Hypertension and Cardiorenal Diseases Research Training Program

描述(由申请人提供)：项目摘要密西西比大学医学中心(UMMC)心血管研究历史悠久。这项研究的大部分都是在生理系进行的，他们的努力是为了开发对心血管和肾脏系统的定量和综合分析。此外，UMMC还扩大了对高血压和心肾疾病的基础和临床研究，包括药理学、生物化学、神经科学、医学、内分泌学和妇产科等多个科室和项目。UMMC也是杰克逊心脏研究的检查中心，该研究主要关注非裔美国人的心血管疾病。UMMC还参与了ALLHAT等几项重大临床试验。因此，UMMC在心血管疾病方面有各种各样的基础、临床和人群研究计划。多学科高血压和心脏肾脏疾病研究(HCDR)培训计划的主要目标是招募、培训和指导高血压和心血管和肾脏研究的博士后和博士后学生，使他们成为该领域的下一代研究人员。为了实现这一目标，密歇根大学心血管肾脏研究卓越中心(CECR)将为博士后和博士后学生提供一个激励和富有成效的指导环境。HCDR培训计划不仅利用了UMMC在心血管和肾脏研究领域的一批强大的基础科学和临床研究人员的专业知识，还利用了这些现有实验室和CECR核心设施提供的资源。这项培训拨款提案的具体目的如下：1.培训博士前学生(3)在高血压和心血管-肾脏疾病研究方面采用多学科方法进行课程工作和研究机会的培训。2.提供博士后(5)高血压和心血管肾脏病研究的多学科培训和指导3.招收和培训高血压和心血管肾脏病研究的少数博士后和博士后。资助UMMC的HCDR培训计划将提高这一多学科计划的受训人员的质量和数量，并极大地增强我们在高血压和心肾疾病研究方面培训下一代生物医学科学家的能力。

DESCRIPTION (provided by applicant): Project Summary There has been a long history of cardiovascular research at the University of Mississippi Medical Center (UMMC). Much of this research has been conducted in the Department of Physiology where their efforts are directed toward developing a quantitative and integrated analysis of the cardiovascular and renal systems. In addition both basic and clinical research on hypertension and cardio-renal diseases at UMMC have expanded in various departments and programs such as Pharmacology, Biochemistry, Neurosciences, Medicine, Endocrinology, and Obstetrics and Gynecology. UMMC also serves as the Examination Center for the Jackson Heart Study that has a major focus on cardiovascular disease in African Americans. UMMC has also been a participant is several major clinical trials such as ALLHAT. Thus, UMMC has a diversity of basic, clinical, and population research programs in cardiovascular diseases. The main objective of the multidisciplinary Hypertension and Cardiorenal Diseases Research (HCDR) Training Program is to recruit, train, and mentor pre-doctoral and postdoctoral students in hypertension and cardiovascular and renal research so that they become the next generation of researchers in this field. To achieve this goal the Center for Excellence in Cardiovascular-Renal Research (CECR) at UMMC will provide a stimulating and productive mentoring environment for pre-doctoral and postdoctoral students. The HCDR Training Program not only capitalizes on the expertise of a strong group of basic science and clinical investigators in the field of cardiovascular and renal research at UMMC but also the resources provided by these established laboratories and the CECR core facilities. The specific aims of this training grant proposal are as follows: 1. To train pre-doctoral students (3) in a multi-disciplinary approach in course work and research opportunities in hypertension and cardiovascular-renal disease research. 2. To provide postdoctoral students (5) multi-disciplinary training and mentoring in hypertension and cardiovascular-renal disease research 3. To recruit and train minority pre-doctoral and postdoctoral students in hypertension and cardiovascular- renal diseases research. Funding of the HCDR training program at UMMC would increase the quality and quantity of trainees in this multi-disciplinary program and greatly enhance our ability to train the next generation of biomedical scientists in hypertension and cardio-renal diseases research.