The Papuan Indigenous Model of Voluntary Medical Male Circumcision (VMMC)
巴布亚原住民自愿医疗男性包皮环切术 (VMMC) 模式
基本信息
- 批准号:10256068
- 负责人:
- 金额:$ 18.4万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-09-07 至 2023-08-31
- 项目状态:已结题
- 来源:
- 关键词:AIDS preventionAbstinenceAdolescentAdoptedAdultAffectAgeAttentionBacterial VaginosisBehaviorCitiesClinicClinical TrialsCommunitiesCommunity Health SystemsConsultationsCounselingCountryDataDevice RemovalDevicesEducationElderlyEnsureEpidemicEthnic groupEventExcisionExposure toFemaleFocus GroupsGeneral PopulationGenitalGenitaliaGovernmentGovernment ProgramsHIVHIV InfectionsHealthHealthcare SystemsHeterosexualsHuman PapillomavirusIncidenceIndigenousIndonesiaInfectionInjecting drug userInternationalInterventionInterviewIslandLifeLocationMale AdolescentsMale CircumcisionMedicalModelingMuslim population groupOperative Surgical ProceduresOutcome StudyParentsPerceptionPoliciesPopulationPrevalencePreventionPrevention strategyPreventiveProceduresProviderProvinceQuestionnairesRecommendationReligious BeliefResearchResourcesRestRiskSafe SexSafetySchoolsServicesSex BehaviorSexual HealthSexual PartnersTestingTimeTrainingUlcerVoluntary ProgramsYouthacceptability and feasibilitybaseboyscost effectivenessdesignexperiencehigh riskimplementation studymalemembermenmen who have sex with menpenis foreskinprevention serviceprimary outcomeprogramsresponsesatisfactionsecondary outcomesexual HIV transmissionsexual risk behaviorsexual risk takingsuccesstransmission processuptake
项目摘要
ABSTRACT
The number of people living with HIV continues to climb in Indonesia, especially in the province of Tanah
Papua where prevention efforts based on abstinence or safer sex have shown only modest success, and PreP
is not government approved for use. Voluntary medical male circumcision (VMMC) as a one-time procedure
has been shown through clinical trials to reduce the risk of heterosexually acquired HIV infection in men by
approximately 60%. Currently VMMC is not offered in Tanah Papua, where unlike the rest of Indonesia, the
great majority of men are uncircumcised. This research will develop, implement, and assess the feasibility,
acceptability, and safety of the Papuan Indigenous Model (PIM) of VMMC as a comprehensive, culturally and
age-appropriate HIV intervention for Papuan males ages 12-18. Circumcision offers partial life-time HIV
protection and a valuable opportunity to engage adolescent males with the health care system while instilling
HIV preventive behaviors. The study’s 4 aims: AIM 1: To engage Papuan community members to explore
acceptability, barriers and facilitators for introducing a school-based age and culturally appropriate,
comprehensive VMMC intervention to reduce HIV incidence in the Papuan population. AIM 2: To assess the
capacity of the community health system to meet international criteria for safe comprehensive VMMC services
and to ensure the availability of resources and training necessary to meet these criteria in selected clinics. AIM
3: To design the PIM of school-based adolescent VMMC based on information collected in Aims 1 and 2 and in
consultation with a community advisory board, the Ministry of Health and the Ministry of Education. AIM 4: To
pilot-test the school-based PIM Intervention of VMMC with 400 boys ages 12-18 years at two HIV high-risk
Papuan locations: the Nabire and Jayapura. Data will be collected through focus groups, in-depth interviews
with key community stakeholders and adolescents, brief questionnaires administered to adolescent males pre-
and 6 weeks post-surgery, a random subsampling of 30 boys interviewed 12 weeks post device-removal to
detect changes in levels of satisfaction, onset of sexual activity, and possible compensatory sexual risk taking.
Parent interviews will gauge their satisfaction. Primary outcomes are the proportion of adolescent males
exposed to school-based PIM VMMC educational and informational sessions who get circumcised and surgical
event safety. Secondary outcomes are satisfaction by adolescent males and parents, any sexual activity within
6 weeks after circumcision, changes in sexual risk behaviors between base-line and 12 weeks after
circumcision, and perceptions of providers regarding MC training and implementation, ease of device use, and
challenges encountered. The impact of the research lies in having developed and rigorously pilot-tested a
culturally-appropriate, and age-tailored model of VMMC services for adolescent males ages 12-18 in Papua,
where other HIV prevention services have been difficult to implement and the epidemic is proving intractable.
