Einstein-Montefiore Clinical and Translational Science Award Hub

爱因斯坦-蒙蒂菲奥里临床和转化科学奖中心

• 批准号: 10622099
• 负责人: MARLA J KELLER
• 金额: $ 436.8万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-03-03 至 2030-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10622099
• 关键词: Abbreviations; Acceleration; Acute; Biomedical Research; COVID-19 pandemic; COVID-19 vaccination; Cessation of life; Clinic; Clinical; Clinical Engineering; Clinical Informatics; Clinical Research; Clinical Sciences; Clinical and Translational Science Awards; Communication; Communities; County; Data Science; Discipline of Nursing; Dissemination and Implementation; Effectiveness; Electronic Health Record; Ensure; Environment; Ethnic Origin; Evaluation; Evidence based program; Exclusion; Funding; Goals; Health; Health Benefit; Health Professional; Health system; Healthcare; Hispanic-serving Institution; Home; Informatics; Infrastructure; Institution; Laboratories; Lead; Leadership; Learning; Life Cycle Stages; Medical center; Medicine; Mentors; Methodology; Operations Research; Participant; Pathway interactions; Patients; Population Research; Prevention strategy; Process; Protocols documentation; Public Health; Race; Reduce health disparities; Research; Research Design; Research Personnel; Resource Informatics; Resources; Safety; Science; Services; Target Populations; Technology; Therapeutic; Training; Training Programs; Translation Process; Translational Research; Translations; Vision; Woman; clinical trial recruitment; college; community engagement; community partnership; coronavirus disease; data sharing; disorder prevention; ethnic minority; health care quality; health disparity; health equity; health equity promotion; health inequalities; implementation strategy; improved; inequitable distribution; innovation; large datasets; member; multidisciplinary; novel; open data; patient population; population health; premature; process improvement; programs; racial minority; skills; social health determinants; socioeconomics; study population; translational pipeline; treatment strategy; uptake; vaccine acceptance

The Harold and Muriel Block Institute for Clinical and Translational Research (ICTR) at the Albert Einstein College of Medicine and Montefiore Medical Center serves as the home of our CTSA program. The vision of the ICTR is to improve the health of the Bronx, and other communities that disproportionately and unjustly suffer from poor heath and premature death, by accelerating the translation of biomedical discoveries into effective and sustainable disease prevention and treatment strategies. Created in 2007, the ICTR has transformed clinical and translational research (CTR) throughout Einstein and Montefiore by creating a robust research environment; re- engineering CTR processes; integrating research and healthcare; and developing strong community relationships. The ICTR theme of “Building Bridges in the Bronx and Beyond” underscores the importance of bridging gaps between our researchers, health system leaders, clinicians, patients, communities, and CTSA partners to advance translational science and health equity. The specific aims of the ICTR are to: (1) Catalyze innovations that will enhance the efficiency and effectiveness of translational research. We will support and fund studies with high potential to overcome major CTR roadblocks and health inequities; create methodological and informatics translational science innovations; improve CTR operations, and enhance dissemination and implementation strategies. (2) Engage communities, patients, and other partners early and throughout the translational process. Our new Community and Stakeholder Engagement Research module will transform our learning health system into a “learning health research community”; promote active and continuous bidirectional communication with communities, patients and other partners; facilitate research to identify and mitigate social determinants of health, and enhance uptake of evidence-based programs by target populations. (3) Develop and implement state-of-the-art clinical research and informatics resources and services to improve the rigor, safety, efficiency, effectiveness, and generalizability of CTR. (4) Train, develop, and maintain a skilled, multidisciplinary, and diverse translational workforce to support and lead high quality research with new training and pathway programs to ensure members of historically excluded groups engage in CTR and become research leaders. (5) Partner with other CTSA hubs and the CTSA consortium to accelerate CTR and rapidly respond to urgent public health needs. Our aims are aligned with the new CTSA program goals and will enable the ICTR to maximally contribute to the collective efforts of the national collaborative CTSA consortium to deliver more treatments to more patients more quickly in the Bronx and beyond.

阿尔伯特·爱因斯坦（Albert Einstein）的哈罗德（Harold）和穆里尔（Muriel）临床与转化研究研究所（ICTR） 医学院和蒙特菲奥尔医学中心是我们CTSA计划的所在地。愿景 ICTR将改善布朗克斯的健康状况，以及其他不成比例和不公正地遭受的社区 通过加速生物医学发现为有效和 可持续疾病预防和治疗策略。 ICTR成立于2007年，已改变了临床和 整个爱因斯坦和蒙特菲奥尔的转化研究（CTR）通过创造强大的研究环境；关于- 工程CTR流程；整合研究和医疗保健；并发展强大的社区 关系。 ICTR主题是“在布朗克斯及以后建造桥梁”强调了的重要性 我们的研究人员，卫生系统领导者，临床医生，患者，社区和CTSA之间弥合差距 促进转化科学和健康公平的合作伙伴。 ICTR的具体目的是：（1）催化 将提高转化研究的效率和有效性的创新。我们将支持和资助 有可能克服主要CTR障碍和健康不平等的研究；创建方法论和 信息转化科学创新；改善CTR操作，并增强传播和 实施策略。 （2）与社区，患者和其他合作伙伴互动 翻译过程。我们的新社区和利益相关者参与研究模块将改变我们的 学习卫生系统成“学习卫生研究社区”；促进主动和连续的双向 与社区，患者和其他伴侣的沟通；促进研究以识别和减轻社会 健康的决定因素，并增强目标人群对基于证据的计划的吸收。 （3）发展和 实施最先进的临床研究和信息资源和服务，以改善严格，安全性， CTR的有效性，有效性和概括性。 （4）训练，发展和维护熟练的多学科， 和潜水员的转化劳动力以支持和领导高质量研究，并通过新的培训和途径 确保历史排除团体成员参与CTR并成为研究领导者的计划。 （5） 与其他CTSA枢纽和CTSA联盟合作，以加速CTR并迅速对紧急公众做出回应 健康需求。我们的目标与新的CTSA计划目标保持一致，并将使ICTR达到最大 为国家合作CTSA财团的集体努力做出贡献，以提供更多的治疗 在布朗克斯及以后，更多的患者更快。