Vision disorders in adolescents following concussion

7.项目总结 在美国，每年大约有360万例脑震荡。受影响最大的 年龄在11岁到18岁之间，该年龄段的脑震荡诊断率正在上升。 儿童和青少年特别容易受到脑震荡的有害影响，因为 他们的更高水平的认知功能仍在发展中。尽管许多青少年完全康复了 从四周内的脑震荡开始，相当数量的青少年有较长的脑震荡 复苏可能会持续数周甚至数月。康复期间报告的常见症状 脑震荡导致注意力难以集中，视力模糊和/或复视，在以下情况下失去位置 阅读，还有头痛。据报道，至少有一种视力障碍出现在40%-70%的 患有脑震荡的青少年。恢复期持续的视力障碍有 与认知功能下降有关，并可能与长期脑震荡有关 恢复。尽管有报道称患有脑震荡和糖尿病的青少年视力障碍的频率 脑震荡和视力障碍的非视觉症状有明显重叠，目前仍不清楚 视力障碍在康复过程中可能起到什么作用及其长期影响。穿过 我们将实现两个具体目标：1)论证高参与率和保留率的可行性 脑震荡青少年和同期组的10天、1个月和3个月的随访 对非脑震荡青少年进行比较；2)优化我们的视力测试单元 并为我们关于视觉的自然历史研究开发了一本全面的程序手册 脑震荡青少年的精神障碍。我们的长期目标是进行未来的多中心， 多学科自然史研究，向医疗保健社区通报视力障碍 以及它们在整个康复过程中与认知能力的联系。

7. Project Summary Approximately 3.6 million concussions occur every year in the United States. The largest affected group is 11- to 18-year-olds, and the diagnosis of concussion in that age group is increasing. Children and adolescents are particularly vulnerable to the harmful effects of concussion because their higher-level cognitive functions are still developing. Although many adolescents fully recover from their concussion within four weeks, a significant number of adolescents have a prolonged recovery that may last weeks or even months. Common symptoms reported during the recovery from concussion are difficulty concentrating, blurred and/or double vision, losing one’s place when reading, and headaches. At least one vision disorder is reported to be present in 40-70% of adolescents with concussion. Persistent vision disorders during the recovery period are associated with decreased cognitive function and may be associated with prolonged concussion recovery. Despite the reported frequency of vision disorders in adolescents with concussion and the clear overlap in non-visual symptoms for concussion and vision disorders, it is still unclear what role vision disorders may play in the recovery process and their longer-term impact. Through two specific aims we will: 1) Demonstrate feasibility of high participant accrual and retention rates at 10-day, one-month, and three-month visits in concussed adolescents and in a concurrent group of non-concussed adolescents for comparative purposes; and 2) Optimize our vision test battery and develop a comprehensive manual of procedures for our natural history study on vision disorders in adolescents with concussion. Our long-term goal is to conduct a future multi-center, multidisciplinary natural history study to inform the healthcare community about vision disorders and their association with cognitive abilities throughout the recovery process.