抽象的
印度尼西亚艾滋病毒感染者人数持续攀升,特别是在塔纳省
巴布亚,基于禁欲或安全性行为的预防工作仅取得了一定的成功,而 PreP
未经政府批准使用。自愿医疗男性包皮环切术 (VMMC) 作为一次性手术
临床试验表明,通过以下方式可降低男性异性感染艾滋病毒的风险:
大约60%。目前,丹那巴布亚不提供 VMMC,与印度尼西亚其他地区不同,该地区
绝大多数男性未受割礼。这项研究将开发、实施和评估可行性,
VMMC 的巴布亚土著模式 (PIM) 作为一个综合性、文化性和安全性的可接受性和安全性
对 12-18 岁巴布亚男性进行适合年龄的艾滋病毒干预。包皮环切术可导致部分终身感染艾滋病毒
保护和让青春期男性参与医疗保健系统的宝贵机会,同时向他们灌输
艾滋病毒预防行为。该研究的 4 个目标: 目标 1:让巴布亚社区成员参与探索
引入学龄和文化适宜性的可接受性、障碍和促进因素,
全面的 VMMC 干预措施,以减少巴布亚人口的艾滋病毒发病率。目标 2:评估
社区卫生系统满足安全综合 VMMC 服务国际标准的能力
并确保选定诊所能够获得满足这些标准所需的资源和培训。目的
3:根据目标 1 和 2 以及目标 2 中收集的信息设计校本青少年 VMMC 的 PIM
与社区咨询委员会、卫生部和教育部协商。目标 4:
对 400 名 12 至 18 岁男孩进行 VMMC 校本 PIM 干预试点测试,两名艾滋病毒高危人群
巴布亚地点:纳比雷和查亚普拉。将通过焦点小组、深度访谈收集数据
与主要社区利益相关者和青少年一起,在
手术后 6 周,在装置移除后 12 周对 30 名男孩进行了随机抽样调查,
检测满意度水平的变化、性活动的开始以及可能的补偿性性冒险。
家长访谈将衡量他们的满意度。主要结果是青春期男性的比例
接受包皮环切术和手术的人参加基于学校的 PIM VMMC 教育和信息会议
活动安全。次要结果是青少年男性和父母的满意度、任何性活动
包皮环切术后 6 周,基线与术后 12 周之间性危险行为的变化
包皮环切术以及提供者对 MC 培训和实施、设备使用便利性的看法,以及
遇到的挑战。该研究的影响在于开发并经过严格的试点测试
为巴布亚 12-18 岁的男性青少年提供适合文化和年龄的 VMMC 服务模式,
其他艾滋病毒预防服务难以实施,而且该流行病也很棘手。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Robert Converse Bailey其他文献
Robert Converse Bailey的其他文献
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{{ truncateString('Robert Converse Bailey', 18)}}的其他基金
The Papuan Indigenous Model of Voluntary Medical Male Circumcision (VMMC)
巴布亚原住民自愿医疗男性包皮环切术 (VMMC) 模式
- 批准号:
10079975 - 财政年份:2020
- 资助金额:
$ 18.4万 - 项目类别:
Evaluation of the AccuCirc for Early Infant Male Circumcision in Nyanza, Kenya
肯尼亚 Nyanza 的 AccuCirc 对早期婴儿男性包皮环切术的评估
- 批准号:
9198088 - 财政年份:2015
- 资助金额:
$ 18.4万 - 项目类别:
Integration of infant male circumcision with community health services in Kenya
肯尼亚将婴儿男性包皮环切术与社区卫生服务相结合
- 批准号:
8295437 - 财政年份:2012
- 资助金额:
$ 18.4万 - 项目类别:
Integration of infant male circumcision with community health services in Kenya
肯尼亚将婴儿男性包皮环切术与社区卫生服务相结合
- 批准号:
8884254 - 财政年份:2012
- 资助金额:
$ 18.4万 - 项目类别:
Integration of infant male circumcision with community health services in Kenya
肯尼亚将婴儿男性包皮环切术与社区卫生服务相结合
- 批准号:
8705384 - 财政年份:2012
- 资助金额:
$ 18.4万 - 项目类别:
Integration of infant male circumcision with community health services in Kenya
肯尼亚将婴儿男性包皮环切术与社区卫生服务相结合
- 批准号:
8487355 - 财政年份:2012
- 资助金额:
$ 18.4万 - 项目类别:
HIV/STI outcomes from male circumcision in men and female partners: Kisumu, Kenya
男性和女性伴侣男性包皮环切术的艾滋病毒/性传播感染结果:肯尼亚基苏木
- 批准号:
8136861 - 财政年份:2010
- 资助金额:
$ 18.4万 - 项目类别:
Trial of Male Circumcision to Reduce HIV Incidence
男性包皮环切术降低艾滋病毒发病率的试验
- 批准号:
7923519 - 财政年份:2009
- 资助金额:
$ 18.4万 - 项目类别:
Trial of Male Circumcision to Reduce HIV Incidence
男性包皮环切术降低艾滋病毒发病率的试验
- 批准号:
7163945 - 财政年份:2001
- 资助金额:
$ 18.4万 - 项目类别:
Trial of Male Circumcision to Reduce HIV Incidence
男性包皮环切术降低艾滋病毒发病率的试验
- 批准号:
7479621 - 财政年份:2001
- 资助金额:
$ 18.4万 - 项目类别:
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