Vision disorders in adolescents following concussion

青少年脑震荡后视力障碍

• 批准号: 10250539
• 负责人: LISA A Jordan
• 金额: $ 26.19万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-30 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10250539
• 关键词: 18 year old; Adolescent; Affect; Area; Asthenopia; Blurred vision; Brain Concussion; Child; Childhood; Clinical; Clinical Trials; Collaborations; Communities; Cross-Sectional Studies; Data; Diagnosis; Diplopia; Disease; Eligibility Determination; Epidemiology; Evaluation; Eye Movements; Fatigue; Frequencies; Functional disorder; Funding; Future; Goals; Grant; Headache; Health Personnel; Injury; Intervention; Literature; Manuals; Medical; Memory; Natural History; Nausea; Neurology; Outcome; Participant; Physicians; Play; Primary Health Care; Procedures; Process; Protocols documentation; Provider; Reading; Recording of previous events; Recovery; Recruitment Activity; Reporting; Research; Research Design; Resolution; Retrospective Studies; Role; Saccades; Schools; Speed; Sports Medicine; Standardization; Symptoms; Testing; Time; United States; Vertigo; Vision; Vision Disorders; Vision Tests; Visit; Visual; Youth; age group; clinical center; cognitive ability; cognitive function; cognitive performance; cognitive task; common symptom; comorbidity; comparative; comparison group; concussive symptom; evidence base; healthcare community; improved; multidisciplinary; prospective; recruit; retention rate; sample fixation; standard of care; visual motor

7. Project Summary Approximately 3.6 million concussions occur every year in the United States. The largest affected group is 11- to 18-year-olds, and the diagnosis of concussion in that age group is increasing. Children and adolescents are particularly vulnerable to the harmful effects of concussion because their higher-level cognitive functions are still developing. Although many adolescents fully recover from their concussion within four weeks, a significant number of adolescents have a prolonged recovery that may last weeks or even months. Common symptoms reported during the recovery from concussion are difficulty concentrating, blurred and/or double vision, losing one’s place when reading, and headaches. At least one vision disorder is reported to be present in 40-70% of adolescents with concussion. Persistent vision disorders during the recovery period are associated with decreased cognitive function and may be associated with prolonged concussion recovery. Despite the reported frequency of vision disorders in adolescents with concussion and the clear overlap in non-visual symptoms for concussion and vision disorders, it is still unclear what role vision disorders may play in the recovery process and their longer-term impact. Through two specific aims we will: 1) Demonstrate feasibility of high participant accrual and retention rates at 10-day, one-month, and three-month visits in concussed adolescents and in a concurrent group of non-concussed adolescents for comparative purposes; and 2) Optimize our vision test battery and develop a comprehensive manual of procedures for our natural history study on vision disorders in adolescents with concussion. Our long-term goal is to conduct a future multi-center, multidisciplinary natural history study to inform the healthcare community about vision disorders and their association with cognitive abilities throughout the recovery process.

7.项目摘要 在美国，每年大约有360万例脑震荡。受影响最大的 年龄组为11至18岁，该年龄组脑震荡的诊断正在增加。 儿童和青少年特别容易受到脑震荡的有害影响， 他们的高级认知功能仍在发展。尽管许多青少年完全康复 从他们的脑震荡四周内，相当多的青少年有一个长期的 恢复可能持续数周甚至数月。恢复期间报告的常见症状 从脑震荡是难以集中，模糊和/或复视，失去一个人的地方时， 阅读和头痛。据报道，40-70%的人至少存在一种视力障碍。 青少年脑震荡恢复期的持续性视力障碍是 与认知功能下降有关，并可能与长期脑震荡有关 复苏尽管有报道称，青少年脑震荡和 脑震荡和视力障碍的非视觉症状的明显重叠，目前还不清楚 视力障碍在恢复过程中可能发挥的作用及其长期影响。通过 我们将实现两个具体目标：1）证明高参与者应计率和留存率的可行性 在脑震荡青少年和同期组的10天、1个月和3个月访视中 非脑震荡青少年的比较目的;和2）优化我们的视力测试电池 并为我们的视觉自然史研究制定一份全面的程序手册 青少年脑震荡的障碍。我们的长期目标是进行未来的多中心， 多学科自然史研究，以告知医疗保健界有关视力障碍 以及它们在整个恢复过程中与认知能力的联系。