Building Heart, Lung, Blood and Sleep Diseases and Disorders Late-Stage Translation Phase 4 Research Capacity in Malawi

在马拉维建设心、肺、血液和睡眠疾病和紊乱的后期转化第 4 阶段研究能力

• 批准号: 9969197
• 负责人: MINA CHRISTINE HOSSEINIPOUR
• 金额: $ 13.86万
• 依托单位: UNIVERSITY OF MALAWI
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2022-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9969197
• 关键词: Africa; African; Area; Award; Chest; Clinical; Clinical Research; Country; Cross-Sectional Studies; Data; Data Analyses; Databases; Disease; Ensure; Exercise; Faculty; Focus Groups; Funding; Government; Health; Heart Diseases; Hematological Disease; Infrastructure; Institution; International; Internships; Intervention; Investments; Laboratories; Lead; Lung diseases; Malawi; Medicine; Mentors; Methods; Needs Assessment; North Carolina; Operations Research; Phase; Prevalence; Prevention; Program Development; Research; Research Infrastructure; Research Training; Resources; Review Literature; Risk Factors; Scientist; Site; Sleep Disorders; Societies; Surveys; Telephone Interviews; Training; Training Programs; Translations; Trust; United States National Institutes of Health; Universities; Update; Visit; Vital Status; Work; burden of illness; college; cost; design; disorder risk; epidemiology study; experience; graduate student; implementation research; implementation science; medical schools; programs; skill acquisition; skills

Building Heart, Lung, Blood and Sleep Diseases and Disorders Late-Stage Translation Phase 4 Research Capacity in Malawi Project Summary Non-communicable diseases (NCDs), including heart, lung, blood and sleeping diseases and disorders (HLBS) are increasing in prevalence globally. In Africa, it is crucial to have a clear understanding of the burden and risk factors for these conditions in order to design context specific interventions. In Malawi, despite the growing burden of HLBS, there is a shortage of locally relevant research evidence and a critical mass of scientists. The proposed program will build sustainable HLBS-focused late-stage translation phase 4 research (T4TR) capacity in Malawi and will utilize this capacity to do in-depth research of infrastructure and diseases burden needs assessments to design a context specific HLBS T4TR research plan. The application brings together a consortium of key institutions already involved in HLBS training and research in Malawi. The consortium is purposefully designed to build capacity within the University of Malawi-College of Medicine (COM), the only public medical school in the country, and the Malawi Ministry of Health (MoH), to ensure sustainability. This application focuses on four overarching aims: 1. Skills development activities to build HLBS T4TR capacity within COM's faculty, graduate students, and postgraduate clinical trainees and frontline health workers from MoH and implementation partners. This skills development will leverage two of the consortium's ongoing research training programs (the COM-University of North Carolina's ongoing implementation science training program (NIH D43 TW010060-01: M-HIRST) and the Pan African Thoracic Society, Methods in Epidemiologic, Clinical and Operations Research (PATS-MECOR) program led by the Malawi-Liverpool Wellcome Trust Clinical Research Programme (MLW). This skills development program will be supplemented by a mentored research awards and an internship program housed at partners' implementation sites. 2. We will conduct an in-depth national HLBS T4 research infrastructure needs assessment using short written surveys, facility visits and audits, nominal focus group discussions and telephone interviews. 3. A disease burden assessment will be conducted using existing data on disease prevalence surveys supplemented by cross- sectional surveys and thorough literature reviews. 4. Finally, we will utilize the skills development activities together with the findings of the needs assessments to create a comprehensive, actionable, and Malawi specific T4TR research plan for priority HLBS. We will utilize local, national, regional and international dissemination avenues to disseminate program experiences and findings.

