; Safety; Scientist; Services; Special Population; Structure; Training; Training and Education; Translational Research; Work; Workforce Development; authority; biobank; biomedical informatics; career development; clinical practice; community engaged research; community engagement; implementation science; improved; innovation; next generation; novel; novel diagnostics; novel therapeutics; patient safety; population health; practice-based research network; precision medicine; programs; translational pipeline

The Einstein-Montefiore Institute for Clinical and Translational Research (ICTR) has evolved over the past two CTSA funding periods, embracing the broad spectrum of clinical and translational (C/T) biomedical research from T1 through T4. We have provided pathways for our clinicians and our integrated healthcare system to expand implementation science, population health, community-engaged research, and clinical trials while also encouraging basic scientists to innovate new therapeutics and diagnostics. This broad involvement with our community and investigators has allowed the CTSA to impact a wide range of research extending from drug design and improving clinical trials management, to training a new research workforce, and to using implementation science for community-engaged and healthcare research. Indeed, the ICTR’s mission—to advance research across the translational spectrum into clinical practice through its integrated infrastructure, innovative training, and institutional co-investment—has evolved in step with that of the National Center for Advancing Translational Sciences. In this application, we will 1) leverage CTSA resources with institutional assets that support state-of-the-art informatics to accelerate the transfer of discoveries to healthcare via an Evidence Generation Framework, and support regulatory streamlining, innovative analytics, and assist with all phases of C/T research; 2) develop the next generation of research workforce and teams, using novel education, training, mentoring, pilot study support, and career development resources that span translational domains; 3) expand collaborations and engagement, both with the CTSA network and other hubs, and the Bronx community and healthcare partners in an integrative paradigm with strategies developed in collaboration with community partners, investigators, and institutional leadership to improve population health; 4) advance life span, child health, and aging research across genders and special populations, by working with unique platforms for stakeholder-engaged research, patient safety and implementation science, the Montefiore Accountable Care Organization, and the New York City Practice-Based Research Network; and 5) innovate methods and processes that advance C/T sciences, and enhance quality, safety, and efficiency of C/T research. We will integrate the CTSA Trial Innovation Network into our ecosystem of multisite clinical trials, foster innovative methods for biomarker assays and biobanking for precision medicine, and leverage the CTSA Common Metrics Initiative to support our hub’s Evaluation and strategic management. Overall, the Einstein- Montefiore ICTR will fulfill NCATS’s tripartite mission to innovate, educate, and implement.

爱因斯坦-蒙蒂菲奥里临床和转化研究所（ICTR）在过去两年中不断发展