Einstein-Montefiore Clinical and Translational Science Award Hub

爱因斯坦-蒙蒂菲奥里临床和转化科学奖中心

• 批准号: 10622099
• 负责人: MARLA J KELLER
• 金额: $ 436.8万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-03-03 至 2030-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10622099
• 关键词: Abbreviations; Acceleration; Acute; Biomedical Research; COVID-19 pandemic; COVID-19 vaccination; Cessation of life; Clinic; Clinical; Clinical Engineering; Clinical Informatics; Clinical Research; Clinical Sciences; Clinical and Translational Science Awards; Communication; Communities; County; Data Science; Discipline of Nursing; Dissemination and Implementation; Effectiveness; Electronic Health Record; Ensure; Environment; Ethnic Origin; Evaluation; Evidence based program; Exclusion; Funding; Goals; Health; Health Benefit; Health Professional; Health system; Healthcare; Hispanic-serving Institution; Home; Informatics; Infrastructure; Institution; Laboratories; Lead; Leadership; Learning; Life Cycle Stages; Medical center; Medicine; Mentors; Methodology; Operations Research; Participant; Pathway interactions; Patients; Population Research; Prevention strategy; Process; Protocols documentation; Public Health; Race; Reduce health disparities; Research; Research Design; Research Personnel; Resource Informatics; Resources; Safety; Science; Services; Target Populations; Technology; Therapeutic; Training; Training Programs; Translation Process; Translational Research; Translations; Vision; Woman; clinical trial recruitment; college; community engagement; community partnership; coronavirus disease; data sharing; disorder prevention; ethnic minority; health care quality; health disparity; health equity; health equity promotion; health inequalities; implementation strategy; improved; inequitable distribution; innovation; large datasets; member; multidisciplinary; novel; open data; patient population; population health; premature; process improvement; programs; racial minority; skills; social health determinants; socioeconomics; study population; translational pipeline; treatment strategy; uptake; vaccine acceptance

The Harold and Muriel Block Institute for Clinical and Translational Research (ICTR) at the Albert Einstein College of Medicine and Montefiore Medical Center serves as the home of our CTSA program. The vision of the ICTR is to improve the health of the Bronx, and other communities that disproportionately and unjustly suffer from poor heath and premature death, by accelerating the translation of biomedical discoveries into effective and sustainable disease prevention and treatment strategies. Created in 2007, the ICTR has transformed clinical and translational research (CTR) throughout Einstein and Montefiore by creating a robust research environment; re- engineering CTR processes; integrating research and healthcare; and developing strong community relationships. The ICTR theme of “Building Bridges in the Bronx and Beyond” underscores the importance of bridging gaps between our researchers, health system leaders, clinicians, patients, communities, and CTSA partners to advance translational science and health equity. The specific aims of the ICTR are to: (1) Catalyze innovations that will enhance the efficiency and effectiveness of translational research. We will support and fund studies with high potential to overcome major CTR roadblocks and health inequities; create methodological and informatics translational science innovations; improve CTR operations, and enhance dissemination and implementation strategies. (2) Engage communities, patients, and other partners early and throughout the translational process. Our new Community and Stakeholder Engagement Research module will transform our learning health system into a “learning health research community”; promote active and continuous bidirectional communication with communities, patients and other partners; facilitate research to identify and mitigate social determinants of health, and enhance uptake of evidence-based programs by target populations. (3) Develop and implement state-of-the-art clinical research and informatics resources and services to improve the rigor, safety, efficiency, effectiveness, and generalizability of CTR. (4) Train, develop, and maintain a skilled, multidisciplinary, and diverse translational workforce to support and lead high quality research with new training and pathway programs to ensure members of historically excluded groups engage in CTR and become research leaders. (5) Partner with other CTSA hubs and the CTSA consortium to accelerate CTR and rapidly respond to urgent public health needs. Our aims are aligned with the new CTSA program goals and will enable the ICTR to maximally contribute to the collective efforts of the national collaborative CTSA consortium to deliver more treatments to more patients more quickly in the Bronx and beyond.

阿尔伯特·爱因斯坦哈罗德和穆里尔·布洛克临床与转化研究所 (ICTR) 医学院和 Montefiore 医疗中心是我们 CTSA 项目的所在地。的愿景 卢旺达问题国际法庭旨在改善布朗克斯区以及其他遭受不成比例和不公正苦难的社区的健康 通过加速将生物医学发现转化为有效和有效的成果，避免健康状况不佳和过早死亡 可持续的疾病预防和治疗策略。卢旺达问题国际法庭成立于 2007 年，它改变了临床和 通过创建强大的研究环境，在爱因斯坦和蒙蒂菲奥里进行转化研究（CTR）；关于- 设计点击率流程；整合研究和医疗保健；并发展强大的社区 关系。卢旺达问题国际法庭的主题是“在布朗克斯及其他地区架起桥梁”，强调了 弥合我们的研究人员、卫生系统领导者、临床医生、患者、社区和 CTSA 之间的差距 合作伙伴推进转化科学和健康公平。卢旺达问题国际法庭的具体目标是： (1) 促进 将提高转化研究的效率和效果的创新。我们将支持和资助 具有克服主要点击率障碍和健康不平等的巨大潜力的研究；创建方法论和 信息学转化科学创新；改善CTR运营，加强传播和 实施策略。 (2) 在整个过程中尽早让社区、患者和其他合作伙伴参与进来 翻译过程。我们新的社区和利益相关者参与研究模块将改变我们的 学习健康系统转变为“学习健康研究社区”；促进积极、持续的双向 与社区、患者和其他合作伙伴的沟通；促进研究以识别和减轻社会影响 健康的决定因素，并加强目标人群对循证方案的采用。 (3) 开发和 实施最先进的临床研究和信息学资源和服务，以提高严谨性、安全性、 点击率的效率、有效性和普遍性。 (4) 培养、培养和维持一支熟练的、多学科的、 和多元化的翻译人员，通过新的培训和途径支持和领导高质量的研究 确保历史上被排除群体的成员参与 CTR 并成为研究领导者的计划。 (5) 与其他 CTSA 中心和 CTSA 联盟合作，加快点击率并快速响应紧急公众 健康需求。我们的目标与新的 CTSA 计划目标一致，将使卢旺达问题国际法庭能够最大限度地 为国家 CTSA 合作联盟的集体努力做出贡献，为患者提供更多治疗 在布朗克斯及其他地区更快地增加更多患者。