建筑心肺、血液和睡眠疾病及障碍晚期翻译 马拉维的第四阶段研究能力 项目摘要 非传染性疾病，包括心肺、血液和睡眠疾病以及 疾病(HLBS)在全球范围内的流行率正在上升。在非洲，关键是要有一个明确的 了解这些情况的负担和风险因素，以便设计环境 具体的干预措施。在马拉维，尽管HLBS的负担越来越重，但仍缺乏 与当地相关的研究证据和足够多的科学家。拟议的计划将 建立可持续的以HLBS为重点的后期翻译阶段4研究(T4TR)能力 马拉维将利用这一能力对基础设施和疾病进行深入研究 负担需求评估，以设计特定背景的HLBS T4TR研究计划。这个 申请将已经参与HLBS培训的关键机构联盟聚集在一起 并在马拉维进行研究。该财团的目的是在 马拉维大学医学院(COM)是马拉维唯一的公立医学院， 和马拉维卫生部(MoH)，以确保可持续性。 此应用程序侧重于四个总体目标：1.要建立的技能发展活动 COM的教职员工、研究生和临床研究生的HLBS T4TR能力 来自卫生部和实施伙伴的受训人员和一线卫生工作者。这项技能 开发将利用该联盟正在进行的两个研究培训计划( COM-北卡罗来纳大学正在进行的实施科学培训计划(NIH D43 TW010060-01：M-Hirst)和泛非胸科学会，流行病学方法， 马拉维-利物浦牵头的临床和业务研究(PATS-MECOR)计划 惠康信托临床研究计划(MLW)。这项技能发展计划将是 辅以指导研究奖和合作伙伴的实习计划 实施地点。2.我们将深入开展全国HLBS T4研究 使用简短的书面调查、设施访问和审计进行基础设施需求评估， 名义上的焦点小组讨论和电话采访。3.疾病负担评估 将利用现有的疾病流行调查数据进行，并辅之以交叉- 横断面调查和全面的文献综述。4.最后，我们将利用这些技能 发展活动以及需求评估的结果，以创建一个 针对优先HLBS的全面、可操作和马拉维特有的T4TR研究计划。 我们将利用地方、国家、区域和国际传播渠道传播 计划经验和调查结果。

项目成果

Task-shifting to improve asthma education for Malawian children: a qualitative analysis.

• DOI: 10.1186/s12960-021-00576-1
• 发表时间: 2021-03-02
• 期刊: Human resources for health
• 影响因子: 4.5
• 作者: Nkhalamba L;Rylance S;Muula AS;Mortimer K;Limbani F
• 通讯作者: Limbani F

Quality of life among type 2 diabetes mellitus patients at Kamuzu Central Hospital in Lilongwe, Malawi: A mixed-methods study.

• DOI: 10.1371/journal.pgph.0002367
• 发表时间: 2023
• 期刊: PLOS global public health

Decentralized Heart Failure Management in Neno, Malawi.

• DOI: 10.5334/gh.1210
• 发表时间: 2023
• 期刊: Global heart
• 影响因子: 3.7
• 作者: Mailosi BGD;Ruderman T;Klassen SL;Kachimanga C;Aron MB;Boti M;Kumwenda K;Bukhman G;Muula AS;Banda NPK;Kwan GF
• 通讯作者: Kwan GF

Uptake of diabetic retinopathy screening at a secondary level facility in Malawi.

在马拉维的二级设施中摄取糖尿病性视网膜病变筛查。

• DOI: 10.1371/journal.pgph.0002567
• 发表时间: 2023
• 期刊: PLOS global public health

The WHO-TDR Dissemination and Implementation Massive Open Online Course (MOOC): Evaluation and Lessons Learned from Eight Low-and Middle-Income Countries.

WHO-TDR 传播和实施大规模开放在线课程 (MOOC)：八个低收入和中等收入国家的评估和经验教训。

• DOI: 10.21203/rs.3.rs-1455034/v1
• 发表时间: 2022
• 期刊: Research square
• 作者: Rakhra,Ashlin;Hooley,Cole;Fort,Meredith;Weber,MaryBeth;Price,LeShawndra;Nguyen,HoaL;Ramirez,Manuel;Muula,AdamsonS;Hosseinipour,Mina;Apusiga,Kingsley;Davila-Roman,Victor;Gyamfi,Joyce;Adjei,KeziaGladysAmaning;Andesia,Josephin
• 通讯作者: Andesia,Josephin